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Thomas Roberts
Thomas Roberts
Professor, Harvard Medical School
Verified email at dfci.harvard.edu
Title
Cited by
Cited by
Year
SH2 domains recognize specific phosphopeptide sequences
S Zhou, SE Shoelson, M Chaudhuri, G Gish, T Pawson, WG Haser, F King, ...
Cell 72 (5), 767-778, 1993
35651993
Targeting the phosphoinositide 3-kinase pathway in cancer
P Liu, H Cheng, TM Roberts, JJ Zhao
Nature reviews Drug discovery 8 (8), 627-644, 2009
31202009
COT drives resistance to RAF inhibition through MAP kinase pathway reactivation
CM Johannessen, JS Boehm, SY Kim, SR Thomas, L Wardwell, ...
Nature 468 (7326), 968-972, 2010
17162010
CDK4/6 inhibition triggers anti-tumour immunity
S Goel, MJ DeCristo, AC Watt, H BrinJones, J Sceneay, BB Li, N Khan, ...
Nature 548 (7668), 471-475, 2017
11752017
ras mediates nerve growth factor receptor modulation of three signal-transducing protein kinases: MAP kinase, Raf-1, and RSK
KW Wood, C Sarnecki, TM Roberts, J Blenis
Cell 68 (6), 1041-1050, 1992
11281992
Association of phosphatidylinositol kinase activity with polyoma middle-T competent for transformation
M Whitman, DR Kaplan, B Schaffhausen, L Cantley, TM Roberts
Nature 315 (6016), 239-242, 1985
9731985
A histone H3 lysine 27 demethylase regulates animal posterior development
F Lan, PE Bayliss, JL Rinn, JR Whetstine, JK Wang, S Chen, S Iwase, ...
Nature 449 (7163), 689-694, 2007
9042007
Activation of mitogen-activated protein kinase kinase by v-Raf in NIH 3T3 cells and in vitro
P Dent, W Haser, TAJ Haystead, LA Vincent, TM Roberts, TW Sturgill
Science 257 (5075), 1404-1407, 1992
8811992
Essential roles of PI (3) K–p110β in cell growth, metabolism and tumorigenesis
S Jia, Z Liu, S Zhang, P Liu, L Zhang, SH Lee, J Zhang, S Signoretti, ...
Nature 454 (7205), 776-779, 2008
8482008
Medulloblastoma exome sequencing uncovers subtype-specific somatic mutations
TJ Pugh, SD Weeraratne, TC Archer, DA Pomeranz Krummel, D Auclair, ...
Nature 488 (7409), 106-110, 2012
8282012
Common elements in growth factor stimulation and oncogenic transformation: 85 kd phosphoprotein and phosphatidylinositol kinase activity
DR Kaplan, M Whitman, B Schaffhausen, DC Pallas, M White, L Cantley, ...
Cell 50 (7), 1021-1029, 1987
7801987
The X-linked mental retardation gene SMCX/JARID1C defines a family of histone H3 lysine 4 demethylases
S Iwase, F Lan, P Bayliss, L de la Torre-Ubieta, M Huarte, HH Qi, ...
Cell 128 (6), 1077-1088, 2007
7622007
Regulation of G1 progression by the PTEN tumor suppressor protein is linked to inhibition of the phosphatidylinositol 3-kinase/Akt pathway
S Ramaswamy, N Nakamura, F Vazquez, DB Batt, S Perera, TM Roberts, ...
Proceedings of the National Academy of Sciences 96 (5), 2110-2115, 1999
7571999
Polyoma small and middle T antigens and SV40 small t antigen form stable complexes with protein phosphatase 2A
DC Pallas, LK Shahrik, BL Martin, S Jaspers, TB Miller, DL Brautigan, ...
Cell 60 (1), 167-176, 1990
7551990
KRAS and YAP1 converge to regulate EMT and tumor survival
DD Shao, W Xue, EB Krall, A Bhutkar, F Piccioni, X Wang, AC Schinzel, ...
Cell 158 (1), 171-184, 2014
7362014
Integrative genomic approaches identify IKBKE as a breast cancer oncogene
JS Boehm, JJ Zhao, J Yao, SY Kim, R Firestein, IF Dunn, SK Sjostrom, ...
Cell 129 (6), 1065-1079, 2007
7092007
Cloning of the β subunit of the leukocyte adhesion proteins: homology to an extracellular matrix receptor defines a novel supergene family
TK Kishimoto, K O'Connor, A Lee, TM Roberts, TA Springer
Cell 48 (4), 681-690, 1987
6361987
Tyrosine phosphorylation regulates the biochemical and biological properties of pp60c-src
H Piwnica-Worms, KB Saunders, TM Roberts, AE Smith, SH Cheng
Cell 49 (1), 75-82, 1987
6131987
An F876L mutation in androgen receptor confers genetic and phenotypic resistance to MDV3100 (enzalutamide)
M Korpal, JM Korn, X Gao, DP Rakiec, DA Ruddy, S Doshi, J Yuan, ...
Cancer discovery 3 (9), 1030-1043, 2013
6002013
Direct activation of the serine/threonine kinase activity of Raf-1 through tyrosine phosphorylation by the PDGF β-receptor
DK Morrison, DR Kaplan, JA Escobedo, UR Rapp, TM Roberts, ...
Cell 58 (4), 649-657, 1989
5961989
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