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Jeffrey West
Jeffrey West
Integrated Mathematical Oncology, Moffitt Cancer Center
Adresse e-mail validée de moffitt.org - Page d'accueil
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Towards multi-drug adaptive therapy
J West, L You, J Zhang, RA Gatenby, JS Brown, PK Newton, ...
Cancer Research, 2020
1932020
Turnover modulates the need for a cost of resistance in adaptive therapy
MAR Strobl, J West, Y Viossat, M Damaghi, M Robertson-Tessi, JS Brown, ...
Cancer Research 81 (4), 1135-1147, 2021
1112021
The harsh microenvironment in early breast cancer selects for a Warburg phenotype
M Damaghi, J West, M Robertson-Tessi, L Xu, MC Ferrall-Fairbanks, ...
Proceedings of the National Academy of Sciences 118 (3), e2011342118, 2021
1102021
Multidrug Cancer Therapy in Metastatic Castrate-Resistant Prostate Cancer: An Evolution-Based Strategy
JB West, MN Dinh, JS Brown, J Zhang, AR Anderson, RA Gatenby
Clinical Cancer Research 25 (14), 4413-4421, 2019
1032019
Hybrid Automata Library: A flexible platform for hybrid modeling with real-time visualization
RR Bravo, E Baratchart, J West, RO Schenck, AK Miller, J Gallaher, ...
PLoS Computational Biology 16 (3), e1007635, 2020
94*2020
Normal tissue architecture determines the evolutionary course of cancer
J West, RO Schenck, C Gatenbee, M Robertson-Tessi, ARA Anderson
Nature Communications 12 (1), 1-9, 2021
78*2021
Capitalizing on competition: An evolutionary model of competitive release in metastatic castration resistant prostate cancer treatment
J West, Y Ma, PK Newton
Journal of Theoretical Biology 455, 249-260, 2018
71*2018
Cellular interactions constrain tumor growth
J West, PK Newton
Proceedings of the National Academy of Sciences 116 (6), 1918-1923, 2019
692019
Spatial structure impacts adaptive therapy by shaping intra-tumoral competition
MAR Strobl, J Gallaher, J West, M Robertson-Tessi, PK Maini, ...
Communications medicine 2 (1), 46, 2022
602022
An evolutionary model of tumor cell kinetics and the emergence of molecular heterogeneity driving Gompertzian growth
J West, Z Hasnain, P Macklin, PK Newton
SIAM Review 58 (4), 716-736, 2016
552016
The prisoner’s dilemma as a cancer model
J West, Z Hasnain, J Mason, PK Newton
Convergent Science Physical Oncology 2 (3), 035002, 2016
492016
Chemotherapeutic dose scheduling based on tumor growth rates provides a case for low-dose metronomic high-entropy therapies
J West, PK Newton
Cancer Research 77 (23), 6717-6728, 2017
452017
Agent-based methods facilitate integrative science in cancer
J West, M Robertson-Tessi, ARA Anderson
Trends in cell biology 33 (4), 300-311, 2023
402023
A survey of open questions in adaptive therapy: Bridging mathematics and clinical translation
J West, F Adler, J Gallaher, M Strobl, R Brady-Nicholls, J Brown, ...
Elife 12, e84263, 2023
392023
Immunosuppressive niche engineering at the onset of human colorectal cancer
CD Gatenbee, AM Baker, RO Schenck, M Strobl, J West, MP Neves, ...
Nature Communications 13 (1), 1798, 2022
39*2022
The immune checkpoint kick start: Optimization of neoadjuvant combination therapy using game theory
J West, M Robertson-Tessi, K Luddy, DS Park, DFK Williamson, ...
JCO Clinical Cancer Informatics 3, 1-12, 2019
302019
Working with convex responses: Antifragility from finance to oncology
NN Taleb, J West
Entropy 25 (2), 343, 2023
202023
Treatment of evolving cancers will require dynamic decision support
MAR Strobl, J Gallaher, M Robertson-Tessi, J West, ARA Anderson
Annals of Oncology 34 (10), 867-884, 2023
192023
Feasibility of an evolutionary tumor board for generating novel personalized therapeutic strategies
M Robertson-Tessi, JS Brown, MI Poole, M Johnson, A Marusyk, ...
MedRxiv, 2023.01. 18.23284628, 2023
122023
Intermetastatic and intrametastatic heterogeneity shapes adaptive therapy cycling dynamics
J Gallaher, M Strobl, J West, R Gatenby, J Zhang, M Robertson-Tessi, ...
Cancer Research 83 (16), 2775-2789, 2023
11*2023
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