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Ieva Sutkeviciute
Ieva Sutkeviciute
Research Assistant Professor, University of Pittsburgh
Adresse e-mail validée de pitt.edu
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Année
Structure and dynamics of the active human parathyroid hormone receptor-1
LH Zhao, S Ma, I Sutkeviciute, DD Shen, XE Zhou, PW de Waal, CY Li, ...
Science 364 (6436), 148-153, 2019
1942019
A multivalent inhibitor of the DC-SIGN dependent uptake of HIV-1 and Dengue virus
N Varga, I Sutkeviciute, R Ribeiro-Viana, A Berzi, R Ramdasi, A Daghetti, ...
Biomaterials 35 (13), 4175-4184, 2014
1312014
Pseudosaccharide functionalized dendrimers as potent inhibitors of DC-SIGN dependent Ebola pseudotyped viral infection
J Luczkowiak, S Sattin, I Sutkeviciute, JJ Reina, M Sánchez-Navarro, ...
Bioconjugate chemistry 22 (7), 1354-1365, 2011
1172011
Structure of a glycomimetic ligand in the carbohydrate recognition domain of C-type lectin DC-SIGN. Structural requirements for selectivity and ligand design
M Thépaut, C Guzzi, I Sutkeviciute, S Sattin, R Ribeiro-Viana, N Varga, ...
Journal of the American Chemical Society 135 (7), 2518-2529, 2013
962013
A glycomimetic compound inhibits DC-SIGN-mediated HIV infection in cellular and cervical explant models
A Berzi, JJ Reina, R Ottria, I Sutkeviciute, P Antonazzo, ...
Aids 26 (2), 127-137, 2012
742012
Second generation of fucose-based DC-SIGN ligands: affinity improvement and specificity versus Langerin
M Andreini, D Doknic, I Sutkeviciute, JJ Reina, J Duan, E Chabrol, ...
Organic & biomolecular chemistry 9 (16), 5778-5786, 2011
742011
Selective targeting of dendritic cell‐specific intercellular adhesion molecule‐3‐grabbing nonintegrin (DC‐SIGN) with mannose‐based glycomimetics: synthesis and interaction …
N Varga, I Sutkeviciute, C Guzzi, J McGeagh, I Petit‐Haertlein, S Gugliotta, ...
Chemistry–A European Journal 19 (15), 4786-4797, 2013
702013
Structural insights into emergent signaling modes of G protein–coupled receptors
I Sutkeviciute, JP Vilardaga
Journal of Biological Chemistry 295 (33), 11626-11642, 2020
682020
Rational-differential design of highly specific glycomimetic ligands: targeting DC-SIGN and excluding langerin recognition
V Porkolab, E Chabrol, N Varga, S Ordanini, I Sutkevičiu̅tė, ...
ACS chemical biology 13 (3), 600-608, 2017
662017
PTH/PTHrP receptor signaling, allostery, and structures
I Sutkeviciute, LJ Clark, AD White, TJ Gardella, JP Vilardaga
Trends in Endocrinology & Metabolism 30 (11), 860-874, 2019
642019
Unique DC-SIGN clustering activity of a small glycomimetic: A lesson for ligand design
I Sutkeviciute, M Thépaut, S Sattin, A Berzi, J McGeagh, S Grudinin, ...
ACS chemical biology 9 (6), 1377-1385, 2014
602014
Spatial bias in cAMP generation determines biological responses to PTH type 1 receptor activation
AD White, KA Peña, LJ Clark, CS Maria, S Liu, FG Jean-Alphonse, JY Lee, ...
Science signaling 14 (703), eabc5944, 2021
482021
Ca2+ allostery in PTH-receptor signaling
AD White, F Fang, FG Jean-Alphonse, LJ Clark, HJ An, H Liu, Y Zhao, ...
Proceedings of the National Academy of Sciences 116 (8), 3294-3299, 2019
472019
Allosteric interactions in the parathyroid hormone GPCR–arrestin complex formation
LJ Clark, J Krieger, AD White, V Bondarenko, S Lei, F Fang, JY Lee, ...
Nature chemical biology 16 (10), 1096-1104, 2020
402020
Development of C-type lectin-oriented surfaces for high avidity glycoconjugates: towards mimicking multivalent interactions on the cell surface
V Porkolab, C Pifferi, I Sutkeviciute, S Ordanini, M Taouai, M Thepaut, ...
Organic & Biomolecular Chemistry 18 (25), 4763-4772, 2020
392020
Synthesis of a selective inhibitor of a fucose binding bacterial lectin from Burkholderia ambifaria
B Richichi, A Imberty, E Gillon, R Bosco, I Sutkeviciute, F Fieschi, C Nativi
Organic & Biomolecular Chemistry 11 (24), 4086-4094, 2013
372013
Transmission electron microscopy for the evaluation and optimization of crystal growth
HP Stevenson, G Lin, CO Barnes, I Sutkeviciute, T Krzysiak, SC Weiss, ...
Acta Crystallographica Section D: Structural Biology 72 (5), 603-615, 2016
342016
Polyvalent C-glycomimetics based on l-fucose or d-mannose as potent DC-SIGN antagonists
B Bertolotti, I Sutkeviciute, M Ambrosini, R Ribeiro-Viana, J Rojo, ...
Organic & Biomolecular Chemistry 15 (18), 3995-4004, 2017
262017
Synthesis and characterization of linker‐armed fucose‐based glycomimetics
D Doknic, M Abramo, I Sutkeviciute, A Reinhardt, C Guzzi, MK Schlegel, ...
European Journal of Organic Chemistry 2013 (24), 5303-5314, 2013
242013
Detection and quantitative analysis of two independent binding modes of a small ligand responsible for DC-SIGN clustering
C Guzzi, P Alfarano, I Sutkeviciute, S Sattin, R Ribeiro-Viana, F Fieschi, ...
Organic & Biomolecular Chemistry 14 (1), 335-344, 2016
192016
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