Benjamin Housden
Benjamin Housden
Living Systems Institute, University of Exeter
Adresse e-mail validée de exeter.ac.uk
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Highly efficient Cas9-mediated transcriptional programming
A Chavez, J Scheiman, S Vora, BW Pruitt, M Tuttle, EPR Iyer, S Lin, ...
Nature methods 12 (4), 326, 2015
7982015
Optimized gene editing technology for Drosophila melanogaster using germ line-specific Cas9
X Ren, J Sun, BE Housden, Y Hu, C Roesel, S Lin, LP Liu, Z Yang, D Mao, ...
Proceedings of the National Academy of Sciences 110 (47), 19012-19017, 2013
2982013
Comparison of Cas9 activators in multiple species
A Chavez, M Tuttle, BW Pruitt, B Ewen-Campen, R Chari, ...
Nature methods 13 (7), 563, 2016
2942016
Seipin is required for converting nascent to mature lipid droplets
H Wang, M Becuwe, BE Housden, C Chitraju, AJ Porras, MM Graham, ...
Elife 5, 2016
1692016
Direct response to Notch activation: signaling crosstalk and incoherent logic
A Krejčí, F Bernard, BE Housden, S Collins, SJ Bray
Sci. Signal. 2 (55), ra1-ra1, 2009
1602009
Loss-of-function genetic tools for animal models: cross-species and cross-platform differences
BE Housden, M Muhar, M Gemberling, CA Gersbach, DYR Stainier, ...
Nature Reviews Genetics 18 (1), 24, 2017
1112017
In vivo transcriptional activation using CRISPR/Cas9 in Drosophila
S Lin, B Ewen-Campen, X Ni, BE Housden, N Perrimon
Genetics 201 (2), 433-442, 2015
892015
Identification of potential drug targets for tuberous sclerosis complex by synthetic screens combining CRISPR-based knockouts with RNAi
BE Housden, AJ Valvezan, C Kelley, R Sopko, Y Hu, C Roesel, S Lin, ...
Sci. Signal. 8 (393), rs9-rs9, 2015
882015
Specificity of Notch pathway activation: twist controls the transcriptional output in adult muscle progenitors
F Bernard, A Krejci, B Housden, B Adryan, SJ Bray
Development 137 (16), 2633-2642, 2010
672010
A gene-specific T2A-GAL4 library for Drosophila
PT Lee, J Zirin, O Kanca, WW Lin, KL Schulze, D Li-Kroeger, R Tao, ...
Elife 7, e35574, 2018
612018
Resources for functional genomics studies in Drosophila melanogaster
SE Mohr, Y Hu, K Kim, BE Housden, N Perrimon
Genetics 197 (1), 1-18, 2014
582014
mTORC1 Couples Nucleotide Synthesis to Nucleotide Demand Resulting in a Targetable Metabolic Vulnerability
AJ Valvezan, M Turner, A Belaid, HC Lam, SK Miller, MC McNamara, ...
Cancer Cell, 2017
562017
Transcriptional dynamics elicited by a short pulse of notch activation involves feed-forward regulation by E (spl)/Hes genes
BE Housden, AQ Fu, A Krejci, F Bernard, B Fischer, S Tavaré, S Russell, ...
PLoS genetics 9 (1), e1003162, 2013
552013
CRISPR guide RNA design for research applications
SE Mohr, Y Hu, B Ewen‐Campen, BE Housden, R Viswanatha, ...
The FEBS journal 283 (17), 3232-3238, 2016
502016
Drosophila reporter vectors compatible with ΦC31 integrase transgenesis techniques and their use to generate new Notch reporter fly lines
BE Housden, K Millen, SJ Bray
G3: Genes| Genomes| Genetics 2 (1), 79-82, 2012
492012
Spatial and temporal organization of signaling pathways
BE Housden, N Perrimon
Trends in biochemical sciences 39 (10), 457-464, 2014
432014
Comparing CRISPR and RNAi-based screening technologies
BE Housden, N Perrimon
Nature biotechnology 34 (6), 621-623, 2016
282016
Cas9-based genome editing in Drosophila
BE Housden, S Lin, N Perrimon
Methods Enzymol 546, 415-439, 2014
282014
Mapping signaling pathway cross-talk in Drosophila cells
N Ammeux, BE Housden, A Georgiadis, Y Hu, N Perrimon
Proceedings of the National Academy of Sciences 113 (35), 9940-9945, 2016
262016
Drosophila p53 controls Notch expression and balances apoptosis and proliferation
R Simón, R Aparicio, BE Housden, S Bray, A Busturia
Apoptosis 19 (10), 1430-1443, 2014
252014
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