| Synthesis of Fluorophosphate Nucleotide Analogues and Their Characterization as Tools for 19F NMR Studies MR Baranowski, A Nowicka, AM Rydzik, M Warminski, R Kasprzyk, ... The Journal of organic chemistry 80 (8), 3982-3997, 2015 | 37 | 2015 |
| 2′-O-Methylation of the second transcribed nucleotide within the mRNA 5′ cap impacts the protein production level in a cell-specific manner and contributes to … K Drazkowska, R Tomecki, M Warminski, N Baran, D Cysewski, A Depaix, ... Nucleic acids research 50 (16), 9051-9071, 2022 | 29 | 2022 |
| Identification and evaluation of potential SARS-CoV-2 antiviral agents targeting mRNA cap guanine N7-Methyltransferase R Kasprzyk, TJ Spiewla, M Smietanski, S Golojuch, L Vangeel, ... Antiviral Research 193, 105142, 2021 | 24 | 2021 |
| Structural insights into the interaction of clinically relevant phosphorothioate mRNA cap analogs with translation initiation factor 4E reveal stabilization via electrostatic … M Warminski, J Kowalska, E Nowak, D Kubacka, R Tibble, R Kasprzyk, ... ACS Chemical Biology 16 (2), 334-343, 2021 | 19 | 2021 |
| 7-Methylguanosine monophosphate analogues with 5′-(1, 2, 3-triazoyl) moiety: Synthesis and evaluation as the inhibitors of cNIIIB nucleotidase M Kozarski, D Kubacka, BA Wojtczak, R Kasprzyk, MR Baranowski, ... Bioorganic & Medicinal Chemistry 26 (1), 191-199, 2018 | 17 | 2018 |
| Enzymatic assays to explore viral mRNA capping machinery R Kasprzyk, J Jemielity ChemBioChem 22 (23), 3236-3253, 2021 | 12 | 2021 |
| Acetylpyrene-labelled 7-methylguanine nucleotides: unusual fluorescence properties and application to decapping scavenger activity monitoring R Kasprzyk, J Kowalska, Z Wieczorek, M Szabelski, R Stolarski, ... Organic & Biomolecular Chemistry 14 (16), 3863-3868, 2016 | 12 | 2016 |
| Fluorescent Turn‐On Probes for the Development of Binding and Hydrolytic Activity Assays for mRNA Cap‐Recognizing Proteins R Kasprzyk, BJ Starek, S Ciechanowicz, D Kubacka, J Kowalska, ... Chemistry–A European Journal 25 (27), 6728-6740, 2019 | 10 | 2019 |
| Ebselen derivatives inhibit SARS-CoV-2 replication by inhibition of its essential proteins: PLpro and Mpro proteases, and nsp14 guanine N7-methyltransferase M Zmudzinski, W Rut, K Olech, J Granda, M Giurg, M Burda-Grabowska, ... Scientific reports 13 (1), 9161, 2023 | 9 | 2023 |
| Exploring the potential of phosphotriazole 5′ mRNA cap analogues as efficient translation initiators S Walczak, PJ Sikorski, R Kasprzyk, J Kowalska, J Jemielity Organic & Biomolecular Chemistry 16 (36), 6741-6748, 2018 | 9 | 2018 |
| Cellular delivery of dinucleotides by conjugation with small molecules: targeting translation initiation for anticancer applications N Kleczewska, PJ Sikorski, Z Warminska, L Markiewicz, R Kasprzyk, ... Chemical Science 12 (30), 10242-10251, 2021 | 7 | 2021 |
| N1-Propargylguanosine Modified mRNA Cap Analogs: Synthesis, reactivity, and applications to the study of cap-binding proteins M Kopcial, BA Wojtczak, R Kasprzyk, J Kowalska, J Jemielity Molecules 24 (10), 1899, 2019 | 7 | 2019 |
| Evaluation of carboxyfluorescein-labeled 7-methylguanine nucleotides as probes for studying cap-binding proteins by fluorescence anisotropy A Wojtczak, R Kasprzyk, M Warmiński, K Ubych, D Kubacka, PJ Sikorski, ... Scientific Reports 11 (1), 7687, 2021 | 6 | 2021 |
| Direct High‐Throughput Screening Assay for mRNA Cap Guanine‐N7 Methyltransferase Activity R Kasprzyk, M Fido, A Mamot, P Wanat, M Smietanski, M Kopcial, ... Chemistry–A European Journal 26 (49), 11266-11275, 2020 | 6 | 2020 |
| ExciTides: NTP-derived probes for monitoring pyrophosphatase activity based on excimer-to-monomer transitions P Wanat, R Kasprzyk, M Kopcial, PJ Sikorski, D Strzelecka, J Jemielity, ... Chemical communications 54 (70), 9773-9776, 2018 | 6 | 2018 |
| Exploring tryptamine conjugates as pronucleotides of phosphate-modified 7-methylguanine nucleotides targeting cap-dependent translation S Golojuch, M Kopcial, D Strzelecka, R Kasprzyk, N Baran, PJ Sikorski, ... Bioorganic & Medicinal Chemistry 28 (13), 115523, 2020 | 5 | 2020 |
| Fluorescence anisotropy assay with guanine nucleotides provides access to functional analysis of Gαi1 proteins A Pepanian, P Sommerfeld, R Kasprzyk, T Kühl, FA Binbay, C Hauser, ... Analytical Chemistry 94 (41), 14410-14418, 2022 | 2 | 2022 |
| Fluorescence-based activity screening assay reveals small molecule inhibitors of vaccinia virus mRNA decapping enzyme D9 M Bednarczyk, JK Peters, R Kasprzyk, J Starek, M Warminski, T Spiewla, ... ACS Chemical Biology 17 (6), 1460-1471, 2022 | 2 | 2022 |
| A desthiobiotin labelled NAD+ analogue to uncover Poly (ADP‐ribose) polymerase 1 protein targets S Rieth, D Spliesgar, J Orth, M Lehner, R Kasprzyk, F Stengel, A Marx ChemBioChem, e202300797, 2024 | | 2024 |
| Metody badania białek związanych z metabolizmem końca 5'mRNA oparte na nukleotydowych sondach molekularnych R Kasprzyk | | 2021 |
Jacek JemielityCentre of New Technologies, University of WarsawAdresse e-mail validée de biogeo.uw.edu.pl
