Comprehensive metabolic profiling and phenotyping of interspecific introgression lines for tomato improvement N Schauer, Y Semel, U Roessner, A Gur, I Balbo, F Carrari, T Pleban, ... Nature biotechnology 24 (4), 447-454, 2006 | 794 | 2006 |
Metabolic profiling of transgenic tomato plants overexpressing hexokinase reveals that the influence of hexose phosphorylation diminishes during fruit development U Roessner-Tunali, B Hegemann, A Lytovchenko, F Carrari, C Bruedigam, ... Plant Physiology 133 (1), 84-99, 2003 | 368 | 2003 |
Depletion of Jak2V617F myeloproliferative neoplasm-propagating stem cells by interferon-α in a murine model of polycythemia vera A Mullally, C Bruedigam, L Poveromo, FH Heidel, A Purdon, T Vu, ... Blood, The Journal of the American Society of Hematology 121 (18), 3692-3702, 2013 | 159 | 2013 |
A new concept underlying stem cell lineage skewing that explains the detrimental effects of thiazolidinediones on bone C Bruedigam, M Eijken, M Koedam, J van de Peppel, K Drabek, H Chiba, ... Stem cells 28 (5), 916-927, 2010 | 92 | 2010 |
NK cells require IL-28R for optimal in vivo activity F Souza-Fonseca-Guimaraes, A Young, D Mittal, L Martinet, C Bruedigam, ... Proceedings of the National Academy of Sciences 112 (18), E2376-E2384, 2015 | 85 | 2015 |
Telomerase inhibition effectively targets mouse and human AML stem cells and delays relapse following chemotherapy C Bruedigam, FO Bagger, FH Heidel, CP Kuhn, S Guignes, A Song, ... Cell stem cell 15 (6), 775-790, 2014 | 80 | 2014 |
Basic techniques in human mesenchymal stem cell cultures: differentiation into osteogenic and adipogenic lineages, genetic perturbations, and phenotypic analyses C Bruedigam, M Driel, M Koedam, J Peppel, BCJ van der Eerden, ... Current protocols in stem cell biology 17 (1), 1H. 3.1-1H. 3.20, 2011 | 58 | 2011 |
Intact TP-53 function is essential for sustaining durable responses to BH3-mimetic drugs in leukemias R Thijssen, ST Diepstraten, D Moujalled, E Chew, C Flensburg, MX Shi, ... Blood, The Journal of the American Society of Hematology 137 (20), 2721-2735, 2021 | 50 | 2021 |
Autophagy is required for stem cell mobilization by G-CSF L Leveque-El Mouttie, T Vu, KE Lineburg, RD Kuns, FO Bagger, BE Teal, ... Blood, The Journal of the American Society of Hematology 125 (19), 2933-2936, 2015 | 40 | 2015 |
Evidence for multiple peroxisome proliferator-activated receptor γ transcripts in bone: Fine-tuning by hormonal regulation and mRNA stability C Bruedigam, M Koedam, H Chiba, M Eijken, JPTM van Leeuwen FEBS letters 582 (11), 1618-1624, 2008 | 33 | 2008 |
Distinct effects of ruxolitinib and interferon-alpha on murine JAK2V617F myeloproliferative neoplasm hematopoietic stem cell populations RJ Austin, J Straube, C Bruedigam, G Pali, S Jacquelin, T Vu, J Green, ... Leukemia 34 (4), 1075-1089, 2020 | 29 | 2020 |
EphA2 is a therapy target in EphA2-positive leukemias but is not essential for normal hematopoiesis or leukemia S Charmsaz, K Beckett, FM Smith, C Bruedigam, AS Moore, F Al-Ejeh, ... PloS one 10 (6), e0130692, 2015 | 23 | 2015 |
1α, 25-dihydroxyvitamin D3 and rosiglitazone synergistically enhance osteoblast-mediated mineralization VJ Woeckel, C Bruedigam, M Koedam, H Chiba, BCJ van der Eerden, ... Gene 512 (2), 438-443, 2013 | 21 | 2013 |
Hematopoietic stem and progenitor cell-restricted Cdx2 expression induces transformation to myelodysplasia and acute leukemia T Vu, J Straube, AH Porter, M Bywater, A Song, V Ling, L Cooper, G Pali, ... Nature Communications 11 (1), 3021, 2020 | 15 | 2020 |
Telomerase in hematologic malignancies C Bruedigam, SW Lane Current Opinion in Hematology 23 (4), 346-353, 2016 | 15 | 2016 |
Acute myeloid leukemia stem cell function is preserved in the absence of autophagy AH Porter, L Leveque-El Mouttie, T Vu, C Bruedigam, J Sutton, ... Haematologica 102 (9), e344, 2017 | 12 | 2017 |
Opposing actions of rosiglitazone and resveratrol on mineralization in human vascular smooth muscle cells C Bruedigam, M Eijken, M Koedam, H Chiba, JPTM van Leeuwen Journal of Molecular and Cellular Cardiology 51 (5), 862-871, 2011 | 11 | 2011 |
Jak2V617F driven myeloproliferative neoplasm occurs independently of interleukin-3 receptor beta common signaling T Vu, R Austin, CP Kuhn, C Bruedigam, A Song, S Guignes, S Jacquelin, ... Haematologica 101 (3), e77, 2016 | 8 | 2016 |
Autophagy is required for long-term hematopoietic stem cell (HSC) function and G-CSF-induced HSC mobilization L Leveque, T Vu, RD Kuns, BE Teal, M Lor, KE Lineburg, C Bruedigam, ... Blood 122 (21), 892, 2013 | 5 | 2013 |
Epigenetic activation of plasmacytoid DCs drives IFNAR-dependent therapeutic differentiation of AML JM Salmon, I Todorovski, KL Stanley, C Bruedigam, CJ Kearney, ... Cancer Discovery 12 (6), 1560-1579, 2022 | 4 | 2022 |