Robert I Lehrer
Robert I Lehrer
Professor of Medicine, Emeritus, UCLA
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Defensins. Natural peptide antibiotics of human neutrophils.
T Ganz, ME Selsted, D Szklarek, SS Harwig, K Daher, DF Bainton, ...
The Journal of clinical investigation 76 (4), 1427-1435, 1985
Cationic peptides: a new source of antibiotics
REW Hancock, R Lehrer
Trends in biotechnology 16 (2), 82-88, 1998
Defensins: antimicrobial and cytotoxic peptides of mammalian cells
RI Lehrer, AK Lichtenstein, T Ganz
Annual review of immunology 11 (1), 105-128, 1993
Antimicrobial peptides in mammalian and insect host defence
RI Lehrer, T Ganz
Current opinion in immunology 11 (1), 23-27, 1999
Activities of LL-37, a cathelin-associated antimicrobial peptide of human neutrophils
J Turner, Y Cho, NN Dinh, AJ Waring, RI Lehrer
Antimicrobial agents and chemotherapy 42 (9), 2206-2214, 1998
Interaction of human defensins with Escherichia coli. Mechanism of bactericidal activity.
RI Lehrer, A Barton, KA Daher, SS Harwig, T Ganz, ME Selsted
The Journal of clinical investigation 84 (2), 553-561, 1989
Defensins of vertebrate animals
RI Lehrer, T Ganz
Current opinion in immunology 14 (1), 96-102, 2002
Ultrasensitive assays for endogenous antimicrobial polypeptides
RI Lehrer, M Rosenman, SSSL Harwig, R Jackson, P Eisenhauer
Journal of immunological methods 137 (2), 167-173, 1991
Leukocyte myeloperoxidase deficiency and disseminated candidiasis: the role of myeloperoxidase in resistance to Candida infection
RI Lehrer, MJ Cline
The Journal of clinical investigation 48 (8), 1478-1488, 1969
Widespread expression of beta‐defensin hBD‐1 in human secretory glands and epithelial cells
C Zhao, I Wang, RI Lehrer
FEBS letters 396 (2-3), 319-322, 1996
Antimicrobial defensin peptides form voltage-dependent ion-permeable channels in planar lipid bilayer membranes.
BL Kagan, ME Selsted, T Ganz, RI Lehrer
Proceedings of the National Academy of Sciences 87 (1), 210-214, 1990
Plectasin is a peptide antibiotic with therapeutic potential from a saprophytic fungus
PH Mygind, RL Fischer, KM Schnorr, MT Hansen, CP Sönksen, ...
Nature 437 (7061), 975-980, 2005
Primate defensins
RI Lehrer
Nature Reviews Microbiology 2 (9), 727-738, 2004
Direct inactivation of viruses by human granulocyte defensins
KA Daher, ME Selsted, RI Lehrer
Journal of virology 60 (3), 1068-1074, 1986
Primary structures of three human neutrophil defensins.
ME Selsted, SS Harwig, T Ganz, JW Schilling, RI Lehrer
The Journal of clinical investigation 76 (4), 1436-1439, 1985
Interaction of Candida albicans with Human Leukocytes and Serum
RI Lehrer, MJ Cline
Journal of bacteriology 98 (3), 996-1004, 1969
Protegrins: leukocyte antimicrobial peptides that combine features of corticostatic defensins and tachyplesins
VN Kokryakov, SSL Harwig, EA Panyutich, AA Shevchenko, GM Aleshina, ...
FEBS letters 327 (2), 231-236, 1993
Monocyte-chemotactic activity of defensins from human neutrophils.
MC Territo, T Ganz, ME Selsted, RL Lehrer
The Journal of clinical investigation 84 (6), 2017-2020, 1989
Antimicrobial peptides of vertebrates
T Ganz, RI Lehrer
Current opinion in immunology 10 (1), 41-44, 1998
Crystallization of antimicrobial pores in membranes: magainin and protegrin
L Yang, TM Weiss, RI Lehrer, HW Huang
Biophysical journal 79 (4), 2002-2009, 2000
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