| Oncogenes and signal transduction LC Cantley, KR Auger, C Carpenter, B Duckworth, A Graziani, R Kapeller, ... Cell 64 (2), 281-302, 1991 | 3551 | 1991 |
| Inhibition of BET recruitment to chromatin as an effective treatment for MLL-fusion leukaemia MA Dawson, RK Prinjha, A Dittmann, G Giotopoulos, M Bantscheff, ... Nature 478 (7370), 529-533, 2011 | 1691 | 2011 |
| PDGF-dependent tyrosine phosphorylation stimulates production of novel polyphosphoinositides in intact cells KR Auger, LA Serunian, SP Soltoff, P Libby, LC Cantley Cell 57 (1), 167-175, 1989 | 1158 | 1989 |
| Purification and characterization of phosphoinositide 3-kinase from rat liver. CL Carpenter, BC Duckworth, KR Auger, B Cohen, BS Schaffhausen, ... Journal of Biological Chemistry 265 (32), 19704-19711, 1990 | 827 | 1990 |
| Endotoxin and tumor necrosis factor induce interleukin-1 gene expression in adult human vascular endothelial cells. P Libby, JM Ordovas, KR Auger, AH Robbins, LK Birinyi, CA Dinarello The American journal of pathology 124 (2), 179, 1986 | 643 | 1986 |
| Transformation of chicken cells by the gene encoding the catalytic subunit of PI 3-kinase HW Chang, M Aoki, D Fruman, KR Auger, A Bellacosa, PN Tsichlis, ... Science 276 (5320), 1848-1850, 1997 | 536 | 1997 |
| Phosphoinositide 3-kinase is activated by phosphopeptides that bind to the SH2 domains of the 85-kDa subunit CL Carpenter, KR Auger, M Chanudhuri, M Yoakim, B Schaffhausen, ... Journal of biological chemistry 268 (13), 9478-9483, 1993 | 474 | 1993 |
| Discovery of GSK2126458, a highly potent inhibitor of PI3K and the mammalian target of rapamycin SD Knight, ND Adams, JL Burgess, AM Chaudhari, MG Darcy, ... ACS Medicinal Chemistry Letters 1 (1), 39-43, 2010 | 404 | 2010 |
| Interleukin 1 induces interleukin 1. II. Recombinant human interleukin 1 induces interleukin 1 production by adult human vascular endothelial cells. SJ Warner, KR Auger, P Libby Journal of immunology (Baltimore, Md.: 1950) 139 (6), 1911-1917, 1987 | 338 | 1987 |
| Inducible interleukin-1 gene expression in human vascular smooth muscle cells. P Libby, JM Ordovas, LK Birinyi, KR Auger, CA Dinarello The Journal of clinical investigation 78 (6), 1432-1438, 1986 | 321 | 1986 |
| A tightly associated serine/threonine protein kinase regulates phosphoinositide 3-kinase activity CL Carpenter, KR Auger, BC Duckworth, WM Hou, B Schaffhausen, ... Molecular and cellular biology 13 (3), 1657-1665, 1993 | 295 | 1993 |
| Human interleukin 1 induces interleukin 1 gene expression in human vascular smooth muscle cells. SJ Warner, KR Auger, P Libby The Journal of experimental medicine 165 (5), 1316-1331, 1987 | 290 | 1987 |
| Human mdm2 mediates multiple mono-ubiquitination of p53 by a mechanism requiring enzyme isomerization Z Lai, KV Ferry, MA Diamond, KE Wee, YB Kim, J Ma, T Yang, PA Benfield, ... Journal of Biological Chemistry 276 (33), 31357-31367, 2001 | 239 | 2001 |
| BET inhibition silences expression of MYCN and BCL2 and induces cytotoxicity in neuroblastoma tumor models A Wyce, G Ganji, KN Smitheman, C Chung, S Korenchuk, Y Bai, ... PloS one 8 (8), e72967, 2013 | 224 | 2013 |
| Polyoma middle tumor antigen interacts with SHC protein via the NPTY (Asn-Pro-Thr-Tyr) motif in middle tumor antigen. KS Campbell, E Ogris, B Burke, W Su, KR Auger, BJ Druker, ... Proceedings of the National Academy of Sciences 91 (14), 6344-6348, 1994 | 207 | 1994 |
| Inhibition of SH2 domain/phosphoprotein association by a nonhydrolyzable phosphonopeptide SM Domchek, KR Auger, S Chatterjee, TR Burke Jr, SE Shoelson Biochemistry 31 (41), 9865-9870, 1992 | 179 | 1992 |
| Identification and quantification of polyphosphoinositides produced in response to platelet-derived growth factor stimulation LA Serunian, KR Auger, LC Cantley Methods in Enzymology;(United States) 198, 1991 | 167 | 1991 |
| Phosphatidylinositol 3-kinase and its novel product, phosphatidylinositol 3-phosphate, are present in Saccharomyces cerevisiae KR Auger, CL Carpenter, LC Cantley, L Varticovski Journal of Biological Chemistry 264 (34), 20181-20184, 1989 | 167 | 1989 |
| Effects of oncogenic p110α subunit mutations on the lipid kinase activity of phosphoinositide 3-kinase JD Carson, G Van Aller, R Lehr, RH Sinnamon, RB Kirkpatrick, KR Auger, ... Biochemical Journal 409 (2), 519-524, 2008 | 156 | 2008 |
| Molecular target class is predictive of in vitro response profile J Greshock, KE Bachman, YY Degenhardt, J Jing, YH Wen, S Eastman, ... Cancer research 70 (9), 3677-3686, 2010 | 149 | 2010 |
Lewis CantleyDana Farber Cancer Center and Harvard Medical SchoolAdresse e-mail validée de med.cornell.edu
