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Daniel Siegwart
Daniel Siegwart
Adresse e-mail validée de utsouthwestern.edu - Page d'accueil
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The development of microgels/nanogels for drug delivery applications
JK Oh, R Drumright, DJ Siegwart, K Matyjaszewski
Progress in polymer science 33 (4), 448-477, 2008
18402008
Selective organ targeting (SORT) nanoparticles for tissue-specific mRNA delivery and CRISPR–Cas gene editing
Q Cheng, T Wei, L Farbiak, LT Johnson, SA Dilliard, DJ Siegwart
Nature nanotechnology 15 (4), 313-320, 2020
10412020
ATRP in the design of functional materials for biomedical applications
DJ Siegwart, JK Oh, K Matyjaszewski
Progress in polymer science 37 (1), 18-37, 2012
6762012
Non‐viral CRISPR/Cas gene editing in vitro and in vivo enabled by synthetic nanoparticle co‐delivery of Cas9 mRNA and sgRNA
JB Miller, S Zhang, P Kos, H Xiong, K Zhou, SS Perelman, H Zhu, ...
Angewandte Chemie 129 (4), 1079-1083, 2017
5312017
Biodegradable nanogels prepared by atom transfer radical polymerization as potential drug delivery carriers: synthesis, biodegradation, in vitro release, and bioconjugation
JK Oh, DJ Siegwart, H Lee, G Sherwood, L Peteanu, JO Hollinger, ...
Journal of the American Chemical Society 129 (18), 5939-5945, 2007
5142007
Lipopeptide nanoparticles for potent and selective siRNA delivery in rodents and nonhuman primates
Y Dong, KT Love, JR Dorkin, S Sirirungruang, Y Zhang, D Chen, ...
Proceedings of the National Academy of Sciences 111 (11), 3955-3960, 2014
4992014
Systemic nanoparticle delivery of CRISPR-Cas9 ribonucleoproteins for effective tissue specific genome editing
T Wei, Q Cheng, YL Min, EN Olson, DJ Siegwart
Nature communications 11 (1), 1-12, 2020
4002020
Strategies, design, and chemistry in siRNA delivery systems
Y Dong, DJ Siegwart, DG Anderson
Advanced drug delivery reviews 144, 133-147, 2019
3932019
Gpr132 sensing of lactate mediates tumor–macrophage interplay to promote breast cancer metastasis
P Chen, H Zuo, H Xiong, MJ Kolar, Q Chu, A Saghatelian, DJ Siegwart, ...
Proceedings of the National Academy of Sciences 114 (3), 580-585, 2017
3332017
On the mechanism of tissue-specific mRNA delivery by selective organ targeting nanoparticles
SA Dilliard, Q Cheng, DJ Siegwart
Proceedings of the national academy of sciences 118 (52), e2109256118, 2021
3152021
Membrane-destabilizing ionizable phospholipids for organ-selective mRNA delivery and CRISPR–Cas gene editing
S Liu, Q Cheng, T Wei, X Yu, LT Johnson, L Farbiak, DJ Siegwart
Nature materials 20 (5), 701-710, 2021
2992021
Combinatorial synthesis of chemically diverse core-shell nanoparticles for intracellular delivery
DJ Siegwart, KA Whitehead, L Nuhn, G Sahay, H Cheng, S Jiang, M Ma, ...
Proceedings of the National Academy of Sciences 108 (32), 12996-13001, 2011
2652011
Polystyrene with designed molecular weight distribution by atom transfer radical coupling
T Sarbu, KY Lin, J Ell, DJ Siegwart, J Spanswick, K Matyjaszewski
Macromolecules 37 (9), 3120-3127, 2004
1842004
An injectable thiol-acrylate poly (ethylene glycol) hydrogel for sustained release of methylprednisolone sodium succinate
CD Pritchard, TM O’Shea, DJ Siegwart, E Calo, DG Anderson, ...
Biomaterials 32 (2), 587-597, 2011
1782011
The polyploid state plays a tumor-suppressive role in the liver
S Zhang, K Zhou, X Luo, L Li, HC Tu, A Sehgal, LH Nguyen, Y Zhang, ...
Developmental cell 44 (4), 447-459. e5, 2018
1752018
Synthesis and biodegradation of nanogels as delivery carriers for carbohydrate drugs
JK Oh, DJ Siegwart, K Matyjaszewski
Biomacromolecules 8 (11), 3326-3331, 2007
1742007
Nanostructured hybrid hydrogels prepared by a combination of atom transfer radical polymerization and free radical polymerization
SA Bencherif, DJ Siegwart, A Srinivasan, F Horkay, JO Hollinger, ...
Biomaterials 30 (29), 5270-5278, 2009
1642009
Dendrimer‐based lipid nanoparticles deliver therapeutic FAH mRNA to normalize liver function and extend survival in a mouse model of hepatorenal tyrosinemia type I
Q Cheng, T Wei, Y Jia, L Farbiak, K Zhou, S Zhang, Y Wei, H Zhu, ...
Advanced materials 30 (52), 1805308, 2018
1632018
Synthesis of hydroxy-telechelic poly (methyl acrylate) and polystyrene by atom transfer radical coupling
T Sarbu, KY Lin, J Spanswick, RR Gil, DJ Siegwart, K Matyjaszewski
Macromolecules 37 (26), 9694-9700, 2004
1622004
Effect of molecular weight of amine end-modified poly (β-amino ester) s on gene delivery efficiency and toxicity
AA Eltoukhy, DJ Siegwart, CA Alabi, JS Rajan, R Langer, DG Anderson
Biomaterials 33 (13), 3594-3603, 2012
1522012
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