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Nicolas Stransky
Nicolas Stransky
Celsius Therapeutics
Adresse e-mail validée de celsiustx.com
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The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity
J Barretina, G Caponigro, N Stransky, K Venkatesan, AA Margolin, S Kim, ...
Nature 483 (7391), 603-607, 2012
67822012
Mutational heterogeneity in cancer and the search for new cancer-associated genes
MS Lawrence, P Stojanov, P Polak, GV Kryukov, K Cibulskis, ...
Nature 499 (7457), 214-218, 2013
51882013
A landscape of driver mutations in melanoma
E Hodis, IR Watson, GV Kryukov, ST Arold, M Imielinski, JP Theurillat, ...
Cell 150 (2), 251-263, 2012
26682012
The mutational landscape of head and neck squamous cell carcinoma
N Stransky, AM Egloff, AD Tward, AD Kostic, K Cibulskis, A Sivachenko, ...
Science 333 (6046), 1157-1160, 2011
25662011
Comprehensive genomic characterization defines human glioblastoma genes and core pathways
Cancer Genome Atlas Research Network Tissue source sites: Duke University ...
Nature 455 (7216), 1061-1068, 2008
19122008
Next-generation characterization of the cancer cell line encyclopedia
M Ghandi, FW Huang, J Jané-Valbuena, GV Kryukov, CC Lo, ...
Nature 569 (7757), 503-508, 2019
16412019
COT drives resistance to RAF inhibition through MAP kinase pathway reactivation
CM Johannessen, JS Boehm, SY Kim, SR Thomas, L Wardwell, ...
Nature 468 (7326), 968-972, 2010
16392010
Exome sequencing identifies recurrent SPOP, FOXA1 and MED12 mutations in prostate cancer
CE Barbieri, SC Baca, MS Lawrence, F Demichelis, M Blattner, ...
Nature genetics 44 (6), 685-689, 2012
15882012
Comprehensive and integrative genomic characterization of hepatocellular carcinoma
A Ally, M Balasundaram, R Carlsen, E Chuah, A Clarke, N Dhalla, RA Holt, ...
Cell 169 (7), 1327-1341. e23, 2017
14832017
Functional genomics reveal that the serine synthesis pathway is essential in breast cancer
R Possemato, KM Marks, YD Shaul, ME Pacold, D Kim, K Birsoy, ...
Nature 476 (7360), 346-350, 2011
14742011
Sequence analysis of mutations and translocations across breast cancer subtypes
S Banerji, K Cibulskis, C Rangel-Escareno, KK Brown, SL Carter, ...
Nature 486 (7403), 405-409, 2012
13092012
Discovery and prioritization of somatic mutations in diffuse large B-cell lymphoma (DLBCL) by whole-exome sequencing
JG Lohr, P Stojanov, MS Lawrence, D Auclair, B Chapuy, C Sougnez, ...
Proceedings of the National Academy of Sciences 109 (10), 3879-3884, 2012
10362012
The landscape of kinase fusions in cancer
N Stransky, E Cerami, S Schalm, JL Kim, C Lengauer
Nature communications 5 (1), 4846, 2014
8472014
Melanoma genome sequencing reveals frequent PREX2 mutations
MF Berger, E Hodis, TP Heffernan, YL Deribe, MS Lawrence, ...
Nature 485 (7399), 502-506, 2012
8312012
Analysis of array CGH data: from signal ratio to gain and loss of DNA regions
P Hupe, N Stransky, JP Thiery, F Radvanyi, E Barillot
Bioinformatics 20 (18), 3413-3422, 2004
6732004
An interactive resource to identify cancer genetic and lineage dependencies targeted by small molecules
A Basu, NE Bodycombe, JH Cheah, EV Price, K Liu, GI Schaefer, ...
Cell 154 (5), 1151-1161, 2013
5942013
Integrative genomic analysis of cholangiocarcinoma identifies distinct IDH-mutant molecular profiles
F Farshidfar, S Zheng, MC Gingras, Y Newton, J Shih, AG Robertson, ...
Cell reports 18 (11), 2780-2794, 2017
5192017
Systematic investigation of genetic vulnerabilities across cancer cell lines reveals lineage-specific dependencies in ovarian cancer
HW Cheung, GS Cowley, BA Weir, JS Boehm, S Rusin, JA Scott, A East, ...
Proceedings of the National Academy of Sciences 108 (30), 12372-12377, 2011
4702011
Targeting cancer with kinase inhibitors
S Gross, R Rahal, N Stransky, C Lengauer, KP Hoeflich
The Journal of clinical investigation 125 (5), 1780-1789, 2015
4692015
Inhibitor-sensitive FGFR1 amplification in human non-small cell lung cancer
A Dutt, AH Ramos, PS Hammerman, C Mermel, J Cho, T Sharifnia, ...
PloS one 6 (6), e20351, 2011
4382011
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