Gary Mirams
Gary Mirams
Centre for Mathematical Medicine & Biology, University of Nottingham
Verified email at nottingham.ac.uk - Homepage
TitleCited byYear
Chaste: an open source C++ library for computational physiology and biology
GR Mirams, CJ Arthurs, MO Bernabeu, R Bordas, J Cooper, A Corrias, ...
PLoS computational biology 9 (3), e1002970, 2013
2852013
Simulation of multiple ion channel block provides improved early prediction of compounds’ clinical torsadogenic risk
GR Mirams, Y Cui, A Sher, M Fink, J Cooper, BM Heath, NC McMahon, ...
Cardiovascular research 91 (1), 53, 2011
2322011
Chaste: a test-driven approach to software development for biological modelling
J Pitt-Francis, P Pathmanathan, MO Bernabeu, R Bordas, J Cooper, ...
Computer Physics Communications 180 (12), 2452-2471, 2009
2272009
An integrative computational model for intestinal tissue renewal
IMM Van Leeuwen, GR Mirams, A Walter, A Fletcher, P Murray, J Osborne, ...
Cell proliferation 42 (5), 617-636, 2009
1392009
Application of human stem cell-derived cardiomyocytes in safety pharmacology requires caution beyond hERG
MKB Jonsson, MA Vos, GR Mirams, G Duker, P Sartipy, TP de Boer, ...
Journal of Molecular and Cellular Cardiology 52 (5), 998-1008, 2012
1252012
A hybrid approach to multi-scale modelling of cancer
JM Osborne, A Walter, SK Kershaw, GR Mirams, AG Fletcher, ...
Philosophical Transactions of the Royal Society A: Mathematical, Physical …, 2010
1162010
Computational assessment of drug‐induced effects on the electrocardiogram: from ion channel to body surface potentials
N Zemzemi, MO Bernabeu, J Saiz, J Cooper, P Pathmanathan, ...
British Journal of Pharmacology 168 (3), 718-733, 2012
942012
A computational study of discrete mechanical tissue models
P Pathmanathan, J Cooper, A Fletcher, G Mirams, P Murray, J Osborne, ...
Physical biology 6, 036001, 2009
902009
Application of cardiac electrophysiology simulations to pro‐arrhythmic safety testing
GR Mirams, MR Davies, Y Cui, P Kohl, D Noble
British Journal of Pharmacology 167 (5), 932-945, 2012
862012
mRNA Expression Levels in Failing Human Hearts Predict Cellular Electrophysiological Remodeling: A Population-Based Simulation Study
J Walmsley, JF Rodriguez, GR Mirams, K Burrage, IR Efimov, ...
PLOS ONE 8 (2), e56359, 2013
742013
Prediction of Thorough QT study results using action potential simulations based on ion channel screens
GR Mirams, MR Davies, SJ Brough, MH Bridgland-Taylor, Y Cui, ...
Journal of pharmacological and toxicological methods 70 (3), 246-254, 2014
722014
Uncertainty and variability in models of the cardiac action potential: Can we build trustworthy models?
RH Johnstone, ETY Chang, R Bardenet, TP De Boer, DJ Gavaghan, ...
Journal of molecular and cellular cardiology 96, 49-62, 2016
702016
Uncertainty and variability in computational and mathematical models of cardiac physiology
GR Mirams, P Pathmanathan, RA Gray, P Challenor, RH Clayton
The Journal of physiology 594 (23), 6833-6847, 2016
672016
A theoretical investigation of the effect of proliferation and adhesion on monoclonal conversion in the colonic crypt
GR Mirams, AG Fletcher, PK Maini, HM Byrne
Journal of Theoretical Biology 312 (7), 143-156, 2012
632012
Variability in high-throughput ion-channel screening data and consequences for cardiac safety assessment
RC Elkins, MR Davies, SJ Brough, DJ Gavaghan, Y Cui, N Abi-Gerges, ...
Journal of pharmacological and toxicological methods 68 (1), 112-122, 2013
592013
A multiple timescale analysis of a mathematical model of the Wnt/β-catenin signalling pathway
GR Mirams, HM Byrne, JR King
Journal of mathematical biology 60 (1), 131-160, 2010
542010
High-throughput functional curation of cellular electrophysiology models
J Cooper, GR Mirams, SA Niederer
Progress in Biophysics and Molecular Biology 107 (1), 11-20, 2011
532011
Minimum Information about a Cardiac Electrophysiology Experiment (MICEE): standardised reporting for model reproducibility, interoperability, and data sharing
TA Quinn, S Granite, MA Allessie, C Antzelevitch, C Bollensdorff, G Bub, ...
Progress in biophysics and molecular biology 107 (1), 4-10, 2011
502011
Evaluation of an In Silico Cardiac Safety Assay: Using Ion Channel Screening Data to Predict QT Interval Changes in the Rabbit Ventricular Wedge
KA Beattie, C Luscombe, G Williams, J Munoz-Muriedas, DJ Gavaghan, ...
Journal of pharmacological and toxicological methods, 2013
492013
Modelling Spatially Regulated Beta-Catenin Dynamics and Invasion in Intestinal Crypts
PJ Murray, JW Kang, GR Mirams, SY Shin, HM Byrne, PK Maini, KH Cho
Biophysical journal 99 (3), 716-725, 2010
462010
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Articles 1–20