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David Toczyski
David Toczyski
Professor of Biochemistry, UCSF
Adresse e-mail validée de ucsf.edu
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Functional dissection of protein complexes involved in yeast chromosome biology using a genetic interaction map
SR Collins, KM Miller, NL Maas, A Roguev, J Fillingham, CS Chu, ...
Nature 446 (7137), 806-810, 2007
10222007
When checkpoints fail
AG Paulovich, DP Toczyski, LH Hartwell
Cell 88 (3), 315-321, 1997
8991997
A unified view of the DNA-damage checkpoint
J Melo, D Toczyski
Current opinion in cell biology 14 (2), 237-245, 2002
6232002
CDC5 and CKII control adaptation to the yeast DNA damage checkpoint
DP Toczyski, DJ Galgoczy, LH Hartwell
Cell 90 (6), 1097-1106, 1997
5351997
Two checkpoint complexes are independently recruited to sites of DNA damage in vivo
JA Melo, J Cohen, DP Toczyski
Genes & development 15 (21), 2809-2821, 2001
4962001
Cell cycle and checkpoint regulation of histone H3 K56 acetylation by Hst3 and Hst4
NL Maas, KM Miller, LG DeFazio, DP Toczyski
Molecular cell 23 (1), 109-119, 2006
2912006
Securin and B-cyclin/CDK are the only essential targets of the APC
BR Thornton, DP Toczyski
Nature cell biology 5 (12), 1090-1094, 2003
2532003
Damage-induced phosphorylation of Sld3 is important to block late origin firing
J Lopez-Mosqueda, NL Maas, ZO Jonsson, LG DeFazio-Eli, ...
Nature 467 (7314), 479-483, 2010
2292010
Colocalization of sensors is sufficient to activate the DNA damage checkpoint in the absence of damage
CY Bonilla, JA Melo, DP Toczyski
Molecular cell 30 (3), 267-276, 2008
2202008
The Epstein-Barr virus (EBV) small RNA EBER1 binds and relocalizes ribosomal protein L22 in EBV-infected human B lymphocytes.
DP Toczyski, AG Matera, DC Ward, JA Steitz
Proceedings of the National Academy of Sciences 91 (8), 3463-3467, 1994
2171994
An architectural map of the anaphase-promoting complex
BR Thornton, TM Ng, ME Matyskiela, CW Carroll, DO Morgan, ...
Genes & development 20 (4), 449-460, 2006
2012006
Precise destruction: an emerging picture of the APC
BR Thornton, DP Toczyski
Genes & development 20 (22), 3069-3078, 2006
2002006
DNA breaks promote genomic instability by impeding proper chromosome segregation
JA Kaye, JA Melo, SK Cheung, MB Vaze, JE Haber, DP Toczyski
Current Biology 14 (23), 2096-2106, 2004
2002004
Cross‐species chemogenomic profiling reveals evolutionarily conserved drug mode of action
L Kapitzky, P Beltrao, TJ Berens, N Gassner, C Zhou, A Wüster, J Wu, ...
Molecular systems biology 6 (1), 451, 2010
1752010
Complicated tails: histone modifications and the DNA damage response
GM Vidanes, CY Bonilla, DP Toczyski
Cell 121 (7), 973-976, 2005
1732005
EAP, a highly conserved cellular protein associated with Epstein‐Barr virus small RNAs (EBERs).
DP Toczyski, JA Steitz
The EMBO journal 10 (2), 459-466, 1991
1391991
Checkpoint adaptation precedes spontaneous and damage-induced genomic instability in yeast
DJ Galgoczy, DP Toczyski
Molecular and cellular biology 21 (5), 1710-1718, 2001
1262001
A proteomic screen reveals SCFGrr1 targets that regulate the glycolytic–gluconeogenic switch
JA Benanti, SK Cheung, MC Brady, DP Toczyski
Nature cell biology 9 (10), 1184-1191, 2007
1102007
Acetylome profiling reveals overlap in the regulation of diverse processes by sirtuins, gcn5, and esa1
M Downey, JR Johnson, NE Davey, BW Newton, TL Johnson, S Galaang, ...
Molecular & Cellular Proteomics 14 (1), 162-176, 2015
782015
CDC5 inhibits the hyperphosphorylation of the checkpoint kinase Rad53, leading to checkpoint adaptation
GM Vidanes, FD Sweeney, S Galicia, S Cheung, JP Doyle, D Durocher, ...
PLoS biology 8 (1), e1000286, 2010
712010
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