Timothy Pullen
Timothy Pullen
Adresse e-mail validée de kcl.ac.uk
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Pancreatic β-cell identity, glucose sensing and the control of insulin secretion
GA Rutter, TJ Pullen, DJ Hodson, A Martinez-Sanchez
Biochemical Journal 466 (2), 203-218, 2015
2442015
miR-29a and miR-29b contribute to pancreatic β-cell-specific silencing of monocarboxylate transporter 1 (Mct1)
TJ Pullen, G da Silva Xavier, G Kelsey, GA Rutter
Molecular and cellular biology 31 (15), 3182-3194, 2011
2262011
The mitochondrial Ca 2+ uniporter MCU is essential for glucose-induced ATP increases in pancreatic β-cells
AI Tarasov, F Semplici, MA Ravier, EA Bellomo, TJ Pullen, P Gilon, ...
PloS one 7 (7), e39722, 2012
1332012
Identification of genes selectively disallowed in the pancreatic islet
TJ Pullen, AM Khan, G Barton, SA Butcher, G Sun, GA Rutter
Islets 2 (2), 89-95, 2010
1042010
ADCY5 couples glucose to insulin secretion in human islets
DJ Hodson, RK Mitchell, L Marselli, TJ Pullen, SG Brias, F Semplici, ...
Diabetes 63 (9), 3009-3021, 2014
952014
Inside and outside of the trypanosome flagellum: a multifunctional organelle
P Bastin, TJ Pullen, FF Moreira-Leite, K Gull
Microbes and infection 2 (15), 1865-1874, 2000
952000
Protein transport and flagellum assembly dynamics revealed by analysis of the paralysed trypanosome mutant snl-1
P Bastin, TJ Pullen, T Sherwin, K Gull
Journal of Cell Science 112 (21), 3769-3777, 1999
921999
Protein targeting of an unusual, evolutionarily conserved adenylate kinase to a eukaryotic flagellum
TJ Pullen, ML Ginger, SJ Gaskell, K Gull
Molecular Biology of the Cell 15 (7), 3257-3265, 2004
852004
Overexpression of monocarboxylate transporter-1 (SLC16A1) in mouse pancreatic β-cells leads to relative hyperinsulinism during exercise
TJ Pullen, L Sylow, G Sun, AP Halestrap, EA Richter, GA Rutter
Diabetes 61 (7), 1719-1725, 2012
832012
The yeast CDC9 gene encodes both a nuclear and a mitochondrial form of DNA ligase I
M Willer, M Rainey, T Pullen, CJ Stirling
Current biology 9 (19), 1085-S1, 1999
791999
When less is more: the forbidden fruits of gene repression in the adult β‐cell
TJ Pullen, GA Rutter
Diabetes, Obesity and Metabolism 15 (6), 503-512, 2013
772013
P-selectin binds to the D′-D3 domains of von Willebrand factor in Weibel-Palade bodies
G Michaux, TJ Pullen, SL Haberichter, DF Cutler
Blood 107 (10), 3922-3924, 2006
722006
Intracellular positioning of isoforms explains an unusually large adenylate kinase gene family in the parasite Trypanosoma brucei
ML Ginger, ES Ngazoa, CA Pereira, TJ Pullen, M Kabiri, K Becker, K Gull, ...
Journal of Biological Chemistry 280 (12), 11781-11789, 2005
702005
Carbohydrate-responsive element-binding protein (ChREBP) is a negative regulator of ARNT/HIF-1β gene expression in pancreatic islet β-cells
NA Noordeen, TK Khera, G Sun, ER Longbottom, TJ Pullen, ...
Diabetes 59 (1), 153-160, 2010
692010
LKB1 and AMPK differentially regulate pancreatic β‐cell identity
M Kone, TJ Pullen, G Sun, M Ibberson, A Martinez‐Sanchez, S Sayers, ...
The FASEB Journal 28 (11), 4972-4985, 2014
652014
Chronic activation of γ2 AMPK induces obesity and reduces β cell function
A Yavari, CJ Stocker, S Ghaffari, ET Wargent, V Steeples, G Czibik, ...
Cell metabolism 23 (5), 821-836, 2016
622016
Decreased STARD10 Expression Is Associated with Defective Insulin Secretion in Humans and Mice
GR Carrat, M Hu, MS Nguyen-Tu, P Chabosseau, KJ Gaulton, ...
The American Journal of Human Genetics 100 (2), 238-256, 2017
412017
The transcription factor Pax6 is required for pancreatic β cell identity, glucose-regulated ATP synthesis, and Ca2+ dynamics in adult mice
RK Mitchell, MS Nguyen-Tu, P Chabosseau, RM Callingham, TJ Pullen, ...
Journal of Biological Chemistry 292 (21), 8892-8906, 2017
352017
Analysis of purified pancreatic islet beta and alpha cell transcriptomes reveals 11β-hydroxysteroid dehydrogenase (Hsd11b1) as a novel disallowed gene
TJ Pullen, MO Huising, GA Rutter
Frontiers in genetics 8, 41, 2017
342017
Nucleo-cytosolic shuttling of FoxO1 directly regulates mouse Ins2 but not Ins1 gene expression in pancreatic beta cells (MIN6)
G Meur, Q Qian, G da Silva Xavier, TJ Pullen, T Tsuboi, C McKinnon, ...
Journal of Biological Chemistry 286 (15), 13647-13656, 2011
322011
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