Mechanism of early dissemination and metastasis in Her2+ mammary cancer KL Harper, MS Sosa, D Entenberg, H Hosseini, JF Cheung, R Nobre, ... Nature 540 (7634), 588-592, 2016 | 517 | 2016 |
Phenotypic heterogeneity of disseminated tumour cells is preset by primary tumour hypoxic microenvironments G Fluegen, A Avivar-Valderas, Y Wang, MR Padgen, JK Williams, ... Nature cell biology 19 (2), 120-132, 2017 | 299 | 2017 |
P-cadherin role in normal breast development and cancer A Albergaria, AS Ribeiro, AF Vieira, B Sousa, AR Nobre, R Seruca, ... International Journal of Developmental Biology 55 (7-8-9), 811-822, 2011 | 157 | 2011 |
Axl is required for TGF-β2-induced dormancy of prostate cancer cells in the bone marrow K Yumoto, MR Eber, J Wang, FC Cackowski, AM Decker, E Lee, ... Scientific reports 6 (1), 36520, 2016 | 154 | 2016 |
The current paradigm and challenges ahead for the dormancy of disseminated tumor cells E Risson, AR Nobre, V Maguer-Satta, JA Aguirre-Ghiso Nature Cancer 1 (7), 672-680, 2020 | 149 | 2020 |
A tumor-derived type III collagen-rich ECM niche regulates tumor cell dormancy JS Di Martino, AR Nobre, C Mondal, I Taha, EF Farias, EJ Fertig, A Naba, ... Nature cancer 3 (1), 90-107, 2022 | 143 | 2022 |
The different routes to metastasis via hypoxia-regulated programs AR Nobre, D Entenberg, Y Wang, J Condeelis, JA Aguirre-Ghiso Trends in cell biology 28 (11), 941-956, 2018 | 97 | 2018 |
P‐cadherin functional role is dependent on E‐cadherin cellular context: a proof of concept using the breast cancer model AS Ribeiro, B Sousa, L Carreto, N Mendes, AR Nobre, S Ricardo, ... The Journal of pathology 229 (5), 705-718, 2013 | 96 | 2013 |
p40: a p63 isoform useful for lung cancer diagnosis–a review of the physiological and pathological role of p63 AR Nobre, A Albergaria, F Schmitt Acta Cytologica 57 (1), 1-8, 2013 | 89 | 2013 |
Bone marrow NG2+/Nestin+ mesenchymal stem cells drive DTC dormancy via TGF-β2 AR Nobre, E Risson, DK Singh, JS Di Martino, JF Cheung, J Wang, ... Nature Cancer 2 (3), 327-339, 2021 | 83 | 2021 |
P-cadherin signals through the laminin receptor α6β4 integrin to induce stem cell and invasive properties in basal-like breast cancer cells AF Vieira, AS Ribeiro, MR Dionísio, B Sousa, AR Nobre, A Albergaria, ... Oncotarget 5 (3), 679, 2014 | 69 | 2014 |
An NR2F1-specific agonist suppresses metastasis by inducing cancer cell dormancy BD Khalil, R Sanchez, T Rahman, C Rodriguez-Tirado, S Moritsch, ... Journal of Experimental Medicine 219 (1), e20210836, 2021 | 49 | 2021 |
ZFP281 drives a mesenchymal-like dormancy program in early disseminated breast cancer cells that prevents metastatic outgrowth in the lung AR Nobre, E Dalla, J Yang, X Huang, L Wullkopf, E Risson, P Razghandi, ... Nature Cancer 3 (10), 1165-1180, 2022 | 38 | 2022 |
The basal epithelial marker P-cadherin associates with breast cancer cell populations harboring a glycolytic and acid-resistant phenotype B Sousa, AS Ribeiro, AR Nobre, N Lopes, D Martins, C Pinheiro, ... BMC cancer 14, 1-13, 2014 | 36 | 2014 |
CCAAT/Enhancer Binding Protein β (C/EBPβ) Isoforms as Transcriptional Regulators of the Pro-Invasive CDH3/P-Cadherin Gene in Human Breast Cancer Cells A Albergaria, C Resende, AR Nobre, AS Ribeiro, B Sousa, JC Machado, ... PloS one 8 (2), e55749, 2013 | 24 | 2013 |
SRC inhibition prevents P-cadherin mediated signaling and function in basal-like breast cancer cells AS Ribeiro, AR Nobre, N Mendes, J Almeida, AF Vieira, B Sousa, ... Cell Communication and Signaling 16, 1-16, 2018 | 19 | 2018 |
Correction: Corrigendum: Mechanism of early dissemination and metastasis in Her2+ mammary cancer KL Harper, MS Sosa, D Entenberg, H Hosseini, JF Cheung, R Nobre, ... Nature 553 (7688), 366-366, 2018 | 9 | 2018 |
A mesenchymal-like program of dormancy controlled by ZFP281 serves as a barrier to metastatic progression of early disseminated cancer cells J Aguirre-Ghiso, AR Nobre, E Dalla, J Yang, X Huang, E Kenigsberg, ... | 7 | 2021 |
5-Azacytidine-and retinoic-acid-induced reprogramming of DCCs into dormancy suppresses metastasis via restored TGF-β-SMAD4 signaling DK Singh, S Carcamo, EF Farias, D Hasson, W Zheng, D Sun, X Huang, ... Cell reports 42 (6), 2023 | 5 | 2023 |
A specific agonist of the orphan nuclear receptor NR2F1 suppresses metastasis through the induction of cancer cell dormancy BD Khalil, R Sanchez, T Rahman, C Rodriguez-Tirado, S Moritsch, ... bioRxiv, 2021.01. 30.428967, 2021 | 5 | 2021 |