Obesity phenotype is related to NLRP3 inflammasome activity and immunological profile of visceral adipose tissue N Esser, L L’homme, A De Roover, L Kohnen, AJ Scheen, M Moutschen, ... Diabetologia 56 (11), 2487-2497, 2013 | 278 | 2013 |
Unsaturated fatty acids prevent activation of NLRP3 inflammasome in human monocytes/macrophages L L'homme, N Esser, L Riva, A Scheen, N Paquot, J Piette, ... Journal of lipid research 54 (11), 2998-3008, 2013 | 184 | 2013 |
Free fatty acids as modulators of the NLRP3 inflammasome in obesity/type 2 diabetes S Legrand-Poels, N Esser, L L’homme, A Scheen, N Paquot, J Piette Biochemical pharmacology 92 (1), 131-141, 2014 | 180 | 2014 |
Metabolic and Innate Immune Cues Merge into a Specific Inflammatory Response via the UPR DA Mogilenko, JT Haas, L L’homme, S Fleury, S Quemener, ... Cell 177 (5), 1201-1216. e19, 2019 | 126 | 2019 |
Saturated fatty acids induce NLRP3 activation in human macrophages through K+ efflux resulting from phospholipid saturation and Na, K-ATPase disruption MA Gianfrancesco, J Dehairs, L L'homme, G Herinckx, N Esser, O Jansen, ... Biochimica et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids …, 2019 | 75 | 2019 |
Inflammatory properties and adjuvant potential of synthetic glycolipids homologous to mycolate esters of the cell wall of Mycobacterium tuberculosis HG Tima, O Denis, P Lehebel, KS Baols, MO Mohammed, L L'Homme, ... Journal of Innate Immunity 9 (2), 162-180, 2017 | 37 | 2017 |
RIP3 antagonizes a TSC2-mediated pro-survival pathway in glioblastoma cell death G Fettweis, E Di Valentin, L L'homme, C Lassence, F Dequiedt, M Fillet, ... Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1864 (1), 113-124, 2017 | 23 | 2017 |
Saturated Fatty Acids Promote GDF15 Expression in Human Macrophages through the PERK/eIF2/CHOP Signaling Pathway L L’homme, BP Sermikli, B Staels, J Piette, S Legrand-Poels, ... Nutrients 12 (12), 3771, 2020 | 16 | 2020 |
Identification of piperazinylbenzenesulfonamides as new inhibitors of claudin-1 trafficking and hepatitis C virus entry L Riva, OR Song, J Prentoe, F Helle, L L'homme, CH Gattolliat, ... Journal of Virology 92 (10), 10.1128/jvi. 01982-17, 2018 | 15 | 2018 |
IFNγ-producing NK cells in adipose tissue are associated with hyperglycemia and insulin resistance in obese women DA Mogilenko, R Caiazzo, L L’homme, L Pineau, V Raverdy, J Noulette, ... International Journal of Obesity 45 (7), 1607-1617, 2021 | 11 | 2021 |
Deletion of the ORF9p acidic cluster impairs the nuclear egress of varicella-zoster virus capsids L Riva, M Thiry, M Lebrun, L L'homme, J Piette, C Sadzot-Delvaux Journal of virology 89 (4), 2436-2441, 2015 | 10 | 2015 |
Deletion of the nuclear receptor RORα in macrophages does not modify the development of obesity, insulin resistance and NASH L L’homme, BP Sermikli, O Molendi-Coste, S Fleury, S Quemener, ... Scientific reports 10 (1), 21095, 2020 | 6 | 2020 |
Liver-specific RORα deletion does not affect the metabolic susceptibility to western style diet feeding A Molinaro, R Caesar, L L'homme, A Koh, M Ståhlman, B Staels, ... Molecular metabolism 23, 82-87, 2019 | 4 | 2019 |
Novel XBP1s-independent function of IRE1 RNase in HIF-1α-mediated glycolysis upregulation in human macrophages upon stimulation with LPS or saturated fatty acid M Iovino, M Colonval, C Wilkin, L L’homme, C Lassence, M Campas, ... Frontiers in Immunology 14, 2023 | 3 | 2023 |
in vitro models of human mast cells: How to get more and better with induced pluripotent stem cells? L L'homme, D Dombrowicz The Journal of Allergy and Clinical Immunology, 2022 | 2 | 2022 |
IRE1 endoribonuclease plays a key role in activation of both HIF-1alpha and glucose metabolism in saturated fatty acid-treated human macrophages M Iovino, C Wilkin, M Colonval, L L'Homme, M Campas, M Schoumacher, ... Cell Symposium: Translational Immunometabolism, 2022 | | 2022 |
Key role of the IRE1-XBP1s pathway in metabolic reprogramming of human macrophages in response to saturated fatty acids and LPS M Iovino, M Colonval, L L'homme, P De Tullio, N Paquot, J Piette, ... EUROPEAN JOURNAL OF IMMUNOLOGY 51, 242-242, 2021 | | 2021 |
Astrotactin 1-derived peptide (AP): a new skin-penetrating peptide against inflammatory skin diseases L L'homme, D Dombrowicz Journal of Allergy and Clinical Immunology 141 (1), 86-88, 2018 | | 2018 |
The saturation of membrane phospholipids would be a trigger for K+ efflux and NLRP3 inflammasome activation in human monocytes/macrophages MA Gianfrancesco, J Dehairs, K Bloch, L L'homme, M Colonval, J Piette, ... Diabetologia 60, S290-S290, 2017 | | 2017 |
Investigation of the glycolytic switch induced by saturated fatty acid in human macrophages M Colonval, G Fettweis, L L'homme, J Piette, S Legrand Keystone-Integrating metabolism and immunity joint with the meeting on cell …, 2017 | | 2017 |