| TNFα blockade overcomes resistance to anti-PD-1 in experimental melanoma F Bertrand, A Montfort, E Marcheteau, C Imbert, J Gilhodes, T Filleron, ... Nature communications 8 (1), 2256, 2017 | 334 | 2017 |
| The TNF paradox in cancer progression and immunotherapy A Montfort, C Colacios, T Levade, N Andrieu-Abadie, N Meyer, B Ségui Frontiers in immunology 10, 457367, 2019 | 273 | 2019 |
| Sphingolipids as modulators of cancer cell death: potential therapeutic targets B Ségui, N Andrieu-Abadie, JP Jaffrézou, H Benoist, T Levade Biochimica et Biophysica Acta (BBA)-Biomembranes 1758 (12), 2104-2120, 2006 | 155 | 2006 |
| Caspase-10 triggers Bid cleavage and caspase cascade activation in FasL-induced apoptosis D Milhas, O Cuvillier, N Therville, P Clavé, M Thomsen, T Levade, ... Journal of Biological Chemistry 280 (20), 19836-19842, 2005 | 155 | 2005 |
| The CB1 cannabinoid receptor of astrocytes is coupled to sphingomyelin hydrolysis through the adaptor protein fan C Sánchez, D Rueda, B Ségui, I Galve-Roperh, T Levade, M Guzmán Molecular pharmacology 59 (5), 955-959, 2001 | 147 | 2001 |
| Involvement of FAN in TNF-induced apoptosis B Ségui, O Cuvillier, S Adam-Klages, V Garcia, S Malagarie-Cazenave, ... The Journal of clinical investigation 108 (1), 143-151, 2001 | 143 | 2001 |
| OPA1 cleavage depends on decreased mitochondrial ATP level and bivalent metals L Baricault, B Ségui, L Guégand, A Olichon, A Valette, F Larminat, ... Experimental cell research 313 (17), 3800-3808, 2007 | 131 | 2007 |
| Cleavage and cytoplasmic relocalization of histone deacetylase 3 are important for apoptosis progression F Escaffit, O Vaute, M Chevillard-Briet, B Segui, Y Takami, T Nakayama, ... Molecular and cellular biology 27 (2), 554-567, 2007 | 109 | 2007 |
| Blocking Tumor Necrosis Factor α Enhances CD8 T-cell–dependent immunity in experimental melanoma F Bertrand, J Rochotte, C Colacios, A Montfort, AF Tilkin-Mariamé, ... Cancer research 75 (13), 2619-2628, 2015 | 107 | 2015 |
| Resistance of melanoma to immune checkpoint inhibitors is overcome by targeting the sphingosine kinase-1 C Imbert, A Montfort, M Fraisse, E Marcheteau, J Gilhodes, E Martin, ... Nature communications 11 (1), 437, 2020 | 105 | 2020 |
| Current thoughts on the phosphatidylinositol transfer protein family V Allen-Baume, B Ségui, S Cockcroft FEBS letters 531 (1), 74-80, 2002 | 101 | 2002 |
| IL-6 deficiency attenuates murine diet-induced non-alcoholic steatohepatitis E Mas, M Danjoux, V Garcia, S Carpentier, B Ségui, T Levade PloS one 4 (11), e7929, 2009 | 99 | 2009 |
| Downregulation of ceramide synthase-6 during epithelial-to-mesenchymal transition reduces plasma membrane fluidity and cancer cell motility V Edmond, F Dufour, G Poiroux, K Shoji, M Malleter, A Fouqué, S Tauzin, ... Oncogene 34 (8), 996-1005, 2015 | 89 | 2015 |
| CD40 signals apoptosis through FAN-regulated activation of the sphingomyelin-ceramide pathway B Ségui, N Andrieu-Abadie, S Adam-Klages, O Meilhac, D Kreder, ... Journal of Biological Chemistry 274 (52), 37251-37258, 1999 | 89 | 1999 |
| Ceramide in apoptosis: a revisited role T Levade, S Malagarie-Cazenave, V Gouazé, B Ségui, C Tardy, S Betito, ... Neurochemical research 27, 601-607, 2002 | 85 | 2002 |
| CD95 triggers Orai1-mediated localized Ca2+ entry, regulates recruitment of protein kinase C (PKC) β2, and prevents death-inducing signaling complex formation N Khadra, L Bresson-Bepoldin, A Penna, B Chaigne-Delalande, B Ségui, ... Proceedings of the National Academy of Sciences 108 (47), 19072-19077, 2011 | 72 | 2011 |
| Stress‐induced apoptosis is not mediated by endolysosomal ceramide B SéGUI, C BEZOMBES, E URO‐COSTE, JA MEDIN, ... The FASEB Journal 14 (1), 36-47, 2000 | 71 | 2000 |
| Dual role of sphingosine kinase-1 in promoting the differentiation of dermal fibroblasts and the dissemination of melanoma cells V Albinet, ML Bats, A Huwiler, P Rochaix, C Chevreau, B Segui, T Levade, ... Oncogene 33 (26), 3364-3373, 2014 | 69 | 2014 |
| Combining nivolumab and ipilimumab with infliximab or certolizumab in patients with advanced melanoma: first results of a phase Ib clinical trial A Montfort, T Filleron, M Virazels, C Dufau, J Milhès, C Pagès, P Olivier, ... Clinical Cancer Research 27 (4), 1037-1047, 2021 | 68 | 2021 |
| Caspase-mediated inhibition of sphingomyelin synthesis is involved in FasL-triggered cell death E Lafont, D Milhas, S Carpentier, V Garcia, ZX Jin, H Umehara, T Okazaki, ... Cell Death & Differentiation 17 (4), 642-654, 2010 | 68 | 2010 |
Nicolas MEYERMD, PhD, Dermatologist, Professor, CHU de Toulouse, FranceAdresse e-mail validée de chu-toulouse.fr
