Megan O'Mara
Megan O'Mara
Professor, Australian Institute for Bioengineering and Nanotechnology, University of Queensland
Verified email at
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Mechanism of activation of protein kinase JAK2 by the growth hormone receptor
AJ Brooks, W Dai, ML O’Mara, D Abankwa, Y Chhabra, RA Pelekanos, ...
Science 344 (6185), 1249783, 2014
ABC transporters: a riddle wrapped in a mystery inside an enigma
PM Jones, ML O’Mara, AM George
Trends in biochemical sciences 34 (10), 520-531, 2009
ATP-binding cassette transporters in Escherichia coli
A Moussatova, C Kandt, ML O'Mara, DP Tieleman
Biochimica et Biophysica Acta (BBA)-Biomembranes 1778 (9), 1757-1771, 2008
The ryanodine receptor store-sensing gate controls Ca2+ waves and Ca2+-triggered arrhythmias
W Chen, R Wang, B Chen, X Zhong, H Kong, Y Bai, Q Zhou, C Xie, ...
Nature medicine 20 (2), 184-192, 2014
The mechanism of ABC transporters: general lessons from structural and functional studies of an antigenic peptide transporter
E Procko, ML O'Mara, WFD Bennett, DP Tieleman, R Gaudet
The FASEB Journal 23 (5), 1287-1302, 2009
Imperfect coordination chemistry facilitates metal ion release in the Psa permease
RM Couñago, MP Ween, SL Begg, M Bajaj, J Zuegg, ML O'mara, ...
Nature chemical biology 10 (1), 35-41, 2014
P-glycoprotein models of the apo and ATP-bound states based on homology with Sav1866 and MalK
ML O’Mara, DP Tieleman
FEBS letters 581 (22), 4217-4222, 2007
Structural arrangement of the transmission interface in the antigen ABC transport complex TAP
G Oancea, ML O'Mara, WFD Bennett, DP Tieleman, R Abele, R Tampé
Proceedings of the National Academy of Sciences 106 (14), 5551-5556, 2009
Structure of a lipid A phosphoethanolamine transferase suggests how conformational changes govern substrate binding
A Anandan, GL Evans, K Condic-Jurkic, ML O’Mara, CM John, NJ Phillips, ...
Proceedings of the National Academy of Sciences 114 (9), 2218-2223, 2017
Dysregulation of transition metal ion homeostasis is the molecular basis for cadmium toxicity in Streptococcus pneumoniae
SL Begg, BA Eijkelkamp, Z Luo, RM Couñago, JR Morey, MJ Maher, ...
Nature communications 6 (1), 1-11, 2015
Synthetically controlling dendrimer flexibility improves delivery of large plasmid DNA
JA Kretzmann, D Ho, CW Evans, JHC Plani-Lam, B Garcia-Bloj, ...
Chemical science 8 (4), 2923-2930, 2017
AdcA and AdcAII employ distinct zinc acquisition mechanisms and contribute additively to zinc homeostasis in Streptococcus pneumoniae
CD Plumptre, BA Eijkelkamp, JR Morey, F Behr, RM Couñago, ...
Molecular microbiology 91 (4), 834-851, 2014
Conduction mechanisms of chloride ions in ClC-type channels
B Corry, M O’Mara, SH Chung
Biophysical journal 86 (2), 846-860, 2004
Homology model of the GABAA receptor examined using Brownian dynamics
M O’Mara, B Cromer, M Parker, SH Chung
Biophysical journal 88 (5), 3286-3299, 2005
Intestinal peptidases form functional complexes with the neutral amino acid transporter B0AT1
SJ Fairweather, A Bröer, ML O'Mara, S Bröer
Biochemical Journal 446 (1), 135-148, 2012
The effect of environment on the structure of a membrane protein: P-glycoprotein under physiological conditions
ML O’Mara, AE Mark
Journal of Chemical Theory and Computation 8 (10), 3964-3976, 2012
Residue G346 in transmembrane segment six is involved in inter-domain communication in P-glycoprotein
J Storm, ML O'Mara, EH Crowley, J Peall, DP Tieleman, ID Kerr, ...
Biochemistry 46 (35), 9899-9910, 2007
Structure-based interpretation of the mutagenesis database for the nucleotide binding domains of P-glycoprotein
J Lawson, ML O'Mara, ID Kerr
Biochimica et Biophysica Acta (BBA)-Biomembranes 1778 (2), 376-391, 2008
Vancomycin: ligand recognition, dimerization and super‐complex formation
ZG Jia, ML O'Mara, J Zuegg, MA Cooper, AE Mark
The FEBS journal 280 (5), 1294-1307, 2013
Molecular basis for the interaction of the mammalian amino acid transporters B0AT1 and B0AT3 with their ancillary protein collectrin
SJ Fairweather, A Bröer, N Subramanian, E Tumer, Q Cheng, D Schmoll, ...
Journal of Biological Chemistry 290 (40), 24308-24325, 2015
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