Florian Georgescauld
Florian Georgescauld
Northeastern University, MA
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GroEL/ES chaperonin modulates the mechanism and accelerates the rate of TIM-barrel domain folding
F Georgescauld, K Popova, AJ Gupta, A Bracher, JR Engen, ...
Cell 157 (4), 922-934, 2014
Developments in hydrogen/deuterium exchange mass spectrometry
JR Engen, T Botzanowski, D Peterle, F Georgescauld, TE Wales
Analytical chemistry 93 (1), 567-582, 2020
Crystal structures of S120G mutant and wild type of human nucleoside diphosphate kinase A in complex with ADP
MF Giraud, F Georgescauld, I Lascu, A Dautant
Journal of bioenergetics and biomembranes 38, 261-264, 2006
The structure of the Escherichia coli nucleoside diphosphate kinase reveals a new quaternary architecture for this enzyme family
L Moynié, MF Giraud, F Georgescauld, I Lascu, A Dautant
PROTEINS: Structure, Function, and Bioinformatics 67 (3), 755-765, 2007
Deep structural analysis of RPAP3 and PIH1D1, two components of the HSP90 co-chaperone R2TP complex
J Henri, ME Chagot, M Bourguet, Y Abel, G Terral, C Maurizy, ...
Structure 26 (9), 1196-1209. e8, 2018
Structure, folding and stability of nucleoside diphosphate kinases
F Georgescauld, Y Song, A Dautant
International journal of molecular sciences 21 (18), 6779, 2020
Rescue of the neuroblastoma mutant of the human nucleoside diphosphate kinase A/nm23-H1 by the natural osmolyte trimethylamine-N-oxide
F Georgescauld, I Mocan, ML Lacombe, I Lascu
FEBS letters 583 (4), 820-824, 2009
Protein phosphorylation corrects the folding defect of the neuroblastoma (S120G) mutant of human nucleoside diphosphate kinase A/Nm23-H1
I Mocan, F Georgescauld, P Gonin, D Thoraval, L Cervoni, A Giartosio, ...
Biochemical Journal 403 (1), 149-156, 2007
Intersubunit ionic interactions stabilize the nucleoside diphosphate kinase of Mycobacterium tuberculosis
F Georgescauld, L Moynié, J Habersetzer, L Cervoni, I Mocan, T Borza, ...
PloS one 8 (3), e57867, 2013
An intersubunit disulfide bridge stabilizes the tetrameric nucleoside diphosphate kinase of Aquifex aeolicus
F Boissier, F Georgescauld, L Moynié, JW Dupuy, C Sarger, M Podar, ...
Proteins: Structure, Function, and Bioinformatics 80 (6), 1658-1668, 2012
Hydrogen/Deuterium Exchange Mass Spectrometry reveals mechanistic details of activation of nucleoside diphosphate kinases by oligomerization
A Dautant, P Meyer, F Georgescauld
Biochemistry 56 (23), 2886-2896, 2017
Aggregation of the neuroblastoma-associated mutant (S120G) of the human nucleoside diphosphate kinase-A/NM23-H1 into amyloid fibrils
F Georgescauld, R Sabaté, A Espargaró, S Ventura, S Chaignepain, ...
Naunyn-Schmiedeberg's archives of pharmacology 384, 373-381, 2011
A conservative point mutation in a dynamic antigen-binding loop of human immunoglobulin λ6 light chain promotes pathologic amyloid formation
D Peterle, ES Klimtchuk, TE Wales, F Georgescauld, LH Connors, ...
Journal of molecular biology 433 (24), 167310, 2021
Hydrogen deuterium exchange mass spectrometry applied to chaperones and chaperone-assisted protein folding
F Georgescauld, TE Wales, JR Engen
Expert Review of Proteomics 16 (7), 613-625, 2019
Structure of Mycobacterium tuberculosis nucleoside diphosphate kinase R80N mutant in complex with citrate
F Georgescauld, L Moynié, J Habersetzer, A Dautant
Acta Crystallographica Section F: Structural Biology Communications 70 (1 …, 2014
Role of molecular chaperones in protein folding
K Chakraborty, F Georgescauld, M Hayer-Hartl, FU Hartl
Protein misfolding and diseases: current and emerging principles and …, 2010
Remodeling of the binding site of nucleoside diphosphate kinase revealed by X-ray structure and H/D exchange
A Dautant, J Henri, TE Wales, P Meyer, JR Engen, F Georgescauld
Biochemistry 58 (10), 1440-1449, 2019
Native Capillary Electrophoresis–Mass Spectrometry of Near 1 MDa Non‐Covalent GroEL/GroES/Substrate Protein Complexes
AL Marie, F Georgescauld, KR Johnson, S Ray, JR Engen, AR Ivanov
Advanced Science, 2306824, 2024
Novel Structural Analysis of Pathogenic Tau Proteins in AD/ADRDs
F Georgescauld, BT Hyman, ST Brady, J Engen, Y Song
Alzheimer's Association International Conference, 2023
Protein Folding in Vivo
F Georgescauld, FU Hartl
eLS, 1-9, 2015
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