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David M. Shechner
David M. Shechner
Assistant Professor of Pharmacology, University of Washington
Adresse e-mail validée de uw.edu - Page d'accueil
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Multiplexable, locus-specific targeting of long RNAs with CRISPR-Display
DM Shechner, E Hacisuleyman, ST Younger, JL Rinn
Nature methods 12 (7), 664-670, 2015
3182015
Chromatin environment, transcriptional regulation, and splicing distinguish lincRNAs and mRNAs
M Melé, K Mattioli, W Mallard, DM Shechner, C Gerhardinger, JL Rinn
Genome research 27 (1), 27-37, 2017
2432017
Live-cell mapping of organelle-associated RNAs via proximity biotinylation combined with protein-RNA crosslinking
P Kaewsapsak, DM Shechner, W Mallard, JL Rinn, AY Ting
Elife 6, e29224, 2017
1632017
Crystal structure of the catalytic core of an RNA-polymerase ribozyme
DM Shechner, RA Grant, SC Bagby, Y Koldobskaya, JA Piccirilli, ...
Science 326 (5957), 1271-1275, 2009
1402009
Directed evolution of split APEX2 peroxidase
Y Han, TC Branon, JD Martell, D Boassa, D Shechner, MH Ellisman, ...
ACS Chemical Biology 14 (4), 619-635, 2019
1382019
High‐throughput identification of RNA nuclear enrichment sequences
CJ Shukla, AL McCorkindale, C Gerhardinger, KD Korthauer, MN Cabili, ...
The EMBO journal 37 (6), e98452, 2018
1092018
Spatiotemporal allele organization by allele-specific CRISPR live-cell imaging (SNP-CLING)
PG Maass, AR Barutcu, DM Shechner, CL Weiner, M Melé, JL Rinn
Nature structural & molecular biology 25 (2), 176-184, 2018
902018
A portable RNA sequence whose recognition by a synthetic antibody facilitates structural determination
Y Koldobskaya, EM Duguid, DM Shechner, NB Suslov, J Ye, SS Sidhu, ...
Nature structural & molecular biology 18 (1), 100-106, 2011
822011
The structural basis of RNA-catalyzed RNA polymerization
DM Shechner, DP Bartel
Nature structural & molecular biology 18 (9), 1036-1042, 2011
532011
A class I ligase ribozyme with reduced Mg2+ dependence: Selection, sequence analysis, and identification of functional tertiary interactions
SC Bagby, NH Bergman, DM Shechner, C Yen, DP Bartel
Rna 15 (12), 2129-2146, 2009
242009
CRISPR Display: A modular method for locus-specific targeting of long noncoding RNAs and synthetic RNA devices in vivo
DM Shechner, E Hacisüleyman, ST Younger, JL Rinn
Nature methods 12 (7), 664, 2015
102015
‘Morphs’(MRFs): metal-reversible folding domains for differential IgG binding
SF Marino, D Shechner, L Regan
Chemistry & biology 8 (12), 1221-1229, 2001
92001
Oligonucleotide-directed proximity-interactome mapping (O-MAP): A unified method for discovering RNA-interacting proteins, transcripts and genomic loci in situ
AF Tsue, EE Kania, DQ Lei, R Fields, CD McGann, E Hershberg, X Deng, ...
bioRxiv, 2023.01. 19.524825, 2023
42023
Methods of making and using guide RNA for use with Cas9 systems
JL Rinn, DM Shechner
US Patent 10,920,221, 2021
42021
Targeting Noncoding RNA Domains to Genomic Loci with CRISPR-Display: Guidelines for Designing, Building, and Testing sgRNA–ncRNA Expression Constructs
DM Shechner
CRISPR Guide RNA Design: Methods and Protocols, 115-152, 2021
12021
Architecture of an RNA polymerase ribozyme illuminates the RNA World
DM Shechner
Trends in Genetics, 2024
2024
High-Throughput Identification of Calcium Regulated Proteins Across Diverse Proteomes
TM Locke, R Fields, H Gizinski, GM Otto, DM Shechner, MD Berg, J Villen, ...
bioRxiv, 2024.01. 18.575273, 2024
2024
Programmable peroxidase-assisted signal amplification enables flexible detection of nucleic acid targets in cellular and histopathological specimens
S Attar, VE Browning, Y Liu, EK Nichols, AF Tsue, DM Shechner, ...
bioRxiv, 2023.01. 30.526264, 2023
2023
Efficient and highly amplified imaging of nucleic acid targets in cellular and histopathological samples with pSABER
S Attar, VE Browning, Y Liu, EK Nichols, AF Tsue, DM Shechner, ...
bioRxiv, 2023.01. 30.526264, 2023
2023
Oligonucleotide-directed proximity-interactome mapping (O-MAP): A unified method for discovering RNA-interactions and probing RNA-scaffolded compartments within intact cells
D Shechner, A Tsue, E Kania, R Fields, X Deng, SE Ong, C Disteche, ...
Journal of Biological Chemistry 299 (3), S678, 2023
2023
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