Itaconyl-CoA forms a stable biradical in methylmalonyl-CoA mutase and derails its activity and repair M Ruetz, GC Campanello, M Purchal, H Shen, L McDevitt, H Gouda, ... Science 366 (6465), 589-593, 2019 | 92 | 2019 |
Exogenous 5,6‐dimethylbenzimidazole caused production of a non‐functional tetrachloroethene reductive dehalogenase in Sulfurospirillum multivorans S Keller, M Ruetz, C Kunze, B Kräutler, G Diekert, T Schubert Environmental microbiology 16 (11), 3361-3369, 2014 | 68 | 2014 |
Access to Organometallic Arylcobaltcorrins through Radical Synthesis: 4‐Ethylphenylcobalamin, a Potential “Antivitamin B 12” M Ruetz, C Gherasim, K Gruber, S Fedosov, R Banerjee, B Kräutler WILEY‐VCH Verlag, 2013 | 63 | 2013 |
A distal ligand mutes the interaction of hydrogen sulfide with human neuroglobin M Ruetz, J Kumutima, BE Lewis, MR Filipovic, N Lehnert, TL Stemmler, ... Journal of Biological Chemistry 292 (16), 6512-6528, 2017 | 57 | 2017 |
4-Ethylphenyl-Cobalamin Impairs Tissue Uptake of Vitamin B12 and Causes Vitamin B12 Deficiency in Mice E Mutti, M Ruetz, H Birn, B Kräutler, E Nexo PloS one 8 (9), e75312, 2013 | 51 | 2013 |
Phenylethynylcobalamin: A Light‐Stable and Thermolysis‐Resistant Organometallic Vitamin B12 Derivative Prepared by Radical Synthesis M Ruetz, R Salchner, K Wurst, S Fedosov, B Kräutler Angewandte Chemie International Edition 52 (43), 11406-11409, 2013 | 48 | 2013 |
Toward the Design of Photoresponsive Conditional Antivitamins B12: A Transient Absorption Study of an Arylcobalamin and an Alkynylcobalamin NA Miller, TE Wiley, KG Spears, M Ruetz, C Kieninger, B Kräutler, ... Journal of the American Chemical Society 138 (43), 14250-14256, 2016 | 43 | 2016 |
Methylfolate trap promotes bacterial thymineless death by sulfa drugs MB Guzzo, HT Nguyen, TH Pham, M Wyszczelska-Rokiel, H Jakubowski, ... PLoS pathogens 12 (10), e1005949, 2016 | 39 | 2016 |
Pathogenic mutations differentially affect the catalytic activities of the human B12-processing chaperone CblC and increase futile redox cycling C Gherasim, M Ruetz, Z Li, S Hudolin, R Banerjee Journal of Biological Chemistry 290 (18), 11393-11402, 2015 | 34 | 2015 |
Antivitamin B12 Inhibition of the Human B12‐Processing Enzyme CblC: Crystal Structure of an Inactive Ternary Complex with Glutathione as the Cosubstrate M Ruetz, A Shanmuganathan, C Gherasim, A Karasik, R Salchner, ... Angewandte Chemie International Edition 56 (26), 7387-7392, 2017 | 30 | 2017 |
A Blue Corrinoid from Partial Degradation of Vitamin B12 in Aqueous Bicarbonate: Spectra, Structure, and Interaction with Proteins of B12 Transport SN Fedosov, M Ruetz, K Gruber, NU Fedosova, B Kräutler Biochemistry 50 (37), 8090-8101, 2011 | 26 | 2011 |
Sacrificial Cobalt–Carbon Bond Homolysis in Coenzyme B12 as a Cofactor Conservation Strategy GC Campanello, M Ruetz, GJ Dodge, H Gouda, A Gupta, UT Twahir, ... Journal of the American Chemical Society 140 (41), 13205-13208, 2018 | 25 | 2018 |
Conformational change of a tryptophan residue in BtuF facilitates binding and transport of cobinamide by the vitamin B12 transporter BtuCD-F SA Mireku, M Ruetz, T Zhou, VM Korkhov, B Kräutler, KP Locher Scientific reports 7 (1), 41575, 2017 | 24 | 2017 |
Coordination chemistry controls the thiol oxidase activity of the B12-trafficking protein CblC Z Li, A Shanmuganathan, M Ruetz, K Yamada, NA Lesniak, B Kräutler, ... Journal of Biological Chemistry 292 (23), 9733-9744, 2017 | 22 | 2017 |
The human B12 trafficking protein CblC processes nitrocobalamin R Mascarenhas, Z Li, C Gherasim, M Ruetz, R Banerjee Journal of Biological Chemistry 295 (28), 9630-9640, 2020 | 19 | 2020 |
Efficient fluorophores based on pyridyl-enolato and enamido difluoroboron complexes: Simple alternatives to boron-dipyrromethene (bodipy) dyes M Graser, H Kopacka, K Wurst, M Ruetz, CR Kreutz, T Müller, ... Inorganica Chimica Acta 405, 116-120, 2013 | 19 | 2013 |
Vitamin B12 and derivatives—In vitro permeation studies across Caco-2 cell monolayers and freshly excised rat intestinal mucosa K Netsomboon, A Feßler, L Erletz, F Prüfert, M Ruetz, C Kieninger, ... International Journal of Pharmaceutics 497 (1-2), 129-135, 2016 | 18 | 2016 |
Mobile loop dynamics in adenosyltransferase control binding and reactivity of coenzyme B12 R Mascarenhas, M Ruetz, L McDevitt, M Koutmos, R Banerjee Proceedings of the National Academy of Sciences 117 (48), 30412-30422, 2020 | 16 | 2020 |
Zugang zu metallorganischen Arylcobaltcorrinen durch radikalische Synthese: 4‐Ethylphenylcobalamin, ein potenzielles “Antivitamin B 12” M Ruetz, C Gherasim, K Gruber, S Fedosov, R Banerjee, B Kräutler WILEY‐VCH Verlag, 2013 | 16 | 2013 |
Allosteric regulation of oligomerization by a B12 trafficking G-protein is corrupted in methylmalonic aciduria M Ruetz, GC Campanello, L McDevitt, AL Yokom, PK Yadav, D Watkins, ... Cell chemical biology 26 (7), 960-969. e4, 2019 | 15 | 2019 |