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Matthew F. Wipperman
Matthew F. Wipperman
Quantitative Translational Scientist, Regeneron Pharmaceuticals
Adresse e-mail validée de regeneron.com - Page d'accueil
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Antibiotic treatment for Tuberculosis induces a profound dysbiosis of the microbiome that persists long after therapy is completed
MF Wipperman, DW Fitzgerald, MAJ Juste, Y Taur, S Namasivayam, ...
Scientific reports 7 (1), 10767, 2017
1752017
Pathogen roid rage: Cholesterol utilization by Mycobacterium tuberculosis
MF Wipperman, NS Sampson, ST Thomas
Critical Reviews in Biochemistry and Molecular Biology 49 (4), 269-293, 2014
1732014
Dupilumab in adults and adolescents with eosinophilic esophagitis
ES Dellon, ME Rothenberg, MH Collins, I Hirano, M Chehade, ...
New England Journal of Medicine 387 (25), 2317-2330, 2022
1512022
Longitudinal profiling reveals a persistent intestinal dysbiosis triggered by conventional anti-tuberculosis therapy
S Namasivayam, M Maiga, W Yuan, V Thovarai, DL Costa, LR Mittereder, ...
Microbiome 5, 1-17, 2017
1392017
Shrinking the FadE proteome of Mycobacterium tuberculosis: insights into cholesterol metabolism through identification of an α2β2 heterotetrameric acyl coenzyme A dehydrogenase …
MF Wipperman, M Yang, ST Thomas, NS Sampson
Journal of Bacteriology 195 (19), 4331-4341, 2013
752013
The microbiome and tuberculosis: early evidence for cross talk
S Namasivayam, A Sher, MS Glickman, MF Wipperman
MBio 9 (5), 10.1128/mbio. 01420-18, 2018
72*2018
Mucosal-associated invariant and γδ T cell subsets respond to initial Mycobacterium tuberculosis infection
CK Vorkas, MF Wipperman, K Li, J Bean, SK Bhattarai, M Adamow, ...
JCI insight 3 (19), 2018
672018
Unraveling Cholesterol Catabolism in Mycobacterium tuberculosis: ChsE4-ChsE5 α2β2 Acyl-CoA Dehydrogenase Initiates β-Oxidation of 3-Oxo-cholest-4-en-26 …
M Yang, R Lu, KE Guja, MF Wipperman, JR St. Clair, AC Bonds, ...
ACS infectious diseases 1 (2), 110-125, 2015
662015
An antibiotic-impacted microbiota compromises the development of colonic regulatory T cells and predisposes to dysregulated immune responses
X Zhang, TC Borbet, A Fallegger, MF Wipperman, MJ Blaser, A Müller
Mbio 12 (1), 10.1128/mbio. 03335-20, 2021
342021
Gastrointestinal microbiota composition predicts peripheral inflammatory state during treatment of human tuberculosis
MF Wipperman, SK Bhattarai, CK Vorkas, VS Maringati, Y Taur, ...
Nature communications 12 (1), 1141, 2021
322021
Mammalian target of rapamycin: a metabolic rheostat for regulating adipose tissue function and cardiovascular health
MF Wipperman, DC Montrose, AM Gotto Jr, DP Hajjar
The American Journal of Pathology 189 (3), 492-501, 2019
302019
Mycobacterial mutagenesis and drug resistance are controlled by phosphorylation-and cardiolipin-mediated inhibition of the RecA coprotease
MF Wipperman, BE Heaton, A Nautiyal, O Adefisayo, H Evans, R Gupta, ...
Molecular cell 72 (1), 152-161. e7, 2018
262018
Influence of the early-life gut microbiota on the immune responses to an inhaled allergen
TC Borbet, MB Pawline, X Zhang, MF Wipperman, S Reuter, T Maher, J Li, ...
Mucosal immunology 15 (5), 1000-1011, 2022
192022
Baseline severe acute respiratory syndrome viral load is associated with coronavirus disease 2019 severity and clinical outcomes: post hoc analyses of a phase 2/3 trial
A Boyapati, MF Wipperman, PJ Ehmann, S Hamon, DJ Lederer, ...
The Journal of Infectious Diseases 224 (11), 1830-1838, 2021
152021
The activin/FLRG pathway associates with poor COVID-19 outcomes in hospitalized patients
M McAleavy, Q Zhang, PJ Ehmann, J Xu, MF Wipperman, D Ajithdoss, ...
Molecular and Cellular Biology 42 (1), e00467-21, 2022
12*2022
Antibiotic treatment for tuberculosis induces a profound dysbiosis of the microbiome that persists long after therapy is completed. Sci Rep 7: 10767
MF Wipperman, DW Fitzgerald, MAJ Juste, Y Taur, S Namasivayam, ...
122017
Elevated serum IgA following vaccination against SARS-CoV-2 in a cohort of high-risk first responders
BT Montague, MF Wipperman, E Chio, R Crow, AT Hooper, MP O’Brien, ...
Scientific Reports 12 (1), 14932, 2022
112022
IpdE1-IpdE2 is a heterotetrameric acyl coenzyme A dehydrogenase that is widely distributed in steroid-degrading bacteria
JE Gadbery, JW Round, T Yuan, MF Wipperman, KT Story, AM Crowe, ...
Biochemistry 59 (10), 1113-1123, 2020
112020
Anti-SARS-CoV-2 IgA identifies asymptomatic infection in first responders
BT Montague, MF Wipperman, AT Hooper, SC Hamon, R Crow, F Elemo, ...
The Journal of Infectious Diseases 225 (4), 578-586, 2022
102022
Dupilumab normalizes the eosinophilic esophagitis disease transcriptome in adult patients with eosinophilic esophagitis
JD Hamilton, WK Lim, SC Hamon, ME Rothenberg, MH Collins, ...
Gastroenterology 158 (6), S835-S835, 2020
92020
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