Suivre
Blanton Tolbert
Blanton Tolbert
Professor of Biochemistry and Biophysics, UPenn
Adresse e-mail validée de pennmedicine.upenn.edu
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Année
Direct Determination of Thiol pKa by Isothermal Titration Microcalorimetry
SG Tajc, BS Tolbert, R Basavappa, BL Miller
Journal of the American Chemical Society 126 (34), 10508-10509, 2004
2072004
Secondary structure determination of conserved SARS-CoV-2 RNA elements by NMR spectroscopy
A Wacker, JE Weigand, SR Akabayov, N Altincekic, JK Bains, ...
Nucleic acids research 48 (22), 12415-12435, 2020
1342020
Major groove width variations in RNA structures determined by NMR and impact of 13C residual chemical shift anisotropy and 1H–13C residual dipolar coupling …
BS Tolbert, Y Miyazaki, S Barton, B Kinde, P Starck, R Singh, A Bax, ...
Journal of biomolecular NMR 47, 205-219, 2010
932010
HnRNP A1 alters the structure of a conserved enterovirus IRES domain to stimulate viral translation
M Tolbert, CE Morgan, M Pollum, CE Crespo-Hernández, ML Li, G Brewer, ...
Journal of molecular biology 429 (19), 2841-2858, 2017
782017
IRES-targeting small molecule inhibits enterovirus 71 replication via allosteric stabilization of a ternary complex
J Davila-Calderon, NN Patwardhan, LY Chiu, A Sugarman, Z Cai, ...
Nature communications 11 (1), 4775, 2020
772020
Structure of a conserved retroviral RNA packaging element by NMR spectroscopy and cryo-electron tomography
Y Miyazaki, RN Irobalieva, BS Tolbert, A Smalls-Mantey, K Iyalla, ...
Journal of molecular biology 404 (5), 751-772, 2010
762010
Rules of RNA specificity of hnRNP A1 revealed by global and quantitative analysis of its affinity distribution
N Jain, HC Lin, CE Morgan, ME Harris, BS Tolbert
Proceedings of the National Academy of Sciences 114 (9), 2206-2211, 2017
642017
High-affinity interaction of hnRNP A1 with conserved RNA structural elements is required for translation and replication of enterovirus 71
JD Levengood, M Tolbert, ML Li, BS Tolbert
RNA biology 10 (7), 1136-1145, 2013
612013
Regio‐selective chemical‐enzymatic synthesis of pyrimidine nucleotides facilitates RNA structure and dynamics studies
LJ Alvarado, RM LeBlanc, AP Longhini, SC Keane, N Jain, ZF Yildiz, ...
ChemBioChem 15 (11), 1573-1577, 2014
522014
Evidence for Direct Binding between HetR from Anabaena sp. PCC 7120 and PatS-5
EA Feldmann, S Ni, ID Sahu, CH Mishler, DD Risser, JL Murakami, ...
Biochemistry 50 (43), 9212-9224, 2011
502011
The first crystal structure of the UP1 domain of hnRNP A1 bound to RNA reveals a new look for an old RNA binding protein
CE Morgan, JL Meagher, JD Levengood, J Delproposto, C Rollins, ...
Journal of molecular biology 427 (20), 3241-3257, 2015
492015
Enterovirus A71 vaccines
ML Li, SR Shih, BS Tolbert, G Brewer
Vaccines 9 (3), 199, 2021
472021
The Active Site Cysteine of Ubiquitin-Conjugating Enzymes Has a Significantly Elevated pKa:  Functional Implications
BS Tolbert, SG Tajc, H Webb, J Snyder, JE Nielsen, BL Miller, ...
Biochemistry 44 (50), 16385-16391, 2005
432005
EV71 3C protease induces apoptosis by cleavage of hnRNP A1 to promote apaf-1 translation
ML Li, JY Lin, BS Chen, KF Weng, SR Shih, JD Calderon, BS Tolbert, ...
PloS one 14 (9), e0221048, 2019
412019
NMR Structures of (rGCUGAGGCU)2 and (rGCGGAUGCU)2:  Probing the Structural Features That Shape the Thermodynamic Stability of GA Pairs,
BS Tolbert, SD Kennedy, SJ Schroeder, TR Krugh, DH Turner
Biochemistry 46 (6), 1511-1522, 2007
412007
Application of bioconjugation chemistry on biosensor fabrication for detection of TAR-DNA binding protein 43
Y Dai, C Wang, LY Chiu, K Abbasi, BS Tolbert, G Sauvé, Y Yen, CC Liu
Biosensors and Bioelectronics 117, 60-67, 2018
402018
RNA Internal loops with tandem AG pairs: the structure of the 5′ G AG U/3′ U GA G loop can be dramatically different from others, including 5′ A AG U/3′ U GA A
NB Hammond, BS Tolbert, R Kierzek, DH Turner, SD Kennedy
Biochemistry 49 (27), 5817-5827, 2010
402010
Amilorides inhibit SARS-CoV-2 replication in vitro by targeting RNA structures
M Zafferani, C Haddad, L Luo, J Davila-Calderon, LY Chiu, CS Mugisha, ...
Science advances 7 (48), eabl6096, 2021
382021
Solution structure of the HIV-1 exon splicing silencer 3
JD Levengood, C Rollins, CHJ Mishler, CA Johnson, G Miner, P Rajan, ...
Journal of molecular biology 415 (4), 680-698, 2012
362012
Idiosyncrasies of hnRNP A1-RNA recognition: Can binding mode influence function
JD Levengood, BS Tolbert
Seminars in cell & developmental biology 86, 150-161, 2019
322019
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