| Phosphorylation of the FUS low‐complexity domain disrupts phase separation, aggregation, and toxicity Z Monahan, VH Ryan, AM Janke, KA Burke, SN Rhoads, GH Zerze, ... The EMBO journal 36 (20), 2951-2967, 2017 | 584 | 2017 |
| Phase separation of C9orf72 dipeptide repeats perturbs stress granule dynamics S Boeynaems, E Bogaert, D Kovacs, A Konijnenberg, E Timmerman, ... Molecular cell 65 (6), 1044-1055. e5, 2017 | 493 | 2017 |
| Mechanistic view of hnRNPA2 low-complexity domain structure, interactions, and phase separation altered by mutation and arginine methylation VH Ryan, GL Dignon, GH Zerze, CV Chabata, R Silva, AE Conicella, ... Molecular cell 69 (3), 465-479. e7, 2018 | 338 | 2018 |
| A single N‐terminal phosphomimic disrupts TDP‐43 polymerization, phase separation, and RNA splicing A Wang, AE Conicella, HB Schmidt, EW Martin, SN Rhoads, AN Reeb, ... The EMBO journal 37 (5), e97452, 2018 | 325 | 2018 |
| SARS‐CoV‐2 nucleocapsid protein phase‐separates with RNA and with human hnRNPs TM Perdikari, AC Murthy, VH Ryan, S Watters, MT Naik, NL Fawzi The EMBO journal 39 (24), e106478, 2020 | 204 | 2020 |
| Physiological, pathological, and targetable membraneless organelles in neurons VH Ryan, NL Fawzi Trends in neurosciences 42 (10), 693-708, 2019 | 101 | 2019 |
| Cutting edge: evidence for a dynamically driven T cell signaling mechanism WF Hawse, MM Champion, MV Joyce, LM Hellman, M Hossain, V Ryan, ... The Journal of Immunology 188 (12), 5819-5823, 2012 | 87 | 2012 |
| Coordinated gene expression of neuroinflammatory and cell signaling markers in dorsolateral prefrontal cortex during human brain development and aging CT Primiani, VH Ryan, JS Rao, MC Cam, K Ahn, HR Modi, SI Rapoport PLoS One 9 (10), e110972, 2014 | 54 | 2014 |
| SARS-CoV-2 nucleocapsid protein undergoes liquid-liquid phase separation stimulated by RNA and partitions into phases of human ribonucleoproteins. TM Perdikari, AC Murthy, VH Ryan, S Watters, MT Naik, NL Fawzi BioRxiv, 2020 | 49 | 2020 |
| Tyrosine phosphorylation regulates hnRNPA2 granule protein partitioning and reduces neurodegeneration VH Ryan, TM Perdikari, MT Naik, CF Saueressig, J Lins, GL Dignon, ... The EMBO Journal 40 (3), e105001, 2021 | 47 | 2021 |
| The SH3 domain of Fyn kinase interacts with and induces liquid–liquid phase separation of the low-complexity domain of hnRNPA2 J Amaya, VH Ryan, NL Fawzi Journal of Biological Chemistry 293 (51), 19522-19531, 2018 | 41 | 2018 |
| Epigenetic cell fate in Candida albicans is controlled by transcription factor condensates acting at super-enhancer-like elements C Frazer, MI Staples, Y Kim, M Hirakawa, MA Dowell, NV Johnson, ... Nature microbiology 5 (11), 1374-1389, 2020 | 40 | 2020 |
| Mis-spliced transcripts generate de novo proteins in TDP-43–related ALS/FTD S Seddighi, YA Qi, AL Brown, OG Wilkins, C Bereda, C Belair, YJ Zhang, ... Science Translational Medicine 16 (734), eadg7162, 2024 | 37 | 2024 |
| Coordination of gene expression of arachidonic and docosahexaenoic acid cascade enzymes during human brain development and aging VH Ryan, CT Primiani, JS Rao, K Ahn, SI Rapoport, H Blanchard PloS one 9 (6), e100858, 2014 | 30 | 2014 |
| Coordinated expression of phosphoinositide metabolic genes during development and aging of human dorsolateral prefrontal cortex SI Rapoport, CT Primiani, CT Chen, K Ahn, VH Ryan PLoS One 10 (7), e0132675, 2015 | 18 | 2015 |
| Meta-analysis of genetic modifiers reveals candidate dysregulated pathways in amyotrophic lateral sclerosis KS Yanagi, Z Wu, J Amaya, N Chapkis, AM Duffy, KH Hajdarovic, A Held, ... Neuroscience 396, A3-A20, 2019 | 17 | 2019 |
| Weak binding to the A2RE RNA rigidifies hnRNPA2 RRMs and reduces liquid–liquid phase separation and aggregation VH Ryan, S Watters, J Amaya, B Khatiwada, V Venditti, MT Naik, ... Nucleic Acids Research 48 (18), 10542-10554, 2020 | 14 | 2020 |
| sym-2 loss-of-function causes glutamatergic neurodegeneration after oxidative stress VH Ryan, AC Hart Micropublication Biology 2021, 2021 | 4 | 2021 |
| Messenger RNA transport on lysosomal vesicles maintains axonal mitochondrial homeostasis and prevents axonal degeneration R De Pace, S Ghosh, VH Ryan, M Sohn, M Jarnik, P Rezvan Sangsari, ... Nature Neuroscience, 1-16, 2024 | 1 | 2024 |
| Multi‐omic characterization of a novel FTD/ALS‐associated variant in ANXA11 A Snyder, V Ryan, A Qi, K Johnson, X Reed, MR Cookson, M Ward Alzheimer's & Dementia 19, e078408, 2023 | | 2023 |
