| A Quantitative Systems Pharmacology Model of Gaucher Disease Type 1 Provides Mechanistic Insight Into the Response to Substrate Reduction Therapy With Eliglustat R Abrams, CD Kaddi, M Tao, RJ Leiser, G Simoni, F Reali, J Tolsma, ... CPT: pharmacometrics & systems pharmacology 9 (7), 374-383, 2020 | 17 | 2020 |
| Linear-in-flux-expressions methodology: Toward a robust mathematical framework for quantitative systems pharmacology simulators ST McQuade, RE Abrams, JS Barrett, B Piccoli, K Azer Gene regulation and systems biology 11, 1177625017711414, 2017 | 14 | 2017 |
| A quantitative systems pharmacology platform to investigate the impact of alirocumab and cholesterol-lowering therapies on lipid profiles and plaque characteristics JE Ming, RE Abrams, DW Bartlett, M Tao, T Nguyen, H Surks, K Kudrycki, ... Gene regulation and systems biology 11, 1177625017710941, 2017 | 14 | 2017 |
| Integrated quantitative systems pharmacology (QSP) model of lysosomal diseases provides an innovative computational platform to support research and therapeutic development for … C Kaddi, F Reali, L Marchetti, B Niesner, S Parolo, G Simoni, S Zaph, ... | 8 | 2018 |
| Stability of metabolic networks via Linear-in-Flux-Expressions NJ Merrill, Z An, ST McQuade, F Garin, K Azer, RE Abrams, B Piccoli arXiv preprint arXiv:1808.08263, 2018 | 5 | 2018 |
| Equilibria for large metabolic systems and the life approach ST McQuade, Z An, NJ Merrill, RE Abrams, K Azer, B Piccoli 2018 Annual American Control Conference (ACC), 2005-2010, 2018 | 4 | 2018 |
| PREDICTING DRUG EFFICACY AND CYTOKINE RELEASE WITH A VERSATILE QUANTITATIVE SYSTEMS PHARMACOLOGY (QSP) MODELING STRATEGY FOR MULTISPECIFIC T-CELL ENGAGERS. R Abrams, K Pierre, N El-Murr, A Li, J Fretland, J Li, L Wu, E Seung, ... CLINICAL PHARMACOLOGY & THERAPEUTICS 107, S114-S114, 2020 | | 2020 |
| Development of an Integrated Human Model of Electrophysiology and Actin-Myosin Binding to Describe Sarcomere Force Generation in Cardiomyocytes RE Abrams, HC Schneider, T Radziun, B Goebel, L Lucats, K Azer, ... Biophysical Journal 116 (3), 422a-423a, 2019 | | 2019 |
| Development of a multiscale model for heart failure focusing on cardiac myosin modulators SK Stamatelos, R Abrams, E Sobie, L Lucats, H Surks, ... JOURNAL OF PHARMACOKINETICS AND PHARMACODYNAMICS 45, S125-S125, 2018 | | 2018 |
