| Prostate cancer stem cells SH Lang, FM Frame, AT Collins The Journal of Pathology: A Journal of the Pathological Society of Great …, 2009 | 203 | 2009 |
| Low-temperature plasma treatment induces DNA damage leading to necrotic cell death in primary prostate epithelial cells AM Hirst, MS Simms, VM Mann, NJ Maitland, D O'connell, FM Frame British journal of cancer 112 (9), 1536-1545, 2015 | 201 | 2015 |
| Low temperature plasmas as emerging cancer therapeutics: the state of play and thoughts for the future AM Hirst, FM Frame, M Arya, NJ Maitland, D O’Connell Tumor Biology 37, 7021-7031, 2016 | 186 | 2016 |
| Apoptosis associated with deregulated E2F activity is dependent on E2F1 and Atm/Nbs1/Chk2 HA Rogoff, MT Pickering, FM Frame, ME Debatis, Y Sanchez, S Jones, ... Molecular and cellular biology 24 (7), 2968-2977, 2004 | 165 | 2004 |
| Inhibition of the PI3K/AKT/mTOR pathway activates autophagy and compensatory Ras/Raf/MEK/ERK signalling in prostate cancer DE Butler, C Marlein, HF Walker, FM Frame, VM Mann, MS Simms, ... Oncotarget 8 (34), 56698, 2017 | 125 | 2017 |
| Prostate cancer stem cells: do they have a basal or luminal phenotype? NJ Maitland, FM Frame, ES Polson, JL Lewis, AT Collins Hormones and Cancer 2, 47-61, 2011 | 122 | 2011 |
| Human cytomegalovirus IE1-72 activates ataxia telangiectasia mutated kinase and a p53/p21-mediated growth arrest response JP Castillo, FM Frame, HA Rogoff, MT Pickering, AD Yurochko, ... Journal of virology 79 (17), 11467-11475, 2005 | 85 | 2005 |
| An epigenetic reprogramming strategy to resensitize radioresistant prostate cancer cells C Peitzsch, M Cojoc, L Hein, I Kurth, K Mäbert, F Trautmann, B Klink, ... Cancer research 76 (9), 2637-2651, 2016 | 75 | 2016 |
| HDAC inhibitor confers radiosensitivity to prostate stem-like cells FM Frame, D Pellacani, AT Collins, MS Simms, VM Mann, GDD Jones, ... British journal of cancer 109 (12), 3023-3033, 2013 | 74 | 2013 |
| Cancer stem cells, models of study and implications of therapy resistance mechanisms FM Frame, NJ Maitland Human Cell Transformation: Role of Stem Cells and the Microenvironment, 105-118, 2012 | 70 | 2012 |
| Low temperature plasma: a novel focal therapy for localized prostate cancer? AM Hirst, FM Frame, NJ Maitland, D O’Connell BioMed research international 2014, 2014 | 64 | 2014 |
| E2F1 induces MRN foci formation and a cell cycle checkpoint response in human fibroblasts FM Frame, HA Rogoff, MT Pickering, WD Cress, TF Kowalik Oncogene 25 (23), 3258-3266, 2006 | 63 | 2006 |
| Regulation of the stem cell marker CD133 is independent of promoter hypermethylation in human epithelial differentiation and cancer D Pellacani, RJ Packer, FM Frame, EE Oldridge, PA Berry, MC Labarthe, ... Molecular cancer 10, 1-14, 2011 | 56 | 2011 |
| Differential cytotoxic activity of a novel palladium-based compound on prostate cell lines, primary prostate epithelial cells and prostate stem cells E Ulukaya, FM Frame, B Cevatemre, D Pellacani, H Walker, VM Mann, ... PloS one 8 (5), e64278, 2013 | 48 | 2013 |
| An internal polyadenylation signal substantially increases expression levels of lentivirus-delivered transgenes but has the potential to reduce viral titer in a promoter … S Hager, FM Frame, AT Collins, JE Burns, NJ Maitland Human gene therapy 19 (8), 840-850, 2008 | 41 | 2008 |
| DNA hypermethylation in prostate cancer is a consequence of aberrant epithelial differentiation and hyperproliferation D Pellacani, D Kestoras, AP Droop, FM Frame, PA Berry, MG Lawrence, ... Cell Death & Differentiation 21 (5), 761-773, 2014 | 37 | 2014 |
| Expression of nitric oxide synthase III (eNOS) mRNA by human skin cells: melanocytes but not keratinocytes express eNOS mRNA M Jackson, F Frame, R Weller, RC McKenzie Archives of dermatological research 290, 350-352, 1998 | 36 | 1998 |
| Effects on prostate cancer cells of targeting RNA polymerase III JL Petrie, C Swan, RM Ingram, FM Frame, AT Collins, H Dumay-Odelot, ... Nucleic Acids Research 47 (8), 3937-3956, 2019 | 32 | 2019 |
| Development and limitations of lentivirus vectors as tools for tracking differentiation in prostate epithelial cells FM Frame, S Hager, D Pellacani, MJ Stower, HF Walker, JE Burns, ... Experimental cell research 316 (19), 3161-3171, 2010 | 32 | 2010 |
| Tumor heterogeneity and therapy resistance-implications for future treatments of prostate cancer FM Frame, AR Noble, S Klein, HF Walker, R Suman, R Kasprowicz, ... J. Cancer Metastasis Treat 3 (12), 302, 2017 | 28 | 2017 |
