Jeremy Draghi
Jeremy Draghi
Biological Sciences, Virginia Tech
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Mutational robustness can facilitate adaptation
JA Draghi, TL Parsons, GP Wagner, JB Plotkin
Nature 463 (7279), 353-355, 2010
Phenotypic plasticity facilitates mutational variance, genetic variance, and evolvability along the major axis of environmental variation
JA Draghi, MC Whitlock
Evolution 66 (9), 2891-2902, 2012
Evolution of evolvability in a developmental model
J Draghi, GP Wagner
Evolution 62 (2), 301-315, 2008
The evolutionary dynamics of evolvability in a gene network model
J Draghi, GP Wagner
Journal of evolutionary biology 22 (3), 599-611, 2009
Local adaptation interacts with expansion load during range expansion: maladaptation reduces expansion load
KJ Gilbert, NP Sharp, AL Angert, GL Conte, JA Draghi, F Guillaume, ...
The American Naturalist 189 (4), 368-380, 2017
Mapping the fitness landscape of gene expression uncovers the cause of antagonism and sign epistasis between adaptive mutations
HH Chou, NF Delaney, JA Draghi, CJ Marx
PLoS genetics 10 (2), e1004149, 2014
Selection biases the prevalence and type of epistasis along adaptive trajectories
JA Draghi, JB Plotkin
Evolution 67 (11), 3120-3131, 2013
DNA secretion and gene-level selection in bacteria
JA Draghi, PE Turner
Microbiology 152 (9), 2683-2688, 2006
Correlational selection in the age of genomics
EI Svensson, SJ Arnold, R Bürger, K Csilléry, J Draghi, JM Henshaw, ...
Nature ecology & evolution 5 (5), 562-573, 2021
Evolution of evolvability
GP Wagner, J Draghi
Evolvability costs of niche expansion
LM Bono, JA Draghi, PE Turner
Trends in genetics 36 (1), 14-23, 2020
Experimentally guided models reveal replication principles that shape the mutation distribution of RNA viruses
MB Schulte, JA Draghi, JB Plotkin, R Andino
Elife 4, e03753, 2015
An amyloid core sequence in the major Candida albicans adhesin Als1p mediates cell-cell adhesion
V Ho, P Herman-Bausier, C Shaw, KA Conrad, MC Garcia-Sherman, ...
MBio 10 (5), 10.1128/mbio. 01766-19, 2019
Epistasis increases the rate of conditionally neutral substitution in an adapting population
JA Draghi, TL Parsons, JB Plotkin
Genetics 187 (4), 1139-1152, 2011
Existing host range mutations constrain further emergence of RNA viruses
L Zhao, M Seth-Pasricha, D Stemate, A Crespo-Bellido, J Gagnon, ...
Journal of Virology 93 (4), 10.1128/jvi. 01385-18, 2019
Robustness to noise in gene expression evolves despite epistatic constraints in a model of gene networks
J Draghi, M Whitlock
Evolution 69 (9), 2345-2358, 2015
High-throughput analysis of growth differences among phage strains
PE Turner, JA Draghi, R Wilpiszeski
Journal of microbiological methods 88 (1), 117-121, 2012
Phenotypic variability can promote the evolution of adaptive plasticity by reducing the stringency of natural selection
J Draghi
Journal of evolutionary biology 32 (11), 1274-1289, 2019
Developmental noise and ecological opportunity across space can release constraints on the evolution of plasticity
J Draghi
Evolution & Development 22 (1-2), 35-46, 2020
In evolution, the sum is less than its parts
S Kryazhimskiy, JA Draghi, JB Plotkin
science 332 (6034), 1160-1161, 2011
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