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Endothelium-independent vasodilator effects of the flavonoid quercetin and its methylated metabolites in rat conductance and resistance arteries
F Pérez-Vizcaı́no, M Ibarra, AL Cogolludo, J Duarte, F Zaragozá-Arnáez, ...
Journal of Pharmacology and Experimental Therapeutics 302 (1), 66-72, 2002
Serotonin Inhibits Voltage-Gated K+ Currents in Pulmonary Artery Smooth Muscle Cells: Role of 5-HT2A Receptors, Caveolin-1, and KV1.5 Channel Internalization
A Cogolludo, L Moreno, F Lodi, G Frazziano, L Cobeno, J Tamargo, ...
Circulation research 98 (7), 931-938, 2006
Thromboxane A2-Induced Inhibition of Voltage-Gated K+ Channels and Pulmonary Vasoconstriction: Role of Protein Kinase Cζ
A Cogolludo, L Moreno, L Bosca, J Tamargo, F Perez-Vizcaino
Circulation research 93 (7), 656-663, 2003
Na+ controls hypoxic signalling by the mitochondrial respiratory chain
P Hernansanz-Agustín, C Choya-Foces, S Carregal-Romero, E Ramos, ...
Nature 586 (7828), 287-291, 2020
Quercetin and isorhamnetin prevent endothelial dysfunction, superoxide production, and overexpression of p47phox induced by angiotensin II in rat aorta
M Sanchez, F Lodi, R Vera, IC Villar, A Cogolludo, R Jimenez, L Moreno, ...
The Journal of nutrition 137 (4), 910-915, 2007
The dietary flavonoid quercetin activates BKCa currents in coronary arteries via production of H2O2. Role in vasodilatation
A Cogolludo, G Frazziano, AM Briones, L Cobeño, L Moreno, F Lodi, ...
Cardiovascular research 73 (2), 424-431, 2007
Activation of neutral sphingomyelinase is involved in acute hypoxic pulmonary vasoconstriction
A Cogolludo, L Moreno, G Frazziano, J Moral-Sanz, C Menendez, ...
Cardiovascular research 82 (2), 296-302, 2009
Glucuronidated and sulfated metabolites of the flavonoid quercetin prevent endothelial dysfunction but lack direct vasorelaxant effects in rat aorta
F Lodi, R Jimenez, L Moreno, PA Kroon, PW Needs, DA Hughes, ...
Atherosclerosis 204 (1), 34-39, 2009
Nitric oxide (NO) scavenging and NO protecting effects of quercetin and their biological significance in vascular smooth muscle
G Lopez-Lopez, L Moreno, A Cogolludo, M Galisteo, M Ibarra, J Duarte, ...
Molecular pharmacology 65 (4), 851-859, 2004
The flavonoid quercetin induces apoptosis and inhibits JNK activation in intimal vascular smooth muscle cells
F Perez-Vizcaino, D Bishop-Bailley, F Lodi, J Duarte, A Cogolludo, ...
Biochemical and biophysical research communications 346 (3), 919-925, 2006
Reactive oxygen species signaling in pulmonary vascular smooth muscle
F Perez-Vizcaino, A Cogolludo, L Moreno
Respiratory physiology & neurobiology 174 (3), 212-220, 2010
HIF-2α-mediated induction of pulmonary thrombospondin-1 contributes to hypoxia-driven vascular remodelling and vasoconstriction
D Labrousse-Arias, R Castillo-Gonzalez, NM Rogers, M Torres-Capelli, ...
Cardiovascular research 109 (1), 115-130, 2016
Diabetes induces pulmonary artery endothelial dysfunction by NADPH oxidase induction
JG Lopez-Lopez, J Moral-Sanz, G Frazziano, MJ Gomez-Villalobos, ...
American journal of physiology-lung cellular and molecular physiology 295 (5 …, 2008
The flavonoid quercetin reverses pulmonary hypertension in rats
D Morales-Cano, C Menendez, E Moreno, J Moral-Sanz, B Barreira, ...
PLoS One 9 (12), e114492, 2014
Role of reactive oxygen species in Kv channel inhibition and vasoconstriction induced by TP receptor activation in rat pulmonary arteries
A Cogolludo, G Frazziano, L Cobeno, L Moreno, F Lodi, E Villamor, ...
Annals of the New York Academy of Sciences 1091 (1), 41-51, 2006
Hepatocyte-secreted extracellular vesicles modify blood metabolome and endothelial function by an arginase-dependent mechanism
F Royo, L Moreno, J Mleczko, L Palomo, E Gonzalez, D Cabrera, ...
Scientific reports 7 (1), 42798, 2017
Effects of the flavonoid quercetin and its methylated metabolite isorhamnetin in isolated arteries from spontaneously hypertensive rats
M Ibarra, L Moreno, R Vera, A Cogolludo, J Duarte, J Tamargo, ...
Planta medica 69 (11), 995-1000, 2003
Cardiovascular effects of isorhamnetin and quercetin in isolated rat and porcine vascular smooth muscle and isolated rat atria
M Ibarra, F Pérez-Vizcaíno, A Cogolludo, J Duarte, F Zaragozá-Arnáez, ...
Planta medica 68 (04), 307-310, 2002
Activation of peroxisome proliferator-activated receptor-β/-δ (PPARβ/δ) prevents endothelial dysfunction in type 1 diabetic rats
AM Quintela, R Jimenez, M Gomez-Guzman, MJ Zarzuelo, P Galindo, ...
Free Radical Biology and Medicine 53 (4), 730-741, 2012
Mechanisms controlling vascular tone in pulmonary arterial hypertension: implications for vasodilator therapy
A Cogolludo, L Moreno, E Villamor
Pharmacology 79 (2), 65-75, 2007
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