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Martin Zoche
Martin Zoche
Director Molecular Tumor Profiling, Universityhospital Zurich
Adresse e-mail validée de usz.ch
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Calmodulin controls the rod photoreceptor CNG channel through an unconventional binding site in the N‐terminus of the β‐subunit
D Weitz, M Zoche, F Müller, M Beyermann, HG Körschen, UB Kaupp, ...
The EMBO Journal, 1998
1321998
Harmonization and standardization of panel-based tumor mutational burden measurement: real-world results and recommendations of the quality in pathology study
A Stenzinger, V Endris, J Budczies, S Merkelbach-Bruse, D Kazdal, ...
Journal of Thoracic Oncology 15 (7), 1177-1189, 2020
972020
The Tumor Profiler Study: integrated, multi-omic, functional tumor profiling for clinical decision support
A Irmisch, X Bonilla, S Chevrier, KV Lehmann, F Singer, NC Toussaint, ...
Cancer Cell 39 (3), 288-293, 2021
882021
Distinct molecular recognition of calmodulin-binding sites in the neuronal and macrophage nitric oxide synthases: a surface plasmon resonance study
M Zoche, M Bienert, M Beyermann, KW Koch
Biochemistry 35 (26), 8742-8747, 1996
561996
STRN-ALK rearranged malignant peritoneal mesothelioma with dramatic response following ceritinib treatment
JH Rüschoff, E Gradhand, A Kahraman, H Rees, JL Ferguson, ...
JCO precision oncology 3, 2019
482019
Trithiocarbonates—Exploration of a new head group for HDAC inhibitors
F Dehmel, T Ciossek, T Maier, S Weinbrenner, B Schmidt, M Zoche, ...
Bioorganic & medicinal chemistry letters 17 (17), 4746-4752, 2007
462007
Ligand sensitivity of the α2 subunit from the bovine cone cGMP-gated channel is modulated by protein kinase C but not by calmodulin
F Müller, M Vantler, D Weitz, E Eismann, M Zoche, KW Koch, UB Kaupp
The Journal of Physiology 532 (Pt 2), 399, 2001
402001
Genomic landscape of pleural and peritoneal mesothelioma tumours
S Hiltbrunner, Z Fleischmann, ES Sokol, M Zoche, E Felley-Bosco, ...
British Journal of Cancer 127 (11), 1997-2005, 2022
362022
Clonal hematopoiesis in hospitalized elderly patients with COVID-19
E Hameister, SM Stolz, Y Fuhrer, F Thienemann, DJ Schaer, J Nemeth, ...
Hemasphere 4 (4), e453, 2020
242020
Purified retinal nitric oxide synthase enhances ADP‐ribosylation of rod outer segment proteins
M Zoche, KW Koch
FEBS letters 357 (2), 178-182, 1995
231995
Introduction of a Phosphate at Serine741 of the Calmodulin-Binding Domain of the Neuronal Nitric Oxide Synthase (NOS-I) Prevents Binding of Calmodulin
M Zoche, M Beyermann, KW Koch
Walter de Gruyter, Berlin/New York 378 (8), 851-858, 1997
201997
Benzofuran derivatives
C Schmeck, U Müller, G Schmidt, J Pernerstorfer, H Bischoff, ...
US Patent 7,015,246, 2006
122006
Clinicopathological and genomic profiles of atypical fibroxanthoma and pleomorphic dermal sarcoma identify overlapping signatures with a high mutational burden
M Ak, A Kahraman, FM Arnold, P Turko, MP Levesque, M Zoche, ...
Genes 12 (7), 974, 2021
102021
Targeting Secondary and Tertiary Resistance to BRAF Inhibition in BRAF V600E-Mutated Metastatic Colorectal Cancer.
D Akhoundova Sanoyan, H Pietge, S Hussung, M Kiessling, C Britschgi, ...
JCO precision oncology 5, 1082-1087, 2021
102021
Comparison of calling pipelines for whole genome sequencing: an empirical study demonstrating the importance of mapping and alignment
RO Betschart, A Thiéry, D Aguilera-Garcia, M Zoche, H Moch, ...
Scientific Reports 12 (1), 21502, 2022
92022
ROS1 genomic rearrangements are rare actionable drivers in microsatellite stable colorectal cancer
D Akhoundova, S Hussung, S Sivakumar, A Töpfer, M Rechsteiner, ...
International journal of cancer 151 (12), 2161-2171, 2022
72022
Molecular and immunophenotypic characterization of SMARCB1 (INI1)-deficient intrathoracic Neoplasms
M Haberecker, MM Bühler, AP Mendieta, R Guggenberger, F Arnold, ...
Modern Pathology 35 (12), 1860-1869, 2022
72022
Unravelling homologous recombination repair deficiency and therapeutic opportunities in soft tissue and bone sarcoma
L Planas‐Paz, A Pliego‐Mendieta, C Hagedorn, D Aguilera‐Garcia, ...
EMBO molecular medicine 15 (4), e16863, 2023
42023
Prognostic impact of tumour mutational burden in resected stage I and II lung adenocarcinomas from a European Thoracic Oncology Platform Lungscape cohort
L Bubendorf, M Zoche, U Dafni, JH Rüschoff, SS Prince, N Marti, ...
Lung Cancer 174, 27-35, 2022
42022
Acquired resistance to anti-PD1 therapy in patients with NSCLC associates with immunosuppressive T cell phenotype
S Hiltbrunner, L Cords, S Kasser, SN Freiberger, S Kreutzer, ...
Nature Communications 14 (1), 5154, 2023
32023
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