Tetrazine ligation: fast bioconjugation based on inverse-electron-demand Diels− Alder reactivity ML Blackman, M Royzen, JM Fox Journal of the American Chemical Society 130 (41), 13518-13519, 2008 | 1745 | 2008 |
Highly active and selective catalysts for the formation of α-aryl ketones JM Fox, X Huang, A Chieffi, SL Buchwald Journal of the American Chemical Society 122 (7), 1360-1370, 2000 | 662 | 2000 |
Genetic Encoding of Bicyclononynes and trans-Cyclooctenes for Site-Specific Protein Labeling in Vitro and in Live Mammalian Cells via Rapid Fluorogenic Diels … K Lang, L Davis, S Wallace, M Mahesh, DJ Cox, ML Blackman, JM Fox, ... Journal of the American Chemical Society 134 (25), 10317-10320, 2012 | 586 | 2012 |
Design and Synthesis of Highly Reactive Dienophiles for the Tetrazine–trans-Cyclooctene Ligation MT Taylor, ML Blackman, O Dmitrenko, JM Fox Journal of the American Chemical Society 133 (25), 9646-9649, 2011 | 383 | 2011 |
An improved synthesis of functionalized biphenyl-based phosphine ligands H Tomori, JM Fox, SL Buchwald The Journal of Organic Chemistry 65 (17), 5334-5341, 2000 | 309 | 2000 |
Genetically Encoded Tetrazine Amino Acid Directs Rapid Site-Specific in Vivo Bioorthogonal Ligation with trans-Cyclooctenes JL Seitchik, JC Peeler, MT Taylor, ML Blackman, TW Rhoads, RB Cooley, ... Journal of the American Chemical Society 134 (6), 2898-2901, 2012 | 295 | 2012 |
Diels–Alder cycloaddition for fluorophore targeting to specific proteins inside living cells DS Liu, A Tangpeerachaikul, R Selvaraj, MT Taylor, JM Fox, AY Ting Journal of the American Chemical Society 134 (2), 792-795, 2012 | 282 | 2012 |
Conformationally strained trans-cyclooctene with improved stability and excellent reactivity in tetrazine ligation A Darko, S Wallace, O Dmitrenko, MM Machovina, RA Mehl, JW Chin, ... Chemical science 5 (10), 3770-3776, 2014 | 256 | 2014 |
trans-Cyclooctene—a stable, voracious dienophile for bioorthogonal labeling R Selvaraj, JM Fox Current opinion in chemical biology 17 (5), 753-760, 2013 | 248 | 2013 |
Synthesis, self-assembly, and nonlinear optical properties of conjugated helical metal phthalocyanine derivatives JM Fox, TJ Katz, S Van Elshocht, T Verbiest, M Kauranen, A Persoons, ... Journal of the American Chemical Society 121 (14), 3453-3459, 1999 | 235 | 1999 |
Bioorthogonal chemistry SL Scinto, DA Bilodeau, R Hincapie, W Lee, SS Nguyen, M Xu, ... Nature Reviews Methods Primers 1 (1), 30, 2021 | 219 | 2021 |
A Photochemical Synthesis of Functionalized trans-Cyclooctenes Driven by Metal Complexation M Royzen, GPA Yap, JM Fox Journal of the American Chemical Society 130 (12), 3760-3761, 2008 | 218 | 2008 |
Catalytic asymmetric vinylation of ketone enolates A Chieffi, K Kamikawa, J Åhman, JM Fox, SL Buchwald Organic Letters 3 (12), 1897-1900, 2001 | 209 | 2001 |
Tetrazine–trans-cyclooctene ligation for the rapid construction of 18F labeled probes Z Li, H Cai, M Hassink, ML Blackman, RCD Brown, PS Conti, JM Fox Chemical Communications 46 (42), 8043-8045, 2010 | 201 | 2010 |
Chiral Crown Conformation of Rh2(S-PTTL)4: Enantioselective Cyclopropanation with α-Alkyl-α-diazoesters A DeAngelis, O Dmitrenko, GPA Yap, JM Fox Journal of the American Chemical Society 131 (21), 7230-7231, 2009 | 191 | 2009 |
Rh-catalyzed intermolecular reactions of alkynes with α-diazoesters that possess β-hydrogens: ligand-based control over divergent pathways P Panne, JM Fox Journal of the American Chemical Society 129 (1), 22-23, 2007 | 187 | 2007 |
Rhodium (II)-catalyzed enantioselective C− H functionalization of indoles A DeAngelis, VW Shurtleff, O Dmitrenko, JM Fox Journal of the American Chemical Society 133 (6), 1650-1653, 2011 | 177 | 2011 |
Metal mediated and catalyzed nucleophilic additions to cyclopropenes JM Fox, N Yan Current organic chemistry 9 (7), 719-732, 2005 | 171 | 2005 |
Systematic evaluation of bioorthogonal reactions in live cells with clickable HaloTag ligands: implications for intracellular imaging HE Murrey, JC Judkins, CW Am Ende, TE Ballard, Y Fang, K Riccardi, ... Journal of the American Chemical Society 137 (35), 11461-11475, 2015 | 160 | 2015 |
Rh-catalyzed intermolecular reactions of α-alkyl-α-diazo carbonyl compounds with selectivity over β-hydride migration A DeAngelis, R Panish, JM Fox Accounts of chemical research 49 (1), 115-127, 2016 | 159 | 2016 |