PfCRT and its role in antimalarial drug resistance A Ecker, AM Lehane, J Clain, DA Fidock Trends in parasitology 28 (11), 504-514, 2012 | 346 | 2012 |
Combined Deletions of pfhrp2 and pfhrp3 Genes Result in Plasmodium falciparum Malaria False-Negative Rapid Diagnostic Test S Houzé, V Hubert, G Le Pessec, J Le Bras, J Clain Journal of clinical microbiology 49 (7), 2694-2696, 2011 | 102 | 2011 |
Artemisinin bioactivity and resistance in malaria parasites AM Talman, J Clain, R Duval, R Ménard, F Ariey Trends in parasitology 35 (12), 953-963, 2019 | 100 | 2019 |
A Shared Asian Origin of the Triple-Mutant dhfr Allele in Plasmodium falciparum from Sites across Africa O Maïga, AA Djimdé, V Hubert, E Renard, A Aubouy, F Kironde, B Nsimba, ... The Journal of infectious diseases 196 (1), 165-172, 2007 | 98 | 2007 |
Les résistances aux médicaments antipaludiques J Le Bras, L Musset, J Clain Médecine et maladies infectieuses 36 (8), 401-405, 2006 | 71* | 2006 |
Chemotherapy of malaria JM Vinetz, J Clain, V Bounkeua, RT Eastman, D Fidock The pharmacological basis of therapeutics 12, 1383-418, 2011 | 70 | 2011 |
Parallel Evolution of Adaptive Mutations in Plasmodium falciparum Mitochondrial DNA During Atovaquone-Proguanil Treatment L Musset, J Le Bras, J Clain Molecular biology and evolution 24 (8), 1582-1585, 2007 | 67 | 2007 |
Two mild cystic fibrosis-associated mutations result in severe cystic fibrosis when combined in cis and reveal a residue important for cystic fibrosis transmembrane conductance … J Clain, J Fritsch, J Lehmann-Che, M Bali, N Arous, M Goossens, ... Journal of Biological Chemistry 276 (12), 9045-9049, 2001 | 59 | 2001 |
Structure‐function analysis of a double‐mutant cystic fibrosis transmembrane conductance regulator protein occurring in disorders related to cystic fibrosis P Fanen, J Clain, R Labarthe, P Hulin, E Girodon, P Pagesy, M Goossens, ... FEBS letters 452 (3), 371-374, 1999 | 50 | 1999 |
The antimalarial drug primaquine targets Fe–S cluster proteins and yeast respiratory growth A Lalève, C Vallières, MP Golinelli-Cohen, C Bouton, Z Song, G Pawlik, ... Redox biology 7, 21-29, 2016 | 49 | 2016 |
Emergence of resistance to atovaquone-proguanil in malaria parasites: insights from computational modeling and clinical case reports G Cottrell, L Musset, V Hubert, J Le Bras, J Clain Antimicrobial agents and chemotherapy 58 (8), 4504-4514, 2014 | 46 | 2014 |
Comparative structural and evolutionary analyses predict functional sites in the artemisinin resistance malaria protein K13 R Coppée, DC Jeffares, MA Miteva, A Sabbagh, J Clain Scientific reports 9 (1), 10675, 2019 | 45 | 2019 |
Membrane cholesterol content modulates ClC-2 gating and sensitivity to oxidative stress A Hinzpeter, J Fritsch, F Borot, S Trudel, DL Vieu, F Brouillard, ... Journal of biological chemistry 282 (4), 2423-2432, 2007 | 45 | 2007 |
Misprocessing of the CFTR protein leads to mild cystic fibrosis phenotype J Clain, J Lehmann‐Che, I Duguépéroux, N Arous, E Girodon, ... Human mutation 25 (4), 360-371, 2005 | 38 | 2005 |
Pneumocystis Cytochrome b Mutants Associated With Atovaquone Prophylaxis Failure as the Cause of Pneumocystis Infection Outbreak Among Heart Transplant … N Argy, S Le Gal, R Coppée, Z Song, W Vindrios, L Massias, WC Kao, ... Clinical Infectious Diseases 67 (6), 913-919, 2018 | 29 | 2018 |
A neutral variant involved in a complex CFTR allele contributes to a severe cystic fibrosis phenotype J Clain, J Lehmann-Che, E Girodon, J Lipecka, A Edelman, M Goossens, ... Human genetics 116, 454-460, 2005 | 29 | 2005 |
Plasmodium falciparum sexual parasites regulate infected erythrocyte permeability G Bouyer, D Barbieri, F Dupuy, A Marteau, A Sissoko, ME N’dri, G Neveu, ... Communications Biology 3 (1), 726, 2020 | 23 | 2020 |
Structural and evolutionary analyses of the Plasmodium falciparum chloroquine resistance transporter R Coppée, A Sabbagh, J Clain Scientific reports 10 (1), 4842, 2020 | 22 | 2020 |
Adaptive Differentiation of Plasmodium falciparum Populations Inferred from Single-Nucleotide Polymorphisms (SNPs) Conferring Drug Resistance and from … O Maïga-Ascofaré, J Le Bras, R Mazmouz, E Renard, S Falcão, ... The Journal of infectious diseases 202 (7), 1095-1103, 2010 | 21 | 2010 |
Mutation in the Plasmodium falciparum BTB/POZ domain of K13 protein confers artemisinin resistance L Paloque, R Coppée, BH Stokes, NF Gnädig, K Niaré, JM Augereau, ... Antimicrobial Agents and Chemotherapy 66 (1), e01320-21, 2022 | 18 | 2022 |