Rong Chen
Rong Chen
Director of Clinical Genome Informatics & Assistant Professor, Mount Sinai School of Medicine
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ZDOCK: an initial‐stage protein‐docking algorithm
R Chen, L Li, Z Weng
Proteins: Structure, Function, and Bioinformatics 52 (1), 80-87, 2003
Personal Omics Profiling Reveals Dynamic Molecular and Medical Phenotypes
R Chen, GI Mias, J Li-Pook-Than, L Jiang, HYK Lam, R Chen, E Miriami, ...
Cell 148 (6), 1293-1307, 2012
Clinical assessment incorporating a personal genome
EA Ashley, AJ Butte, MT Wheeler, R Chen, TE Klein, FE Dewey, ...
The Lancet 375 (9725), 1525-1535, 2010
The MicroArray Quality Control (MAQC)-II study of common practices for the development and validation of microarray-based predictive models.
L Shi, G Campbell, WD Jones, F Campagne, Z Wen, SJ Walker, Z Su, ...
Nature biotechnology 28 (8), 827, 2010
A comprehensive assessment of RNA-seq accuracy, reproducibility and information content by the Sequencing Quality Control Consortium.
SMIII Consortium.
Nature Biotechnology 32 (9), 903-914, 2014
Performance comparison of exome DNA sequencing technologies
MJ Clark, R Chen, HYK Lam, KJ Karczewski, R Chen, G Euskirchen, ...
Nature Biotechnology, 2011
Docking unbound proteins using shape complementarity, desolvation, and electrostatics
R Chen, Z Weng
Proteins: Structure, Function, and Bioinformatics 47 (3), 281-294, 2002
Protein–protein docking benchmark 2.0: an update
J Mintseris, K Wiehe, B Pierce, R Anderson, R Chen, J Janin, Z Weng
Proteins: Structure, Function, and Bioinformatics 60 (2), 214-216, 2005
A novel shape complementarity scoring function for protein‐protein docking
R Chen, Z Weng
Proteins: Structure, Function, and Bioinformatics 51 (3), 397-408, 2003
A protein–protein docking benchmark
R Chen, J Mintseris, J Janin, Z Weng
Proteins: Structure, Function, and Bioinformatics 52 (1), 88-91, 2003
Network-based elucidation of human disease similarities reveals common functional modules enriched for pluripotent drug targets
S Suthram, JT Dudley, AP Chiang, R Chen, TJ Hastie, AJ Butte
PLoS computational biology 6 (2), e1000662, 2010
RDOCK: refinement of rigid‐body protein docking predictions
L Li, R Chen, Z Weng
Proteins: Structure, Function, and Bioinformatics 53 (3), 693-707, 2003
Identification of type 2 diabetes subgroups through topological analysis of patient similarity
L Li, WY Cheng, BS Glicksberg, O Gottesman, R Tamler, R Chen, ...
Science translational medicine 7 (311), 311ra174-311ra174, 2015
Performance comparison of whole-genome sequencing platforms
HYK Lam, MJ Clark, R Chen, R Chen, G Natsoulis, M O'Huallachain, ...
Nature Biotechnology, 2011
Integrating statistical pair potentials into protein complex prediction
J Mintseris, B Pierce, K Wiehe, R Anderson, R Chen, Z Weng
Proteins: Structure, Function, and Bioinformatics 69 (3), 511-520, 2007
Personalized medicine.
KK Jain
Current opinion in molecular therapeutics 4 (6), 548, 2002
Analysis of 589,306 genomes identifies individuals resilient to severe Mendelian childhood diseases
R Chen, L Shi, J Hakenberg, B Naughton, P Sklar, J Zhang, H Zhou, ...
Nature biotechnology 34 (5), 531-538, 2016
Non-synonymous and synonymous coding SNPs show similar likelihood and effect size of human disease association
R Chen, EV Davydov, M Sirota, AJ Butte
PloS one 5 (10), e13574, 2010
Ontology-driven indexing of public datasets for translational bioinformatics
N Shah, C Jonquet, A Chiang, A Butte, R Chen, M Musen
BMC bioinformatics 10 (Suppl 2), S1, 2009
Phased Whole-Genome Genetic Risk in a Family Quartet Using a Major Allele Reference Sequence
FE Dewey, R Chen, SP Cordero, KE Ormond, C Caleshu, KJ Karczewski, ...
PLoS Genet 7 (9), e1002280, 2011
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