Ton N.M. Schumacher
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Signatures of mutational processes in human cancer
LB Alexandrov, S Nik-Zainal, DC Wedge, SAJR Aparicio, S Behjati, ...
Nature 500 (7463), 415-421, 2013
Mutational landscape determines sensitivity to PD-1 blockade in non–small cell lung cancer
NA Rizvi, MD Hellmann, A Snyder, P Kvistborg, V Makarov, JJ Havel, ...
Science 348 (6230), 124-128, 2015
Neoantigens in cancer immunotherapy
TN Schumacher, RD Schreiber
Science 348 (6230), 69-74, 2015
Mutations associated with acquired resistance to PD-1 blockade in melanoma
JM Zaretsky, A Garcia-Diaz, DS Shin, H Escuin-Ordinas, W Hugo, ...
New England Journal of Medicine 375 (9), 819-829, 2016
Checkpoint blockade cancer immunotherapy targets tumour-specific mutant antigens
MM Gubin, X Zhang, H Schuster, E Caron, JP Ward, T Noguchi, Y Ivanova, ...
Nature 515 (7528), 577-581, 2014
Synergism of Cytotoxic T Lymphocyte–Associated Antigen 4 Blockade and Depletion of Cd25+ Regulatory T Cells in Antitumor Therapy Reveals Alternative …
RPM Sutmuller, LM Van Duivenvoorde, A Van Elsas, TNM Schumacher, ...
The Journal of experimental medicine 194 (6), 823-832, 2001
Empty MHC class I molecules come out in the cold
HG Ljunggren, NJ Stam, C Öhlén, JJ Neefjes, P Höglund, MT Heemels, ...
Nature 346 (6283), 476-480, 1990
CD27 is required for generation and long-term maintenance of T cell immunity
J Hendriks, LA Gravestein, K Tesselaar, RAW van Lier, TNM Schumacher, ...
Nature immunology 1 (5), 433-440, 2000
Tumor exome analysis reveals neoantigen-specific T-cell reactivity in an ipilimumab-responsive melanoma
N van Rooij, MM van Buuren, D Philips, A Velds, M Toebes, B Heemskerk, ...
Journal of clinical oncology: official journal of the American Society of …, 2013
Science forum: the human cell atlas
A Regev, SA Teichmann, ES Lander, I Amit, C Benoist, E Birney, ...
Elife 6, e27041, 2017
CD40 activation in vivo overcomes peptide-induced peripheral cytotoxic T-lymphocyte tolerance and augments anti-tumor vaccine efficacy
L Diehl, AT den Boer, SP Schoenberger, EIH van der Voort, ...
Nature medicine 5 (7), 774-779, 1999
High-throughput epitope discovery reveals frequent recognition of neo-antigens by CD4+ T cells in human melanoma
C Linnemann, MM Van Buuren, L Bies, EME Verdegaal, R Schotte, ...
Nature medicine 21 (1), 81-85, 2015
Guidelines for the use of flow cytometry and cell sorting in immunological studies
A Cossarizza, HD Chang, A Radbruch, M Akdis, I Andrä, F Annunziato, ...
European journal of immunology 47 (10), 1584-1797, 2017
Direct binding of peptide to empty MHC class I molecules on intact cells and in vitro
TNM Schumacher, MT Heemels, JJ Neefjes, WM Kast, CJM Melief, ...
Cell 62 (3), 563-567, 1990
Generation of peptide–MHC class I complexes through UV-mediated ligand exchange
B Rodenko, M Toebes, SR Hadrup, WJE Van Esch, AM Molenaar, ...
Nature protocols 1 (3), 1120, 2006
The “cancer immunogram”
CU Blank, JB Haanen, A Ribas, TN Schumacher
Science 352 (6286), 658-660, 2016
Lethal graft-versus-host disease in mouse models of T cell receptor gene therapy
GM Bendle, C Linnemann, AI Hooijkaas, L Bies, MA de Witte, A Jorritsma, ...
Nature medicine 16 (5), 565-570, 2010
TAP1-dependent peptide translocation in vitro is ATP dependent and peptide selective
JC Shepherd, TNM Schumacher, PG Ashton-Rickardt, S Imaeda, ...
Cell 74 (3), 577-584, 1993
Parallel detection of antigen-specific T cell responses by combinatorial encoding of MHC multimers
RS Andersen, P Kvistborg, TM Frøsig, NW Pedersen, R Lyngaa, ...
Nature protocols 7 (5), 891-902, 2012
Immunotherapy through TCR gene transfer
HWHG Kessels, MC Wolkers, MD van den Boom, MA van den Valk, ...
Nature immunology 2 (10), 957-961, 2001
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