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laurent devel
laurent devel
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Matrix metalloproteinases: from molecular mechanisms to physiology, pathophysiology, and pharmacology
LGN de Almeida, H Thode, Y Eslambolchi, S Chopra, D Young, S Gill, ...
Pharmacological Reviews 74 (3), 714-770, 2022
3462022
A new transcriptional role for matrix metalloproteinase-12 in antiviral immunity
DJ Marchant, CL Bellac, TJ Moraes, SJ Wadsworth, A Dufour, GS Butler, ...
Nature medicine 20 (5), 493-502, 2014
2802014
A selective matrix metalloproteinase-12 inhibitor retards atherosclerotic plaque development in apolipoprotein E–knockout mice
JL Johnson, L Devel, B Czarny, SJ George, CL Jackson, V Rogakos, ...
Arteriosclerosis, thrombosis, and vascular biology 31 (3), 528-535, 2011
1972011
Development of selective inhibitors and substrate of matrix metalloproteinase-12
L Devel, V Rogakos, A David, A Makaritis, F Beau, P Cuniasse, A Yiotakis, ...
Journal of Biological Chemistry 281 (16), 11152-11160, 2006
1772006
Future challenges facing the development of specific active-site-directed synthetic inhibitors of MMPs
P Cuniasse, L Devel, A Makaritis, F Beau, D Georgiadis, M Matziari, ...
Biochimie 87 (3-4), 393-402, 2005
1302005
Third generation of matrix metalloprotease inhibitors: Gain in selectivity by targeting the depth of the S1′ cavity
L Devel, B Czarny, F Beau, D Georgiadis, E Stura, V Dive
Biochimie 92 (11), 1501-1508, 2010
1022010
Crystallization of bi-functional ligand protein complexes
C Antoni, L Vera, L Devel, MP Catalani, B Czarny, E Cassar-Lajeunesse, ...
Journal of Structural Biology 182 (3), 246-254, 2013
682013
Matrix metalloproteinase inhibition protects rat livers from prolonged cold ischemia–warm reperfusion injury
V Defamie, M Laurens, D Patrono, L Devel, A Brault, MC Saint‐Paul, ...
Hepatology 47 (1), 177-185, 2008
622008
Cross‐linking yield variation of a potent matrix metalloproteinase photoaffinity probe and consequences for functional proteomics
A David, D Steer, S Bregant, L Devel, A Makaritis, F Beau, A Yiotakis, ...
Angewandte Chemie International Edition 46 (18), 3275-3277, 2007
552007
Insights from selective non-phosphinic inhibitors of MMP-12 tailored to fit with an S1′ loop canonical conformation
L Devel, S Garcia, B Czarny, F Beau, E Lajeunesse, L Vera, D Georgiadis, ...
Journal of Biological Chemistry 285 (46), 35900-35909, 2010
522010
Synthesis and Biodistribution Studies of 3H- and 64Cu-Labeled Dendritic Polyglycerol and Dendritic Polyglycerol Sulfate
K Pant, D Gröger, R Bergmann, J Pietzsch, J Steinbach, B Graham, ...
Bioconjugate Chemistry 26 (5), 906-918, 2015
422015
Molecular determinants of a selective matrix metalloprotease-12 inhibitor: insights from crystallography and thermodynamic studies
B Czarny, EA Stura, L Devel, L Vera, E Cassar-Lajeunesse, F Beau, ...
Journal of medicinal chemistry 56 (3), 1149-1159, 2013
402013
Molecular determinants of matrix metalloproteinase-12 covalent modification by a photoaffinity probe: insights into activity-based probe development and conformational …
AS Dabert-Gay, B Czarny, L Devel, F Beau, E Lajeunesse, S Bregant, ...
Journal of Biological Chemistry 283 (45), 31058-31067, 2008
402008
In vivo imaging of matrix metalloproteinase 12 and matrix metalloproteinase 13 activities in the mouse model of collagen‐induced arthritis
NH Lim, E Meinjohanns, G Bou‐Gharios, LL Gompels, E Nuti, A Rossello, ...
Arthritis & rheumatology 66 (3), 589-598, 2014
392014
Simple pseudo-dipeptides with a P2′ glutamate: a novel inhibitor family of matrix metalloproteases and other metzincins
L Devel, F Beau, M Amoura, L Vera, E Cassar-Lajeunesse, S Garcia, ...
Journal of Biological Chemistry 287 (32), 26647-26656, 2012
382012
Zinc–metalloproteinase inhibitors: Evaluation of the complex role played by the zinc-binding group on potency and selectivity
C Rouanet-Mehouas, B Czarny, F Beau, E Cassar-Lajeunesse, EA Stura, ...
Journal of medicinal chemistry 60 (1), 403-414, 2017
372017
Synthesis and in vitro and in vivo evaluation of MMP-12 selective optical probes
T Bordenave, M Helle, F Beau, D Georgiadis, L Tepshi, M Bernes, Y Ye, ...
Bioconjugate chemistry 27 (10), 2407-2417, 2016
372016
Detection of matrix metalloproteinase active forms in complex proteomes: evaluation of affinity versus photoaffinity capture
S Bregant, C Huillet, L Devel, AS Dabert-Gay, F Beau, R Thai, B Czarny, ...
Journal of proteome research 8 (5), 2484-2494, 2009
312009
Optical imaging of MMP-12 active form in inflammation and aneurysm
M Razavian, T Bordenave, D Georgiadis, F Beau, J Zhang, R Golestani, ...
Scientific reports 6 (1), 38345, 2016
282016
Probing the mechanism of allylic substitution of Morita–Baylis–Hillman acetates (MBHAs) by using the silyl phosphonite paradigm: scope and applications of a versatile …
M Kalyva, AL Zografos, E Kapourani, E Giambazolias, L Devel, ...
Chemistry–A European Journal 21 (8), 3278-3289, 2015
272015
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