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Zharko Daniloski
Zharko Daniloski
Senior Scientist at Moderna Genomics
Adresse e-mail validée de modernatx.com
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Identification of required host factors for SARS-CoV-2 infection in human cells
Z Daniloski, TX Jordan, HH Wessels, DA Hoagland, S Kasela, M Legut, ...
Cell, 2021
5052021
The Spike D614G mutation increases SARS-CoV-2 infection of multiple human cell types
Z Daniloski, TX Jordan, JK Ilmain, X Guo, G Bhabha, BR TenOever, ...
Elife 10, e65365, 2021
316*2021
Massively parallel Cas13 screens reveal principles for guide RNA design
HH Wessels, A Méndez-Mancilla, X Guo, M Legut, Z Daniloski, ...
Nature biotechnology 38 (6), 722-727, 2020
2622020
A genome-scale screen for synthetic drivers of T cell proliferation
M Legut, Z Gajic, M Guarino, Z Daniloski, JA Rahman, X Xue, C Lu, L Lu, ...
Nature 603 (7902), 728-735, 2022
1002022
Integrative approach identifies SLC6A20 and CXCR6 as putative causal genes for the COVID-19 GWAS signal in the 3p21.31 locus
S Kasela, Z Daniloski, S Bollepalli, TX Jordan, BR tenOever, NE Sanjana, ...
Genome biology 22, 1-10, 2021
522021
High-throughput screens of PAM-flexible Cas9 variants for gene knockout and transcriptional modulation
M Legut, Z Daniloski, X Xue, D McKenzie, X Guo, HH Wessels, ...
Cell reports 30 (9), 2859-2868. e5, 2020
522020
SA1 binds directly to DNA through its unique AT-hook to promote sister chromatid cohesion at telomeres
KK Bisht, Z Daniloski, S Smith
Journal of cell science 126 (15), 3493-3503, 2013
512013
Discovery of target genes and pathways at GWAS loci by pooled single-cell CRISPR screens
JA Morris, C Caragine, Z Daniloski, J Domingo, T Barry, L Lu, K Davis, ...
Science 380 (6646), eadh7699, 2023
482023
Loss of Tumor Suppressor STAG2 Promotes Telomere Recombination and Extends the Replicative Lifespan of Normal Human Cells
Z Daniloski, S Smith
Cancer research 77 (20), 5530-5542, 2017
322017
Resolution of human ribosomal DNA occurs in anaphase, dependent on tankyrase 1, condensin II, and topoisomerase IIα
Z Daniloski, KK Bisht, B McStay, S Smith
Genes & development 33 (5-6), 276-281, 2019
282019
An autoimmune disease risk variant: A trans master regulatory effect mediated by IRF1 under immune stimulation?
M Brandt, S Kim-Hellmuth, M Ziosi, A Gokden, A Wolman, N Lam, ...
PLoS genetics 17 (7), e1009684, 2021
222021
Discovery of target genes and pathways of blood trait loci using pooled CRISPR screens and single cell RNA sequencing
JA Morris, Z Daniloski, J Domingo, T Barry, M Ziosi, DA Glinos, S Hao, ...
BioRxiv, 2021.04. 07.438882, 2021
162021
Expanding the scope of bacterial CRISPR activation with PAM-flexible dCas9 variants
C Kiattisewee, AV Karanjia, M Legut, Z Daniloski, SE Koplik, J Nelson, ...
ACS synthetic biology 11 (12), 4103-4112, 2022
72022
BR tenOever, NE Sanjana
Z Daniloski, TX Jordan, HH Wessels, DA Hoagland, S Kasela, M Legut, ...
Identification of required host factors for SARS-CoV-2 infection in human …, 2021
52021
Principles for rational Cas13d guide design
HH Wessels, A Méndez-Mancilla, X Guo, M Legut, Z Daniloski, ...
bioRxiv, 2019.12. 27.889089, 2019
32019
Compositions and methods for increasing efficiency of precise editing repair
N Sanjana, Z Daniloski
WO Patent WO2022251836A2, 2022
2022
Methods and compositions for inhibiting viral infection
NE Sanjana, Z Daniloski
WO Patent WO2022040319A2, 2022
2022
Recombinant crispr-cas9 nucleases with altered pam specificity
NE Sanjana, Z Daniloski, M Legut
US Patent App. 17/154,826, 2021
2021
The D614G mutation in SARS-CoV-2 Spike increases transduction of multiple human cell types (preprint)
Z Daniloski, TX Jordan, J Ilmain, X Guo, G Bhabha, NE Sanjana
2020
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