| Development and validation of a clinical cancer genomic profiling test based on massively parallel DNA sequencing GM Frampton, A Fichtenholtz, GA Otto, K Wang, SR Downing, J He, ... Nature biotechnology 31 (11), 1023-1031, 2013 | 2160 | 2013 |
| Activation of MET via diverse exon 14 splicing alterations occurs in multiple tumor types and confers clinical sensitivity to MET inhibitors GM Frampton, SM Ali, M Rosenzweig, J Chmielecki, X Lu, TM Bauer, ... Cancer discovery 5 (8), 850-859, 2015 | 731 | 2015 |
| A computational approach to distinguish somatic vs. germline origin of genomic alterations from deep sequencing of cancer specimens without a matched normal JX Sun, Y He, E Sanford, M Montesion, GM Frampton, S Vignot, JC Soria, ... PLoS computational biology 14 (2), e1005965, 2018 | 229 | 2018 |
| A novel next-generation sequencing approach to detecting microsatellite instability and pan-tumor characterization of 1000 microsatellite instability–high cases in 67,000 … SE Trabucco, K Gowen, SL Maund, E Sanford, DA Fabrizio, MJ Hall, ... The Journal of Molecular Diagnostics 21 (6), 1053-1066, 2019 | 178 | 2019 |
| Genomic alterations observed in colitis-associated cancers are distinct from those found in sporadic colorectal cancers and vary by type of inflammatory bowel disease R Yaeger, MA Shah, VA Miller, JR Kelsen, K Wang, ZJ Heins, JS Ross, ... Gastroenterology 151 (2), 278-287. e6, 2016 | 178 | 2016 |
| Comprehensive Genomic Profiling Identifies a Subset of Crizotinib-Responsive ALK-Rearranged Non-Small Cell Lung Cancer Not Detected by Fluorescence In … SM Ali, T Hensing, AB Schrock, J Allen, E Sanford, K Gowen, A Kulkarni, ... The oncologist 21 (6), 762-770, 2016 | 139 | 2016 |
| Enrichment of targetable mutations in the relapsed neuroblastoma genome OM Padovan-Merhar, P Raman, I Ostrovnaya, K Kalletla, KR Rubnitz, ... PLoS genetics 12 (12), e1006501, 2016 | 128 | 2016 |
| Identification and characterization of RET fusions in advanced colorectal cancer AF Le Rolle, SJ Klempner, CR Garrett, T Seery, EM Sanford, ... Oncotarget 6 (30), 28929, 2015 | 122 | 2015 |
| Activation of MET via diverse exon 14 splicing alterations occurs in multiple tumor types and confers clinical sensitivity to MET inhibitors. Cancer Discov. 2015; 5: 850–859 … GM Frampton, SM Ali, M Rosenzweig, J Chmielecki, X Lu, TM Bauer, ... Go to original source... Go to PubMed, 2015 | 115 | 2015 |
| Comprehensive genomic profiling of anal squamous cell carcinoma reveals distinct genomically defined classes JH Chung, E Sanford, A Johnson, SJ Klempner, AB Schrock, NA Palma, ... Annals of Oncology 27 (7), 1336-1341, 2016 | 92 | 2016 |
| Prospective comprehensive genomic profiling of advanced gastric carcinoma cases reveals frequent clinically relevant genomic alterations and new routes for targeted therapies SM Ali, EM Sanford, SJ Klempner, DA Rubinson, K Wang, NA Palma, ... The oncologist 20 (5), 499-507, 2015 | 81 | 2015 |
| HER2-overexpressing breast cancers amplify FGFR signaling upon acquisition of resistance to dual therapeutic blockade of HER2 AB Hanker, JT Garrett, MV Estrada, PD Moore, PG Ericsson, JP Koch, ... Clinical Cancer Research 23 (15), 4323-4334, 2017 | 80 | 2017 |
| Patient-derived xenotransplants can recapitulate the genetic driver landscape of acute leukemias K Wang, M Sanchez-Martin, X Wang, KM Knapp, R Koche, L Vu, ... Leukemia 31 (1), 151-158, 2017 | 76 | 2017 |
| Comprehensive genomic profiling of advanced penile carcinoma suggests a high frequency of clinically relevant genomic alterations SM Ali, SK Pal, K Wang, NA Palma, E Sanford, M Bailey, J He, JA Elvin, ... The oncologist 21 (1), 33-39, 2016 | 74 | 2016 |
| Gene networks with transcriptional bursting recapitulate rare transient coordinated high expression states in cancer L Schuh, M Saint-Antoine, EM Sanford, BL Emert, A Singh, C Marr, A Raj, ... Cell systems 10 (4), 363-378. e12, 2020 | 51 | 2020 |
| Antitumor response of VEGFR2-and VEGFR3-amplified angiosarcoma to pazopanib V Ravi, EM Sanford, WL Wang, JS Ross, N Ramesh, A Futreal, S Patel, ... Journal of the National Comprehensive Cancer Network 14 (5), 499-502, 2016 | 40 | 2016 |
| The clinical use of genomic profiling to distinguish intrapulmonary metastases from synchronous primaries in non–small-cell lung cancer: a mini-review SJ Klempner, SHI Ou, DB Costa, PA VanderLaan, EM Sanford, A Schrock, ... Clinical lung cancer 16 (5), 334-339. e1, 2015 | 31 | 2015 |
| Changes in chromatin accessibility are not concordant with transcriptional changes for single‐factor perturbations K Kiani, EM Sanford, Y Goyal, A Raj Molecular systems biology 18 (9), e10979, 2022 | 29 | 2022 |
| Evaluation of microsatellite instability (MSI) status in 11,573 diverse solid tumors using comprehensive genomic profiling (CGP). MJ Hall, K Gowen, EM Sanford, JA Elvin, SM Ali, J Kaczmar, E White, ... Journal of Clinical Oncology 34 (15_suppl), 1523-1523, 2016 | 22 | 2016 |
| Evaluation of microsatellite instability (MSI) status in gastrointestinal (GI) tumor samples tested with comprehensive genomic profiling (CGP). MJ Hall, K Gowen, EM Sanford, SM Ali, J Kaczmar, VA Miller, P Stephens, ... Journal of Clinical Oncology 34 (4_suppl), 528-528, 2016 | 14 | 2016 |
