Suivre
David Gray
David Gray
Head of Biology, Drug Discovery Unit, University of Dundee
Adresse e-mail validée de dundee.ac.uk - Page d'accueil
Titre
Citée par
Citée par
Année
A novel multiple-stage antimalarial agent that inhibits protein synthesis
B Baragaña, I Hallyburton, MCS Lee, NR Norcross, R Grimaldi, TD Otto, ...
Nature 522 (7556), 315-320, 2015
4312015
Anti-trypanosomatid drug discovery: an ongoing challenge and a continuing need
MC Field, D Horn, AH Fairlamb, MAJ Ferguson, DW Gray, KD Read, ...
Nature Reviews Microbiology 15 (4), 217-231, 2017
4072017
Spatiotemporal controlled delivery of nanoparticles to injured vasculature
JM Chan, L Zhang, R Tong, D Ghosh, W Gao, G Liao, KP Yuet, D Gray, ...
Proceedings of the National Academy of Sciences 107 (5), 2213-2218, 2010
2762010
New compound sets identified from high throughput phenotypic screening against three kinetoplastid parasites: an open resource
I Pena, M Pilar Manzano, J Cantizani, A Kessler, J Alonso-Padilla, ...
Scientific reports 5 (1), 8771, 2015
2692015
Novel signal transduction pathway mediating endothelium-dependent beta-adrenoceptor vasorelaxation in rat thoracic aorta.
DW Gray, I Marshall
British journal of pharmacology 107 (3), 684, 1992
2241992
Pharmacological properties of the enhanced-affinity glucocorticoid fluticasone furoate in vitro and in an in vivo model of respiratory inflammatory disease
M Salter, K Biggadike, JL Matthews, MR West, MV Haase, SN Farrow, ...
American Journal of Physiology-Lung Cellular and Molecular Physiology 293 (3 …, 2007
1952007
Human α‐calcitonin gene‐related peptide stimulates adenylate cyclase and guanylate cyclase and relaxes rat thoracic aorta by releasing nitric oxide
DW Gray, I Marshall
British journal of pharmacology 107 (3), 691-696, 1992
1781992
Comparison of a high-throughput high-content intracellular Leishmania donovani assay with an axenic amastigote assay
M De Rycker, I Hallyburton, J Thomas, L Campbell, S Wyllie, D Joshi, ...
Antimicrobial agents and chemotherapy 57 (7), 2913-2922, 2013
1702013
Preclinical candidate for the treatment of visceral leishmaniasis that acts through proteasome inhibition
S Wyllie, S Brand, M Thomas, M De Rycker, C Chung, I Pena, ...
Proceedings of the National Academy of Sciences 116 (19), 9318-9323, 2019
1252019
Cyclin-dependent kinase 12 is a drug target for visceral leishmaniasis
S Wyllie, M Thomas, S Patterson, S Crouch, M De Rycker, R Lowe, ...
Nature 560 (7717), 192-197, 2018
1242018
Nitric oxide synthesis inhibitors attenuate calcitonin gene-related peptide endothelium-dependent vasorelaxation in rat aorta
DW Gray, I Marshall
European journal of pharmacology 212 (1), 37-42, 1992
1151992
Lysyl-tRNA synthetase as a drug target in malaria and cryptosporidiosis
B Baragaña, B Forte, R Choi, S Nakazawa Hewitt, JA Bueren-Calabuig, ...
Proceedings of the National Academy of Sciences 116 (14), 7015-7020, 2019
1052019
Identification of small molecule inhibitors of pre-mRNA splicing
A Pawellek, S McElroy, T Samatov, L Mitchell, A Woodland, U Ryder, ...
Journal of Biological Chemistry 289 (50), 34683-34698, 2014
872014
Development of Trypanosoma cruzi in vitro assays to identify compounds suitable for progression in Chagas’ disease drug discovery
LM MacLean, J Thomas, MD Lewis, I Cotillo, DW Gray, M De Rycker
PLoS neglected tropical diseases 12 (7), e0006612, 2018
852018
GW627368X ((N‐{2‐[4‐(4, 9‐diethoxy‐1‐oxo‐1, 3‐dihydro‐2H‐benzo [f] isoindol‐2‐yl) phenyl] acetyl} benzene sulphonamide): a novel, potent and selective prostanoid EP4 receptor …
RJ Wilson, GMP Giblin, S Roomans, SA Rhodes, KA Cartwright, VJ Shield, ...
British journal of pharmacology 148 (3), 326-339, 2006
812006
Discovery of a quinoline-4-carboxamide derivative with a novel mechanism of action, multistage antimalarial activity, and potent in vivo efficacy
B Baragaña, NR Norcross, C Wilson, A Porzelle, I Hallyburton, R Grimaldi, ...
Journal of medicinal chemistry 59 (21), 9672-9685, 2016
782016
Identification of Trypanocidal Activity for Known Clinical Compounds Using a New Trypanosoma cruzi Hit-Discovery Screening Cascade
M De Rycker, J Thomas, J Riley, SJ Brough, TJ Miles, DW Gray
PLoS neglected tropical diseases 10 (4), e0004584, 2016
712016
Functional pharmacology of human prostanoid EP2 and EP4 receptors
RJ Wilson, SA Rhodes, RL Wood, VJ Shield, LS Noel, DW Gray, H Giles
European journal of pharmacology 501 (1-3), 49-58, 2004
682004
Biochemical characterization of protease activity of Nsp3 from SARS-CoV-2 and its inhibition by nanobodies
LA Armstrong, SM Lange, V Dee Cesare, SP Matthews, RS Nirujogi, ...
PloS one 16 (7), e0253364, 2021
652021
Biochemical and Structural Characterization of Selective Allosteric Inhibitors of the Plasmodium falciparum Drug Target, Prolyl-tRNA-synthetase
SN Hewitt, DM Dranow, BG Horst, JA Abendroth, B Forte, I Hallyburton, ...
ACS infectious diseases 3 (1), 34-44, 2017
572017
Le système ne peut pas réaliser cette opération maintenant. Veuillez réessayer plus tard.
Articles 1–20