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Elena Pugacheva
Elena Pugacheva
Associate Professot West Virginia University
Adresse e-mail validée de mix.wvu.edu
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Restoration of the tumor suppressor function to mutant p53 by a low-molecular-weight compound
VJN Bykov, N Issaeva, A Shilov, M Hultcrantz, E Pugacheva, P Chumakov, ...
Nature medicine 8 (3), 282-288, 2002
12852002
HEF1-dependent Aurora A activation induces disassembly of the primary cilium
EN Pugacheva, SA Jablonski, TR Hartman, EP Henske, EA Golemis
Cell 129 (7), 1351-1363, 2007
9552007
The focal adhesion scaffolding protein HEF1 regulates activation of the Aurora-A and Nek2 kinases at the centrosome
EN Pugacheva, EA Golemis
Nature cell biology 7 (10), 937-946, 2005
2702005
Primary cilia and the cell cycle
OV Plotnikova, EN Pugacheva, EA Golemis
Methods in cell biology 94, 137-160, 2009
2612009
HEF1 is a necessary and specific downstream effector of FAK that promotes the migration of glioblastoma cells
M Natarajan, JE Stewart, EA Golemis, EN Pugacheva, K Alexandropoulos, ...
Oncogene 25 (12), 1721-1732, 2006
2372006
Cell cycle–dependent ciliogenesis and cancer
OV Plotnikova, EA Golemis, EN Pugacheva
Cancer research 68 (7), 2058-2061, 2008
1982008
Calmodulin activation of Aurora-A kinase (AURKA) is required during ciliary disassembly and in mitosis
OV Plotnikova, AS Nikonova, YV Loskutov, PY Kozyulina, EN Pugacheva, ...
Molecular biology of the cell 23 (14), 2658-2670, 2012
1762012
NEDD9 promotes oncogenic signaling in mammary tumor development
E Izumchenko, MK Singh, OV Plotnikova, N Tikhmyanova, JL Little, ...
Cancer research 69 (18), 7198-7206, 2009
1522009
Novel gain of function activity of p53 mutants: activation of the dUTPase gene expression leading to resistance to 5-fluorouracil
EN Pugacheva, AV Ivanov, JE Kravchenko, BP Kopnin, AJ Levine, ...
Oncogene 21 (30), 4595-4600, 2002
1232002
KAP1 promotes proliferation and metastatic progression of breast cancer cells
JB Addison, C Koontz, JH Fugett, CJ Creighton, D Chen, MK Farrugia, ...
Cancer research 75 (2), 344-355, 2015
1182015
Rapid calcium-dependent activation of Aurora-A kinase
OV Plotnikova, EN Pugacheva, RL Dunbrack, EA Golemis
Nature communications 1 (1), 64, 2010
942010
HEF1-aurora A interactions: points of dialog between the cell cycle and cell attachment signaling networks
EN Pugacheva, EA Golemis
Cell Cycle 5 (4), 384-391, 2006
892006
Aurora A kinase activity influences calcium signaling in kidney cells
OV Plotnikova, EN Pugacheva, EA Golemis
Journal of Cell Biology 193 (6), 1021-1032, 2011
832011
Interdependence of cell attachment and cell cycle signaling
EN Pugacheva, F Roegiers, EA Golemis
Current opinion in cell biology 18 (5), 507-515, 2006
802006
Deregulation of HEF1 impairs M-phase progression by disrupting the RhoA activation cycle
D Dadke, M Jarnik, EN Pugacheva, MK Singh, EA Golemis
Molecular biology of the cell 17 (3), 1204-1217, 2006
692006
Role for chondroitin sulfate glycosaminoglycan in NEDD9-mediated breast cancer cell growth
J Iida, J Dorchak, R Clancy, J Slavik, R Ellsworth, Y Katagiri, ...
Experimental cell research 330 (2), 358-370, 2015
612015
LPA signaling is regulated through the primary cilium: a novel target in glioblastoma
YV Loskutov, CL Griffin, KM Marinak, A Bobko, NV Margaryan, ...
Oncogene 37 (11), 1457-1471, 2018
542018
NEDD9 stabilizes focal adhesions, increases binding to the extra-cellular matrix and differentially effects 2D versus 3D cell migration
J Zhong, JB Baquiran, N Bonakdar, J Lees, YW Ching, E Pugacheva, ...
PloS one 7 (4), e35058, 2012
522012
AF1q is a novel TCF7 co-factor which activates CD44 and promotes breast cancer metastasis
J Park, M Schlederer, M Schreiber, R Ice, O Merkel, M Bilban, S Hofbauer, ...
Oncotarget 6 (24), 20697, 2015
462015
NEDD9 depletion destabilizes Aurora A kinase and heightens the efficacy of Aurora A inhibitors: implications for treatment of metastatic solid tumors
RJ Ice, SL McLaughlin, RH Livengood, MV Culp, ER Eddy, AV Ivanov, ...
Cancer research 73 (10), 3168-3180, 2013
462013
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