Suivre
Elda Cannavo
Elda Cannavo
Research scientist Institute for Research in Biomedicine, IRB, Bellinzona, Switzerland
Adresse e-mail validée de irb.usi.ch
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DNA end resection by Dna2–Sgs1–RPA and its stimulation by Top3–Rmi1 and Mre11–Rad50–Xrs2
P Cejka, E Cannavo, P Polaczek, T Masuda-Sasa, S Pokharel, ...
Nature 467 (7311), 112-116, 2010
5062010
Sae2 promotes dsDNA endonuclease activity within Mre11–Rad50–Xrs2 to resect DNA breaks
E Cannavo, P Cejka
Nature 514 (7520), 122-125, 2014
4792014
Deficiency of FANCD2-associated nuclease KIAA1018/FAN1 sensitizes cells to interstrand crosslinking agents
K Kratz, B Schöpf, S Kaden, A Sendoel, R Eberhard, C Lademann, ...
Cell 142 (1), 77-88, 2010
3282010
Phosphorylated CtIP functions as a co-factor of the MRE11-RAD50-NBS1 endonuclease in DNA end resection
R Anand, L Ranjha, E Cannavo, P Cejka
Molecular cell 64 (5), 940-950, 2016
3232016
Methylation-induced G2/M arrest requires a full complement of the mismatch repair protein hMLH1
P Cejka, L Stojic, N Mojas, AM Russell, K Heinimann, E Cannavó, ...
The EMBO journal 22 (9), 2245-2254, 2003
2412003
Expression of the MutL homologue hMLH3 in human cells and its role in DNA mismatch repair
E Cannavo, G Marra, J Sabates-Bellver, M Menigatti, SM Lipkin, F Fischer, ...
Cancer research 65 (23), 10759-10766, 2005
1822005
Characterization of the interactome of the human MutL homologues MLH1, PMS1, and PMS2
E Cannavo, B Gerrits, G Marra, R Schlapbach, J Jiricny
Journal of Biological Chemistry 282 (5), 2976-2986, 2007
1682007
Relationship of DNA degradation by Saccharomyces cerevisiae exonuclease 1 and its stimulation by RPA and Mre11-Rad50-Xrs2 to DNA end resection
E Cannavo, P Cejka, SC Kowalczykowski
Proceedings of the National Academy of Sciences 110 (18), E1661-E1668, 2013
1542013
Physiological protein blocks direct the Mre11–Rad50–Xrs2 and Sae2 nuclease complex to initiate DNA end resection
G Reginato, E Cannavo, P Cejka
Genes & development 31 (23-24), 2325-2330, 2017
1292017
Regulation of the MLH1–MLH3 endonuclease in meiosis
E Cannavo, A Sanchez, R Anand, L Ranjha, J Hugener, C Adam, ...
Nature 586 (7830), 618-622, 2020
972020
Xrs2 dependent and independent functions of the Mre11-Rad50 complex
J Oh, A Al-Zain, E Cannavo, P Cejka, LS Symington
Molecular cell 64 (2), 405-415, 2016
812016
Regulatory control of DNA end resection by Sae2 phosphorylation
E Cannavo, D Johnson, SN Andres, VM Kissling, JK Reinert, V Garcia, ...
Nature communications 9 (1), 4016, 2018
772018
In vitro antitumour activity of resveratrol in human melanoma cells sensitive or resistant to temozolomide
MP Fuggetta, S D'Atri, G Lanzilli, M Tricarico, E Cannavò, G Zambruno, ...
Melanoma Research 14 (3), 189-196, 2004
652004
Stepwise 5′ DNA end-specific resection of DNA breaks by the Mre11-Rad50-Xrs2 and Sae2 nuclease ensemble
E Cannavo, G Reginato, P Cejka
Proceedings of the National Academy of Sciences 116 (12), 5505-5513, 2019
592019
High expression of the mismatch repair protein MSH6 is associated with poor patient survival in melanoma
E Alvino, F Passarelli, E Cannavò, C Fortes, S Mastroeni, S Caporali, ...
American journal of clinical pathology 142 (1), 121-132, 2014
292014
Analysis of multiply spliced transcripts in lymphoid tissue reservoirs of rhesus macaques infected with RT-SHIV during HAART
JD Deere, RC Kauffman, E Cannavo, J Higgins, A Villalobos, L Adamson, ...
PloS one 9 (2), e87914, 2014
222014
Inhibition of MRN activity by a telomere protein motif
F Khayat, E Cannavo, M Alshmery, WR Foster, C Chahwan, M Maddalena, ...
Nature Communications 12 (1), 3856, 2021
212021
Viral decay kinetics in the highly active antiretroviral therapy-treated rhesus macaque model of AIDS
JD Deere, J Higgins, E Cannavo, A Villalobos, L Adamson, E Fromentin, ...
PLoS One 5 (7), e11640, 2010
182010
Sae2 and Rif2 regulate MRX endonuclease activity at DNA double-strand breaks in opposite manners
A Marsella, E Gobbini, C Cassani, R Tisi, E Cannavo, G Reginato, ...
Cell reports 34 (13), 2021
172021
Phenotypic analysis of hMSH2 mutations in mouse cells carrying human chromosomes
G Marra, S D’Atri, H Yan, C Perrera, E Cannavo’, B Vogelstein, J Jiricny
Cancer Research 61 (21), 7719-7721, 2001
172001
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