Selective targeting of engineered T cells using orthogonal IL-2 cytokine-receptor complexes JT Sockolosky, E Trotta, G Parisi, L Picton, LL Su, AC Le, A Chhabra, ... Science 359 (6379), 1037-1042, 2018 | 316 | 2018 |
Antigen identification for orphan T cell receptors expressed on tumor-infiltrating lymphocytes MH Gee, A Han, SM Lofgren, JF Beausang, JL Mendoza, ME Birnbaum, ... Cell 172 (3), 549-563. e16, 2018 | 287 | 2018 |
Isolation of a structural mechanism for uncoupling T cell receptor signaling from peptide-MHC binding LV Sibener, RA Fernandes, EM Kolawole, CB Carbone, F Liu, D McAffee, ... Cell 174 (3), 672-687. e27, 2018 | 275 | 2018 |
Crystal structure of Vδ1 T cell receptor in complex with CD1d-sulfatide shows MHC-like recognition of a self-lipid by human γδ T cells AM Luoma, CD Castro, T Mayassi, LA Bembinster, L Bai, D Picard, ... Immunity 39 (6), 1032-1042, 2013 | 258 | 2013 |
Nanoscale artificial antigen presenting cells for T cell immunotherapy K Perica, ADL Medero, M Durai, YL Chiu, JG Bieler, L Sibener, ... Nanomedicine: Nanotechnology, Biology and Medicine 10 (1), 119-129, 2014 | 162 | 2014 |
Genetic variation in MHC proteins is associated with T cell receptor expression biases E Sharon, LV Sibener, A Battle, HB Fraser, KC Garcia, JK Pritchard Nature genetics 48 (9), 995-1002, 2016 | 159 | 2016 |
Structural interplay between germline interactions and adaptive recognition determines the bandwidth of TCR-peptide-MHC cross-reactivity JJ Adams, S Narayanan, ME Birnbaum, SS Sidhu, SJ Blevins, MH Gee, ... Nature immunology 17 (1), 87-94, 2016 | 134 | 2016 |
Lysophospholipid presentation by CD1d and recognition by a human Natural Killer T‐cell receptor J López‐Sagaseta, LV Sibener, JE Kung, J Gumperz, EJ Adams The EMBO journal 31 (8), 2047-2059, 2012 | 75 | 2012 |
Tuning T cell receptor sensitivity through catch bond engineering X Zhao, EM Kolawole, W Chan, Y Feng, X Yang, MH Gee, KM Jude, ... Science 376 (6589), eabl5282, 2022 | 74 | 2022 |
Discovery of surrogate agonists for visceral fat Treg cells that modulate metabolic indices in vivo RA Fernandes, C Li, G Wang, X Yang, CS Savvides, CR Glassman, ... Elife 9, e58463, 2020 | 32 | 2020 |
Stress-testing the relationship between T cell receptor/peptide-MHC affinity and cross-reactivity using peptide velcro MH Gee, LV Sibener, ME Birnbaum, KM Jude, X Yang, RA Fernandes, ... Proceedings of the National Academy of Sciences 115 (31), E7369-E7378, 2018 | 27 | 2018 |
Identification of antigenic targets HP Gerber, LV Sibener, LJ Lee, MH Gee Trends in Cancer 6 (4), 299-318, 2020 | 10 | 2020 |
Intracellular targets as source for cleaner targets for the treatment of solid tumors HP Gerber, LV Sibener, LJ Lee, M Gee Biochemical Pharmacology 168, 275-284, 2019 | 10 | 2019 |
TCR ligand potency differentially impacts PD-1 inhibitory effects on diverse signaling pathways W Chan, YM Cao, X Zhao, EC Schrom, D Jia, J Song, LV Sibener, S Dong, ... Journal of Experimental Medicine 220 (12), e20231242, 2023 | 6 | 2023 |
Voices of biotech leaders AE Abong, K Bosley, C Casebourn, P Chan, J Chen, M Chen, G Church, ... Nature Biotechnology 39 (6), 654-660, 2021 | 5 | 2021 |
Isolation and visualization of a structural trigger that uncouples TCR signaling from pMHC binding LV Sibener, RA Fernandes, EM Kolawole, CB Carbone, F Liu, D McAffee, ... Cell 174 (3), 672, 2018 | 4 | 2018 |
Antigen-specificity of clonally-enriched CD8+ T cells in multiple sclerosis K Mittl, F Hayashi, R Dandekar, RD Schubert, J Gerdts, L Oshiro, ... bioRxiv, 2024.09. 07.611010, 2024 | | 2024 |
T cell receptor (tcr) compositions and methods for optimizing antigen reactive t-cells L Sibener, J Leonard, M Gee, J Byers US Patent App. 18/157,605, 2023 | | 2023 |
T cell receptor (tcr) compositions and methods for optimizing antigen reactive t-cells L Sibener, J Leonard, A Ramirez, M Gee US Patent App. 18/157,598, 2023 | | 2023 |
T cell receptor (tcr) compositions and methods for optimizing antigen reactive t-cells L Sibener, J Leonard, M Gee US Patent App. 18/157,623, 2023 | | 2023 |