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Darren D Thomson
Darren D Thomson
Senior Experimental Officer, University of Exeter
Adresse e-mail validée de exeter.ac.uk - Page d'accueil
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Contact‐induced apical asymmetry drives the thigmotropic responses of Candida albicans hyphae
DD Thomson, S Wehmeier, FRJ Byfield, PA Janmey, D Caballero‐Lima, ...
Cellular microbiology 17 (3), 342-354, 2015
692015
Inducible cell fusion permits use of competitive fitness profiling in the human pathogenic fungus Aspergillus fumigatus
D Macdonald, DD Thomson, A Johns, AC Valenzuela, JM Gilsenan, ...
Antimicrobial agents and chemotherapy 63 (1), 2019
282019
Mechanical force-induced morphology changes in a human fungal pathogen
C Puerner, N Kukhaleishvili, D Thomson, S Schaub, X Noblin, ...
BMC biology 18, 1-21, 2020
202020
High frame-rate resolution of cell division during Candida albicans filamentation
DD Thomson, J Berman, AC Brand
Fungal Genetics and Biology 88, 54-58, 2016
202016
Targeting methionine synthase in a fungal pathogen causes a metabolic imbalance that impacts cell energetics, growth, and virulence
J Scott, M Sueiro-Olivares, BP Thornton, RA Owens, H Muhamadali, ...
MBio 11 (5), 10.1128/mbio. 01985-20, 2020
152020
Characterisation of Aspergillus fumigatus Endocytic Trafficking within Airway Epithelial Cells Using High-Resolution Automated Quantitative Confocal Microscopy
N Ben-Ghazzi, S Moreno-Velásquez, C Seidel, D Thomson, DW Denning, ...
Journal of Fungi 7 (6), 454, 2021
132021
Novel Insights into Aspergillus fumigatus Pathogenesis and Host Response from State-of-the-Art Imaging of Host–Pathogen Interactions during Infection
SC Ortiz, K Pennington, DD Thomson, M Bertuzzi
Journal of Fungi 8 (3), 264, 2022
92022
Fungal and host protein persulfidation are functionally correlated and modulate both virulence and antifungal response
M Sueiro-Olivares, J Scott, S Gago, D Petrovic, E Kouroussis, J Zivanovic, ...
PLoS Biology 19 (6), e3001247, 2021
82021
Courtship ritual of male and female nuclei during fertilization in Neurospora crassa
S Brun, HC Kuo, CE Jeffree, DD Thomson, N Read
Microbiology spectrum 9 (2), e00335-21, 2021
72021
Bacillus Calmette–Guérin-induced human mast cell activation relies on IL-33 priming
KM Garcia-Rodriguez, A Goenka, DD Thomson, R Bahri, C Tontini, ...
International Journal of Molecular Sciences 23 (14), 7549, 2022
62022
Epithelial uptake of Aspergillus fumigatus drives efficient fungal clearance in vivo and is aberrant in Chronic Obstructive Pulmonary Disease (COPD)
M Bertuzzi, GJ Howell, DD Thomson, R Fortune-Grant, A Möslinger, ...
bioRxiv, 2022.02. 01.478664, 2022
62022
Live-cell imaging of rapid calcium dynamics using fluorescent, genetically-encoded GCaMP probes with Aspergillus fumigatus
A Muñoz, M Bertuzzi, C Seidel, D Thomson, EM Bignell, ND Read
Fungal Genetics and Biology 151, 103470, 2021
62021
Heightened Efficacy of Anidulafungin When Used in Combination with Manogepix or 5-Flucytosine against Candida auris In Vitro
LLH John, DD Thomson, T Bicanic, M Hoenigl, AJP Brown, TS Harrison, ...
Antimicrobial agents and chemotherapy 67 (6), e01645-22, 2023
52023
Aspergillus fumigatus drives tissue damage via iterative assaults upon mucosal integrity and immune homeostasis
UJ Okaa, M Bertuzzi, R Fortune-Grant, DD Thomson, DL Moyes, ...
Infection and Immunity 91 (2), e00333-22, 2023
52023
Distinct cohorts of Aspergillus fumigatus transcription factors are required for epithelial damage occurring via contact-or soluble effector-mediated mechanisms
S Rahman, N van Rhijn, P Papastamoulis, DD Thomson, Z Carter, ...
Frontiers in cellular and infection Microbiology 12, 907519, 2022
22022
Cryptococcus neoformans rapidly invades the murine brain by sequential breaching of airway and endothelial tissues barriers, followed by engulfment by microglia
VI Francis, C Liddle, E Camacho, M Kulkarni, SRS Junior, JA Harvey, ...
Mbio 15 (4), e03078-23, 2024
12024
Automated Quantitative Analysis of Airway Epithelial Cell Detachment Upon Fungal Challenge
S Rahman, DD Thomson, M Bertuzzi
Host-Fungal Interactions: Methods and Protocols, 225-239, 2021
12021
Correction for Macdonald et al., “Inducible Cell Fusion Permits Use of Competitive Fitness Profiling in the Human Pathogenic Fungus Aspergillus fumigatus
D Macdonald, DD Thomson, A Johns, AC Valenzuela, JM Gilsenan, ...
Antimicrobial Agents and Chemotherapy 63 (6), 10.1128/aac. 00706-19, 2019
12019
Aspergillus-mediated allergic airway inflammation is triggered by dendritic cell recognition of a defined spore morphotype, a process that can be targeted via antifungal …
EL Houlder, S Gago, G Vere, D Conn, S Khan, D Thomson, M Shepherd, ...
bioRxiv, 2024.01. 11.575032, 2024
2024
Epithelial uptake ofAspergillus fumigatusdrives efficient fungal clearancein vivoand is aberrant in Chronic Obstructive Pulmonary Disease (COPD)
M Bertuzzi, G Howell, D Thomson, R Fortune-Grant, A Möslinger, ...
2022
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