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Eva Szegezdi
Eva Szegezdi
Associate Professor in Biochemistry, University of Galway
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Guidelines for the use and interpretation of assays for monitoring autophagy
DJ Klionsky, K Abdelmohsen, A Abe, MJ Abedin, H Abeliovich, ...
Autophagy 12 (1), 1-222, 2016
13151*2016
Mediators of endoplasmic reticulum stress‐induced apoptosis
E Szegezdi, SE Logue, AM Gorman, A Samali
EMBO reports 7 (9), 880-885, 2006
27722006
Caspase‐12 and ER‐stress‐mediated apoptosis: the story so far
EVA Szegezdi, UNA Fitzgerald, A Samali
Annals of the new York Academy of Sciences 1010 (1), 186-194, 2003
6582003
TRAIL receptor signalling and modulation: Are we on the right TRAIL?
D Mahalingam, E Szegezdi, M Keane, S de Jong, A Samali
Cancer treatment reviews 35 (3), 280-288, 2009
3592009
Transglutaminase 2-/-mice reveal a phagocytosis-associated crosstalk between macrophages and apoptotic cells
Z Szondy, Z Sarang, P Molnár, T Németh, M Piacentini, ...
Proceedings of the National Academy of Sciences 100 (13), 7812-7817, 2003
3252003
Bcl-2 family on guard at the ER
E Szegezdi, DC MacDonald, T Ní Chonghaile, S Gupta, A Samali
American Journal of Physiology-Cell Physiology 296 (5), C941-C953, 2009
3202009
The mitochondrial death pathway: a promising therapeutic target in diseases
S Gupta, GEN Kass, E Szegezdi, B Joseph
Journal of cellular and molecular medicine 13 (6), 1004-1033, 2009
2802009
ER stress contributes to ischemia-induced cardiomyocyte apoptosis
E Szegezdi, A Duffy, ME O’Mahoney, SE Logue, LA Mylotte, T O’Brien, ...
Biochemical and biophysical research communications 349 (4), 1406-1411, 2006
2622006
Metabolic flexibility permits mesenchymal stem cell survival in an ischemic environment
LA Mylotte, AM Duffy, M Murphy, T O'Brien, A Samali, F Barry, E Szegezdi
Stem cells 26 (5), 1325-1336, 2008
2332008
Designed tumor necrosis factor-related apoptosis-inducing ligand variants initiating apoptosis exclusively via the DR5 receptor
AM van der Sloot, V Tur, E Szegezdi, MM Mullally, RH Cool, A Samali, ...
Proceedings of the National Academy of Sciences 103 (23), 8634-8639, 2006
2142006
An Unfractionated Fucoidan from Ascophyllum nodosum: Extraction, Characterization, and Apoptotic Effects in Vitro
SA Foley, E Szegezdi, B Mulloy, A Samali, MG Tuohy
Journal of natural products 74 (9), 1851-1861, 2011
1742011
Structural determinants of DISC function: new insights into death receptor-mediated apoptosis signalling
T Sessler, S Healy, A Samali, E Szegezdi
Pharmacology & therapeutics 140 (2), 186-199, 2013
1392013
Hsp27 inhibits 6-hydroxydopamine-induced cytochrome c release and apoptosis in PC12 cells
AM Gorman, E Szegezdi, DJ Quigney, A Samali
Biochemical and biophysical research communications 327 (3), 801-810, 2005
1272005
Distinct mechanisms of cardiomyocyte apoptosis induced by doxorubicin and hypoxia converge on mitochondria and are inhibited by Bcl‐xL
JLV Reeve, E Szegezdi, SE Logue, TN Chonghaile, T O’Brien, T Ritter, ...
Journal of cellular and molecular medicine 11 (3), 509-520, 2007
1072007
Rapid and efficient cancer cell killing mediated by high-affinity death receptor homotrimerizing TRAIL variants
CR Reis, AM Van Der Sloot, A Natoni, E Szegezdi, R Setroikromo, ...
Cell death & disease 1 (10), e83-e83, 2010
982010
Mechanisms of ER stress-mediated mitochondrial membrane permeabilization
S Gupta, L Cuffe, E Szegezdi, SE Logue, C Neary, S Healy, A Samali
International journal of cell biology 2010, 2010
962010
N-glycosylation of mouse TRAIL-R and human TRAIL-R1 enhances TRAIL-induced death
F Dufour, T Rattier, S Shirley, G Picarda, AA Constantinescu, A Morlé, ...
Cell Death & Differentiation 24 (3), 500-510, 2017
932017
Resistance to TRAIL in non-transformed cells is due to multiple redundant pathways
ES Marianne van Dijk, Anna Halpin-McCormick, Tamas
Cell Death and Disease 4, 2013
892013
DR4-selective tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) variants obtained by structure-based design
V Tur, AM van der Sloot, CR Reis, E Szegezdi, RH Cool, A Samali, ...
Journal of biological chemistry 283 (29), 20560-20568, 2008
832008
CD38 knockout natural killer cells expressing an affinity optimized CD38 chimeric antigen receptor successfully target acute myeloid leukemia with reduced effector cell fratricide
M Gurney, A Stikvoort, E Nolan, L Kirkham-McCarthy, S Khoruzhenko, ...
Haematologica 107 (2), 437, 2022
782022
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