Argyris Politis
Argyris Politis
Group Leader, EPSRC Research Fellow, University of Manchester
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Mass spectrometry of intact V-type ATPases reveals bound lipids and the effects of nucleotide binding
M Zhou, N Morgner, NP Barrera, A Politis, SC Isaacson, D Matak-Vinković, ...
Science 334 (6054), 380-385, 2011
Charge-state dependent compaction and dissociation of protein complexes: insights from ion mobility and molecular dynamics
Z Hall, A Politis, MF Bush, LJ Smith, CV Robinson
Journal of the American Chemical Society 134 (7), 3429-3438, 2012
Structure of the CRISPR interference complex CSM reveals key similarities with cascade
C Rouillon, M Zhou, J Zhang, A Politis, V Beilsten-Edmands, G Cannone, ...
Molecular cell 52 (1), 124-134, 2013
A mass spectrometry–based hybrid method for structural modeling of protein complexes
A Politis, F Stengel, Z Hall, H Hernández, A Leitner, T Walzthoeni, ...
Nature methods 11 (4), 403-406, 2014
Mass spectrometry reveals synergistic effects of nucleotides, lipids, and drugs binding to a multidrug resistance efflux pump
J Marcoux, SC Wang, A Politis, E Reading, J Ma, PC Biggin, M Zhou, ...
Proceedings of the National Academy of Sciences 110 (24), 9704-9709, 2013
Comparative cross-linking and mass spectrometry of an intact F-type ATPase suggest a role for phosphorylation
C Schmidt, M Zhou, H Marriott, N Morgner, A Politis, CV Robinson
Nature communications 4 (1), 1-11, 2013
Integrating ion mobility mass spectrometry with molecular modelling to determine the architecture of multiprotein complexes
A Politis, AY Park, SJ Hyung, D Barsky, BT Ruotolo, CV Robinson
PloS one 5 (8), e12080, 2010
Structural modeling of heteromeric protein complexes from disassembly pathways and ion mobility-mass spectrometry
Z Hall, A Politis, CV Robinson
Structure 20 (9), 1596-1609, 2012
Subunit architecture of multiprotein assemblies determined using restraints from gas-phase measurements
TL Pukala, BT Ruotolo, M Zhou, A Politis, R Stefanescu, JA Leary, ...
Structure 17 (9), 1235-1243, 2009
Direct protein-lipid interactions shape the conformational landscape of secondary transporters
C Martens, M Shekhar, AJ Borysik, AM Lau, E Reading, E Tajkhorshid, ...
Nature communications 9 (1), 1-12, 2018
Numerical modeling of simulated blood flow in idealized composite arterial coronary grafts: Steady state simulations
AK Politis, GP Stavropoulos, MN Christolis, FG Panagopoulos, ...
Journal of Biomechanics 40 (5), 1125-1136, 2007
Ion mobility–mass spectrometry of a rotary ATPase reveals ATP-induced reduction in conformational flexibility
M Zhou, A Politis, RB Davies, I Liko, KJ Wu, AG Stewart, D Stock, ...
Nature chemistry 6 (3), 208-215, 2014
Interrogating membrane protein conformational dynamics within native lipid compositions
E Reading, Z Hall, C Martens, T Haghighi, H Findlay, Z Ahdash, A Politis, ...
Angewandte Chemie International Edition 56 (49), 15654-15657, 2017
Ion mobility mass spectrometry of two tetrameric membrane protein complexes reveals compact structures and differences in stability and packing
SC Wang, A Politis, N Di Bartolo, VN Bavro, SJ Tucker, PJ Booth, ...
Journal of the American Chemical Society 132 (44), 15468-15470, 2010
Numerical modelling of simulated blood flow in idealized composite arterial coronary grafts: Transient flow
AK Politis, GP Stavropoulos, MN Christolis, PG Panagopoulos, ...
Journal of Biomechanics 41 (1), 25-39, 2008
Structural lipids enable the formation of functional oligomers of the eukaryotic purine symporter UapA
E Pyle, AC Kalli, S Amillis, Z Hall, AM Lau, AC Hanyaloglu, G Diallinas, ...
Cell chemical biology 25 (7), 840-848. e4, 2018
Mass spectrometry defines the C-terminal dimerization domain and enables modeling of the structure of full-length OmpA
J Marcoux, A Politis, D Rinehart, DP Marshall, MI Wallace, LK Tamm, ...
Structure 22 (5), 781-790, 2014
Integrative modelling coupled with ion mobility mass spectrometry reveals structural features of the clamp loader in complex with single-stranded DNA binding protein
A Politis, AY Park, Z Hall, BT Ruotolo, CV Robinson
Journal of molecular biology 425 (23), 4790-4801, 2013
Specific cardiolipin–SecY interactions are required for proton-motive force stimulation of protein secretion
RA Corey, E Pyle, WJ Allen, DW Watkins, M Casiraghi, B Miroux, ...
Proceedings of the National Academy of Sciences 115 (31), 7967-7972, 2018
Mass spectrometry reveals stable modules in holo and apo RNA polymerases I and III
LA Lane, C Fernández-Tornero, M Zhou, N Morgner, D Ptchelkine, ...
Structure 19 (1), 90-100, 2011
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