| GOT1 inhibition promotes pancreatic cancer cell death by ferroptosis DM Kremer, BS Nelson, L Lin, EL Yarosz, CJ Halbrook, SA Kerk, ... Nature communications 12 (1), 4860, 2021 | 142 | 2021 |
| HIF-2α activation potentiates oxidative cell death in colorectal cancers by increasing cellular iron R Singhal, SR Mitta, NK Das, SA Kerk, P Sajjakulnukit, S Solanki, ... The Journal of clinical investigation 131 (12), 2021 | 126 | 2021 |
| Metabolic networks in mutant KRAS-driven tumours: tissue specificities and the microenvironment SA Kerk, T Papagiannakopoulos, YM Shah, CA Lyssiotis Nature reviews Cancer 21 (8), 510-525, 2021 | 122 | 2021 |
| Reuterin in the healthy gut microbiome suppresses colorectal cancer growth through altering redox balance HN Bell, RJ Rebernick, J Goyert, R Singhal, M Kuljanin, SA Kerk, ... Cancer cell 40 (2), 185-200. e6, 2022 | 110 | 2022 |
| Hyaluronic acid fuels pancreatic cancer cell growth PK Kim, CJ Halbrook, SA Kerk, M Radyk, S Wisner, DM Kremer, ... Elife 10, e62645, 2021 | 61 | 2021 |
| Hepcidin sequesters iron to sustain nucleotide metabolism and mitochondrial function in colorectal cancer epithelial cells AJ Schwartz, JW Goyert, S Solanki, SA Kerk, B Chen, C Castillo, PP Hsu, ... Nature metabolism 3 (7), 969-982, 2021 | 61 | 2021 |
| High-content fluorescence imaging with the metabolic flux assay reveals insights into mitochondrial properties and functions AC Little, I Kovalenko, LE Goo, HS Hong, SA Kerk, JA Yates, V Purohit, ... Communications biology 3 (1), 271, 2020 | 56 | 2020 |
| 5T4-targeted therapy ablates cancer stem cells and prevents recurrence of head and neck squamous cell carcinoma SA Kerk, KA Finkel, AT Pearson, KA Warner, Z Zhang, F Nör, VP Wagner, ... Clinical Cancer Research 23 (10), 2516-2527, 2017 | 50 | 2017 |
| Menin regulates the serine biosynthetic pathway in Ewing sarcoma LK Svoboda, SSK Teh, S Sud, S Kerk, A Zebolsky, S Treichel, D Thomas, ... The Journal of pathology 245 (3), 324-336, 2018 | 44 | 2018 |
| Expansion of cat-ELCCA for the discovery of small molecule inhibitors of the pre-let-7–Lin28 RNA–protein interaction DA Lorenz, T Kaur, SA Kerk, EE Gallagher, J Sandoval, AL Garner ACS Medicinal Chemistry Letters 9 (6), 517-521, 2018 | 41 | 2018 |
| Extrinsic KRAS signaling shapes the pancreatic microenvironment through fibroblast reprogramming A Velez-Delgado, KL Donahue, KL Brown, W Du, V Irizarry-Negron, ... Cellular and Molecular Gastroenterology and Hepatology 13 (6), 1673-1699, 2022 | 39 | 2022 |
| Metabolic requirement for GOT2 in pancreatic cancer depends on environmental context SA Kerk, L Lin, AL Myers, DJ Sutton, A Andren, P Sajjakulnukit, L Zhang, ... Elife 11, e73245, 2022 | 37 | 2022 |
| The human type 2 diabetes-specific visceral adipose tissue proteome and transcriptome in obesity NJ Carruthers, C Strieder-Barboza, JA Caruso, CG Flesher, NA Baker, ... Scientific reports 11 (1), 17394, 2021 | 36 | 2021 |
| Therapeutic inhibition of the MDM2–p53 interaction prevents recurrence of adenoid cystic carcinomas F Nör, KA Warner, Z Zhang, GA Acasigua, AT Pearson, SA Kerk, ... Clinical cancer research 23 (4), 1036-1048, 2017 | 34 | 2017 |
| IL-6 inhibition with MEDI5117 decreases the fraction of head and neck cancer stem cells and prevents tumor recurrence KA Finkel, KA Warner, S Kerk, CR Bradford, SA McLean, ME Prince, ... Neoplasia 18 (5), 273-281, 2016 | 33 | 2016 |
| Microenvironmental ammonia enhances T cell exhaustion in colorectal cancer HN Bell, AK Huber, R Singhal, N Korimerla, RJ Rebernick, R Kumar, ... Cell metabolism 35 (1), 134-149. e6, 2023 | 29 | 2023 |
| Differential integrated stress response and asparagine production drive symbiosis and therapy resistance of pancreatic adenocarcinoma cells CJ Halbrook, G Thurston, S Boyer, C Anaraki, JA Jiménez, A McCarthy, ... Nature cancer 3 (11), 1386-1403, 2022 | 22 | 2022 |
| Ablation of cancer stem cells by therapeutic inhibition of the MDM2–p53 interaction in mucoepidermoid carcinoma A Andrews, K Warner, C Rodriguez-Ramirez, AT Pearson, F Nör, Z Zhang, ... Clinical Cancer Research 25 (5), 1588-1600, 2019 | 22 | 2019 |
| Colorectal cancer cells utilize autophagy to maintain mitochondrial metabolism for cell proliferation under nutrient stress SN Devenport, R Singhal, MD Radyk, JG Taranto, SA Kerk, B Chen, ... JCI insight 6 (14), 2021 | 21 | 2021 |
| Alkaline pH activates the transport activity of GLUT1 in L929 fibroblast cells SM Gunnink, SA Kerk, BD Kuiper, OD Alabi, DP Kuipers, RC Praamsma, ... Biochimie 99, 189-194, 2014 | 19 | 2014 |
