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Xiaochu Lou
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Dynamics and number of trans-SNARE complexes determine nascent fusion pore properties
H Bao, D Das, NA Courtney, Y Jiang, JS Briguglio, X Lou, D Roston, ...
Nature 554 (7691), 260-263, 2018
1102018
α-Synuclein may cross-bridge v-SNARE and acidic phospholipids to facilitate SNARE-dependent vesicle docking
X Lou, J Kim, BJ Hawk, YK Shin
Biochemical Journal 474 (12), 2039-2049, 2017
1012017
Nonaggregated α-synuclein influences SNARE-dependent vesicle docking via membrane binding
Y Lai, S Kim, J Varkey, X Lou, JK Song, J Diao, R Langen, YK Shin
Biochemistry 53 (24), 3889-3896, 2014
1012014
A fast genetically encoded fluorescent sensor for faithful in vivo acetylcholine detection in mice, fish, worms and flies
PM Borden, P Zhang, AV Shivange, JS Marvin, J Cichon, C Dan, ...
BioRxiv, 2020.02. 07.939504, 2020
792020
SNARE zippering
X Lou, YK Shin
Bioscience reports 36 (3), e00327, 2016
642016
In situ structure determination at nanometer resolution using TYGRESS
K Song, Z Shang, X Fu, X Lou, N Grigorieff, D Nicastro
Nature methods 17 (2), 201-208, 2020
552020
Multiple conformations of a single SNAREpin between two nanodisc membranes reveal diverse pre-fusion states
J Shin, X Lou, DH Kweon, YK Shin
Biochemical Journal 459 (1), 95-102, 2014
552014
Catalytic metalloporphyrin protects against paraquat neurotoxicity in vivo
C Ping, C Zhen, LI Ang, LOU Xiao-Chu, WU Xiao-Kang, Z Chun-Jun, ...
Biomedical and Environmental Sciences 21 (3), 233-238, 2008
392008
Chlamydomonas PKD2 organizes mastigonemes, hair-like glycoprotein polymers on cilia
P Liu, X Lou, JL Wingfield, J Lin, D Nicastro, K Lechtreck
Journal of Cell Biology 219 (6), e202001122, 2020
342020
Molecular origins of synaptotagmin 1 activities on vesicle docking and fusion pore opening
Y Lai, X Lou, J Diao, YK Shin
Scientific reports 5 (1), 9267, 2015
282015
Functional analysis of the interface between the tandem C2 domains of synaptotagmin-1
CS Evans, Z He, H Bai, X Lou, P Jeggle, RB Sutton, JM Edwardson, ...
Molecular biology of the cell 27 (6), 979-989, 2016
272016
The synaptotagmin 1 linker may function as an electrostatic zipper that opens for docking but closes for fusion pore opening
Y Lai, X Lou, Y Jho, TY Yoon, YK Shin
Biochemical Journal 456 (1), 25-33, 2013
262013
Phosphatidylinositol 4, 5-bisphosphate drives Ca2+-independent membrane penetration by the tandem C2 domain proteins synaptotagmin-1 and Doc2β
MM Bradberry, H Bao, X Lou, ER Chapman
Journal of Biological Chemistry 294 (28), 10942-10953, 2019
242019
Structural and kinetic analysis of Saccharomyces cerevisiae thioredoxin Trx1: implications for the catalytic mechanism of GSSG reduced by the thioredoxin system
R Bao, Y Zhang, X Lou, CZ Zhou, Y Chen
Biochimica et Biophysica Acta (BBA)-Proteins and Proteomics 1794 (8), 1218-1223, 2009
242009
Synaptotagmin 1 and Ca2+ drive trans SNARE zippering
Y Lai, X Lou, C Wang, T Xia, J Tong
Scientific reports 4 (1), 4575, 2014
232014
Synaptotagmin-1 is an antagonist for Munc18-1 in SNARE zippering
X Lou, J Shin, Y Yang, J Kim, YK Shin
Journal of Biological Chemistry 290 (16), 10535-10543, 2015
202015
Lipid molecules influence early stages of yeast SNARE-mediated membrane fusion
Y Lai, L Zhao, B Bu, X Lou, D Li, B Ji, J Liu, J Diao, YK Shin
Physical biology 12 (2), 025003, 2015
152015
Structure of the ciliary axoneme at nanometer resolution reconstructed by TYGRESS
K Song, Z Shang, X Fu, X Lou, N Grigorieff, D Nicastro
BioRxiv, 363317, 2018
122018
Structure of the thioredoxin-fold domain of human phosducin-like protein 2
X Lou, R Bao, CZ Zhou, Y Chen
Acta Crystallographica Section F: Structural Biology and Crystallization …, 2009
122009
Purification, crystallization and preliminary X-ray diffraction analysis of glutathionylated Trx1 C33S mutant from yeast
X Lou, Y Zhang, R Bao, CZ Zhou, Y Chen
Acta Crystallographica Section F: Structural Biology and Crystallization …, 2009
22009
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Articles 1–20