Jochen Weile
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Widespread macromolecular interaction perturbations in human genetic disorders
N Sahni, S Yi, M Taipale, JIF Bass, J Coulombe-Huntington, F Yang, ...
Cell 161 (3), 647-660, 2015
3732015
A reference map of the human binary protein interactome
K Luck, DK Kim, L Lambourne, K Spirohn, BE Begg, W Bian, R Brignall, ...
Nature 580 (7803), 402-408, 2020
204*2020
Pooled‐matrix protein interaction screens using Barcode Fusion Genetics
N Yachie, E Petsalaki, JC Mellor, J Weile, Y Jacob, M Verby, SB Ozturk, ...
Molecular systems biology 12 (4), 863, 2016
812016
A framework for exhaustively mapping functional missense variants
J Weile, S Sun, AG Cote, J Knapp, M Verby, JC Mellor, Y Wu, C Pons, ...
Molecular systems biology 13 (12), 957, 2017
742017
Integrative pathway dissection of molecular mechanisms of moxLDL-induced vascular smooth muscle phenotype transformation
GS Karagiannis, J Weile, GD Bader, J Minta
BMC cardiovascular disorders 13 (1), 1-19, 2013
562013
KeyPathwayMiner: detecting case-specific biological pathways using expression data
N Alcaraz, H Kücük, J Weile, A Wipat, J Baumbach
Internet Mathematics 7 (4), 299-313, 2011
532011
Multiplexed assays of variant effects contribute to a growing genotype–phenotype atlas
J Weile, FP Roth
Human genetics 137 (9), 665-678, 2018
442018
MaveDB: an open-source platform to distribute and interpret data from multiplexed assays of variant effect
D Esposito, J Weile, J Shendure, LM Starita, AT Papenfuss, FP Roth, ...
Genome biology 20 (1), 1-11, 2019
362019
An integrated dataset for in silico drug discovery
SJ Cockell, J Weile, P Lord, C Wipat, D Andriychenko, M Pocock, ...
Journal of integrative bioinformatics 7 (3), 15-27, 2010
362010
Mapping DNA damage‐dependent genetic interactions in yeast via party mating and barcode fusion genetics
JJ Díaz‐Mejía, A Celaj, JC Mellor, A Coté, A Balint, B Ho, P Bansal, ...
Molecular systems biology 14 (5), e7985, 2018
212018
CoryneRegNet 2: an integrative bioinformatics approach for reconstruction and comparison of transcriptional regulatory networks in prokaryotes
J Baumbach, K Brinkrolf, T Wittkop, A Tauch, S Rahmann
Journal of Integrative Bioinformatics 3 (2), 1-13, 2006
21*2006
Bayesian integration of networks without gold standards
J Weile, K James, J Hallinan, SJ Cockell, P Lord, A Wipat, D Wilkinson
Bioinformatics 28 (11), 1495-1500, 2012
162012
CoryneCenter–an online resource for the integrated analysis of corynebacterial genome and transcriptome data
H Neuweger, J Baumbach, S Albaum, T Bekel, M Dondrup, AT Hüser, ...
BMC systems biology 1 (1), 1-12, 2007
152007
A proactive genotype-to-patient-phenotype map for cystathionine beta-synthase
S Sun, J Weile, M Verby, Y Wu, Y Wang, AG Cote, I Fotiadou, ...
Genome medicine 12 (1), 1-18, 2020
122020
Assessing predictions of fitness effects of missense mutations in SUMO‐conjugating enzyme UBE2I
J Zhang, LN Kinch, Q Cong, J Weile, S Sun, AG Cote, FP Roth, NV Grishin
Human mutation 38 (9), 1051-1063, 2017
122017
Customizable views on semantically integrated networks for systems biology
J Weile, M Pocock, SJ Cockell, P Lord, JM Dewar, EM Holstein, ...
Bioinformatics 27 (9), 1299-1306, 2011
112011
Linking life sciences data using graph-based mapping
J Taubert, M Hindle, A Lysenko, J Weile, J Köhler, CJ Rawlings
International Workshop on Data Integration in the Life Sciences, 16-30, 2009
72009
A web application and service for imputing and visualizing missense variant effect maps
Y Wu, J Weile, AG Cote, S Sun, J Knapp, M Verby, FP Roth
Bioinformatics 35 (17), 3191-3193, 2019
62019
Systematic analysis of bypass suppression of essential genes
J van Leeuwen, C Pons, G Tan, JZ Wang, J Hou, J Weile, M Gebbia, ...
Molecular systems biology 16 (9), e9828, 2020
52020
Assessing predictions on fitness effects of missense variants in calmodulin
J Zhang, LN Kinch, Q Cong, P Katsonis, O Lichtarge, C Savojardo, ...
Human mutation 40 (9), 1463-1473, 2019
42019
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