Endothelium-independent vasodilator effects of the flavonoid quercetin and its methylated metabolites in rat conductance and resistance arteries F Pérez-Vizcaı́no, M Ibarra, AL Cogolludo, J Duarte, F Zaragozá-Arnáez, ... Journal of Pharmacology and Experimental Therapeutics 302 (1), 66-72, 2002 | 286 | 2002 |
Serotonin Inhibits Voltage-Gated K+ Currents in Pulmonary Artery Smooth Muscle Cells: Role of 5-HT2A Receptors, Caveolin-1, and KV1.5 Channel Internalization A Cogolludo, L Moreno, F Lodi, G Frazziano, L Cobeno, J Tamargo, ... Circulation research 98 (7), 931-938, 2006 | 227 | 2006 |
Na+ controls hypoxic signalling by the mitochondrial respiratory chain P Hernansanz-Agustín, C Choya-Foces, S Carregal-Romero, E Ramos, ... Nature 586 (7828), 287-291, 2020 | 198 | 2020 |
Thromboxane A2-Induced Inhibition of Voltage-Gated K+ Channels and Pulmonary Vasoconstriction: Role of Protein Kinase Cζ A Cogolludo, L Moreno, L Bosca, J Tamargo, F Perez-Vizcaino Circulation research 93 (7), 656-663, 2003 | 198 | 2003 |
Quercetin and isorhamnetin prevent endothelial dysfunction, superoxide production, and overexpression of p47phox induced by angiotensin II in rat aorta M Sanchez, F Lodi, R Vera, IC Villar, A Cogolludo, R Jimenez, L Moreno, ... The Journal of nutrition 137 (4), 910-915, 2007 | 156 | 2007 |
The dietary flavonoid quercetin activates BKCa currents in coronary arteries via production of H2O2. Role in vasodilatation A Cogolludo, G Frazziano, AM Briones, L Cobeño, L Moreno, F Lodi, ... Cardiovascular research 73 (2), 424-431, 2007 | 138 | 2007 |
Glucuronidated and sulfated metabolites of the flavonoid quercetin prevent endothelial dysfunction but lack direct vasorelaxant effects in rat aorta F Lodi, R Jimenez, L Moreno, PA Kroon, PW Needs, DA Hughes, ... Atherosclerosis 204 (1), 34-39, 2009 | 134 | 2009 |
Activation of neutral sphingomyelinase is involved in acute hypoxic pulmonary vasoconstriction A Cogolludo, L Moreno, G Frazziano, J Moral-Sanz, C Menendez, ... Cardiovascular research 82 (2), 296-302, 2009 | 133 | 2009 |
Nitric oxide (NO) scavenging and NO protecting effects of quercetin and their biological significance in vascular smooth muscle G Lopez-Lopez, L Moreno, A Cogolludo, M Galisteo, M Ibarra, J Duarte, ... Molecular pharmacology 65 (4), 851-859, 2004 | 122 | 2004 |
Reactive oxygen species signaling in pulmonary vascular smooth muscle F Perez-Vizcaino, A Cogolludo, L Moreno Respiratory physiology & neurobiology 174 (3), 212-220, 2010 | 110 | 2010 |
The flavonoid quercetin induces apoptosis and inhibits JNK activation in intimal vascular smooth muscle cells F Perez-Vizcaino, D Bishop-Bailley, F Lodi, J Duarte, A Cogolludo, ... Biochemical and biophysical research communications 346 (3), 919-925, 2006 | 109 | 2006 |
HIF-2α-mediated induction of pulmonary thrombospondin-1 contributes to hypoxia-driven vascular remodelling and vasoconstriction D Labrousse-Arias, R Castillo-Gonzalez, NM Rogers, M Torres-Capelli, ... Cardiovascular research 109 (1), 115-130, 2016 | 104 | 2016 |
Diabetes induces pulmonary artery endothelial dysfunction by NADPH oxidase induction JG Lopez-Lopez, J Moral-Sanz, G Frazziano, MJ Gomez-Villalobos, ... American journal of physiology-lung cellular and molecular physiology 295 (5 …, 2008 | 94 | 2008 |
Hepatocyte-secreted extracellular vesicles modify blood metabolome and endothelial function by an arginase-dependent mechanism F Royo, L Moreno, J Mleczko, L Palomo, E Gonzalez, D Cabrera, ... Scientific reports 7 (1), 42798, 2017 | 92 | 2017 |
The flavonoid quercetin reverses pulmonary hypertension in rats D Morales-Cano, C Menendez, E Moreno, J Moral-Sanz, B Barreira, ... PLoS One 9 (12), e114492, 2014 | 90 | 2014 |
Role of reactive oxygen species in Kv channel inhibition and vasoconstriction induced by TP receptor activation in rat pulmonary arteries A Cogolludo, G Frazziano, L Cobeno, L Moreno, F Lodi, E Villamor, ... Annals of the New York Academy of Sciences 1091 (1), 41-51, 2006 | 87 | 2006 |
Effects of the flavonoid quercetin and its methylated metabolite isorhamnetin in isolated arteries from spontaneously hypertensive rats M Ibarra, L Moreno, R Vera, A Cogolludo, J Duarte, J Tamargo, ... Planta medica 69 (11), 995-1000, 2003 | 83 | 2003 |
JAK2 mediates lung fibrosis, pulmonary vascular remodelling and hypertension in idiopathic pulmonary fibrosis: an experimental study J Milara, B Ballester, A Morell, JL Ortiz, J Escrivá, E Fernández, ... Thorax 73 (6), 519-529, 2018 | 81 | 2018 |
Pulmonary arterial hypertension affects the rat gut microbiome M Callejo, G Mondejar-Parreño, B Barreira, JL Izquierdo-Garcia, ... Scientific Reports 8 (1), 9681, 2018 | 79 | 2018 |
Cardiovascular effects of isorhamnetin and quercetin in isolated rat and porcine vascular smooth muscle and isolated rat atria M Ibarra, F Pérez-Vizcaíno, A Cogolludo, J Duarte, F Zaragozá-Arnáez, ... Planta medica 68 (04), 307-310, 2002 | 79 | 2002 |