Andrew Horti

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James Robert BrasicAssistant Professor of Radiology and Radiological Science, Johns Hopkins UniversityVerified email at jhmi.edu
Jennifer M CoughlinAssociate Professor, Johns Hopkins University School of MedicineVerified email at jhmi.edu
Ayon NandiDivision of Nuclear Medicine and Molecular Imaging, Depart of Radiology, Johns Hopkins UniversityVerified email at jhmi.edu
Yuchuan WangMerck Research LabsVerified email at merck.com
Arman RahmimProfessor of Radiology, Physics and Biomedical Engineering, University of British ColumbiaVerified email at ubc.ca
Alena SavonenkoAssociate Professor, Pathology Department, Johns Hopkins University School of MedicineVerified email at jhmi.edu
Juan TroncosoProfessor of Pathology, Johns Hopkins University School of MedicineVerified email at jhmi.edu
Sridhar NimmagaddaProfessor of Radiology and Oncology, Johns Hopkins UniversityVerified email at jhmi.edu
gary wandProfessor of Medicine, The Johns Hopkins UniversityVerified email at jhmi.edu
Elliot SteinNIH/NIDA-IRPVerified email at mail.nih.gov
Youngjoo ByunProfessor, College of Pharmacy, Korea UniversityVerified email at korea.ac.kr
Sangeeta Ray BanerjeeAssociate Professor, Johns Hopkins UniversityVerified email at jhmi.edu
Christopher J. EndresFINRAVerified email at finra.org
Peter WillisNational Institute on Drug AbuseVerified email at indiana.edu
Alexander F. Hoffman, Ph.D.National Institutes of Health, National Institute on Drug Abuse Intramural Research ProgramVerified email at intra.nida.nih.gov
Richard L. WahlDirector of Mallinckrodt Institute of Radiology, Washington University School of Medicine, ProfessorVerified email at wustl.edu
dennis charneyicahn schoold of medicine at mount sinaiVerified email at mssm.edu
J Douglas BremnerEmory UniversityVerified email at emory.edu
Tatiana MelnikovaAssistant Professor JHMIVerified email at jhmi.edu
Marina PicciottoCharles B.G. Murphy Professor in Psychiatry, Yale UniversityVerified email at yale.edu

Andrew Horti

Johns Hopkins University

Verified email at jhmi.edu

radiochemistry medicinal chemistry positron emission tomography PET neuropharmacology


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⁶⁸Ga-Labeled Inhibitors of Prostate-Specific Membrane Antigen (PSMA) for Imaging Prostate Cancer SR Banerjee, M Pullambhatla, Y Byun, S Nimmagadda, G Green, JJ Fox, ... Journal of medicinal chemistry 53 (14), 5333-5341, 2010	306	2010
Quantification of cerebral cannabinoid receptors subtype 1 (CB1) in healthy subjects and schizophrenia by the novel PET radioligand [11C] OMAR DF Wong, H Kuwabara, AG Horti, V Raymont, J Brasic, M Guevara, W Ye, ... Neuroimage 52 (4), 1505-1513, 2010	211	2010
5-Iodo-A-85380, an α4β2 subtype-selective ligand for nicotinic acetylcholine receptors AG Mukhin, D Gündisch, AG Horti, AO Koren, G Tamagnan, AS Kimes, ... Molecular pharmacology 57 (3), 642-649, 2000	211	2000
PET imaging of microglia by targeting macrophage colony-stimulating factor 1 receptor (CSF1R) AG Horti, R Naik, CA Foss, I Minn, V Misheneva, Y Du, Y Wang, ... Proceedings of the National Academy of Sciences 116 (5), 1686-1691, 2019	162	2019
Synthesis, structure− activity relationship, and evaluation of SR141716 analogues: Development of central cannabinoid receptor ligands with lower lipophilicity R Katoch-Rouse, OA Pavlova, T Caulder, AF Hoffman, AG Mukhin, ... Journal of medicinal chemistry 46 (4), 642-645, 2003	162	2003
Greater nicotinic acetylcholine receptor density in smokers than in nonsmokers: a PET study with 2-18F-FA-85380 AG Mukhin, AS Kimes, SI Chefer, JA Matochik, CS Contoreggi, AG Horti, ... Journal of Nuclear Medicine 49 (10), 1628-1635, 2008	160	2008
2-, 5-, and 6-Halo-3-(2 (S)-azetidinylmethoxy) pyridines: synthesis, affinity for nicotinic acetylcholine receptors, and molecular modeling AO Koren, AG Horti, AG Mukhin, D Gündisch, AS Kimes, RF Dannals, ... Journal of medicinal chemistry 41 (19), 3690-3698, 1998	157	1998
2 [¹⁸F]F‐A85380: PET imaging of brain nicotinic acetylcholine receptors and whole body distribution in humans AS Kimes, AG Horti, ED London, SI Chefer, C Contoreggi, M Ernst, ... The FASEB journal 17 (10), 1331-1333, 2003	149	2003
High-potency ligands for DREADD imaging and activation in rodents and monkeys J Bonaventura, MAG Eldridge, F Hu, JL Gomez, M Sanchez-Soto, ... Nature communications 10 (1), 4627, 2019	145	2019
11C-JHU75528: a radiotracer for PET imaging of CB1 cannabinoid receptors AG Horti, H Fan, H Kuwabara, J Hilton, HT Ravert, DP Holt, M Alexander, ... Journal of Nuclear Medicine 47 (10), 1689-1696, 2006	128	2006
Synthesis and biodistribution of [11C] A-836339, a new potential radioligand for PET imaging of cannabinoid type 2 receptors (CB2) AG Horti, Y Gao, HT Ravert, P Finley, H Valentine, DF Wong, CJ Endres, ... Bioorganic & medicinal chemistry 18 (14), 5202-5207, 2010	122	2010
[125I] IPH, an epibatidine analog, binds with high affinity to neuronal nicotinic cholinergic receptors MI Dávila-García, JL Musachio, DC Perry, Y Xiao, A Horti, ED London, ... Journal of Pharmacology and Experimental Therapeutics 282 (1), 445-451, 1997	116	1997
Cannabinoid CB2 receptors in a mouse model of Aβ amyloidosis: immunohistochemical analysis and suitability as a PET biomarker of neuroinflammation AV Savonenko, T Melnikova, Y Wang, H Ravert, Y Gao, J Koppel, D Lee, ... PloS one 10 (6), e0129618, 2015	114	2015
2-[18F] Fluoro-A-85380, an in vivo tracer for the nicotinic acetylcholine receptors AG Horti, U Scheffel, AO Koren, HT Ravert, WB Mathews, JL Musachio, ... Nuclear medicine and biology 25 (7), 599-603, 1998	100	1998
Graphical analysis of 2‐[¹⁸F]FA binding to nicotinic acetylcholine receptors in rhesus monkey brain SI Chefer, ED London, AO Koren, OA Pavlova, V Kurian, AS Kimes, ... Synapse 48 (1), 25-34, 2003	92	2003
Whole-body biodistribution, radiation absorbed dose, and brain SPET imaging with [¹²³I]5-I-A-85380 in healthy human subjects M Fujita, JP Seibyl, BD Vaupel, G Tamagnan, M Early, SS Zoghbi, ... European journal of nuclear medicine and molecular imaging 29, 183-190, 2002	81	2002
Human Brain Imaging of α7 nAChR with [¹⁸F]ASEM: a New PET Radiotracer for Neuropsychiatry and Determination of Drug Occupancy DF Wong, H Kuwabara, M Pomper, DP Holt, JR Brasic, N George, ... Molecular imaging and biology 16, 730-738, 2014	78	2014
Imaging nicotinic acetylcholine receptors with fluorine-18-FPH, an epibatidine analog HN Wagner Jr, RF Dannals, VL Villemagne, A Horti, U Scheffel, HT Ravert, ... J Nucl Med 38, 1737-1741, 1997	78	1997
Synthesis of a radiotracer for studying nicotinic acetylcholine receptors: (+/−)‐exo‐2‐(2‐[¹⁸F]fluoro‐5‐pyridyl)‐7‐azabicyclo[2.2.1]heptane A Horti, HT Ravert, ED London, RF Dannals Journal of Labelled Compounds and Radiopharmaceuticals 38 (4), 355-365, 1996	77	1996
Synthesis of a radiotracer for studying nicotinic acetylcholine receptors: (+/−)‐exo‐2‐(2‐[¹⁸F]fluoro‐5‐pyridyl)‐7‐azabicyclo[2.2.1]heptane A Horti, HT Ravert, ED London, RF Dannals Journal of Labelled Compounds and Radiopharmaceuticals 38 (4), 355-365, 1996	77	1996

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