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Lindsey Lee
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Sleeping Beauty Insertional Mutagenesis in Mice Identifies Drivers of Steatosis-Associated Hepatic Tumors
BR Tschida, NA Temiz, TP Kuka, LA Lee, JD Riordan, CA Tierrablanca, ...
Cancer research 77 (23), 6576-6588, 2017
392017
The ancient sarcomeric myosins found in specialized muscles
LA Lee, A Karabina, LJ Broadwell, LA Leinwand
Skeletal muscle 9, 1-15, 2019
372019
Norrin-induced Frizzled4 endocytosis and endo-lysosomal trafficking control retinal angiogenesis and barrier function
C Zhang, MB Lai, L Khandan, LA Lee, Z Chen, HJ Junge
Nature communications 8 (1), 16050, 2017
302017
Drug specificity and affinity are encoded in the probability of cryptic pocket opening in myosin motor domains
A Meller, JM Lotthammer, LG Smith, B Novak, LA Lee, CC Kuhn, ...
Elife 12, e83602, 2023
172023
Expression of normally repressed myosin heavy chain 7b in the mammalian heart induces dilated cardiomyopathy
AK Peter, AC Rossi, M Buvoli, CD Ozeroff, C Crocini, AR Perry, AE Buvoli, ...
Journal of the American Heart Association 8 (15), e013318, 2019
172019
Functional divergence of the sarcomeric myosin, MYH7b, supports species-specific biological roles
LA Lee, SK Barrick, A Meller, J Walklate, JM Lotthammer, JW Tay, ...
Journal of Biological Chemistry 299 (1), 2023
122023
Ras oncogene-independent activation of RALB signaling is a targetable mechanism of escape from NRAS (V12) oncogene addiction in acute myeloid leukemia
EJ Pomeroy, LA Lee, RDW Lee, DK Schirm, NA Temiz, J Ma, TA Gruber, ...
Oncogene 36 (23), 3263-3273, 2017
122017
RALB provides critical survival signals downstream of Ras in acute myeloid leukemia
CE Eckfeldt, EJ Pomeroy, RDW Lee, KS Hazen, LA Lee, BS Moriarity, ...
Oncotarget 7 (40), 65147, 2016
72016
Nonproductive splicing prevents expression of MYH7b protein in the mammalian heart
LA Lee, LJ Broadwell, M Buvoli, LA Leinwand
Journal of the American Heart Association 10 (14), e020965, 2021
62021
Distinct effects of two hearing loss–associated mutations in the sarcomeric myosin MYH7b
LA Lee, SK Barrick, AE Buvoli, J Walklate, WT Stump, M Geeves, ...
Journal of Biological Chemistry 299 (5), 2023
12023
Drug specificity and affinity are encoded in the probability of cryptic pocket opening in myosin motor domains
A Meller, JM Lotthammer, LG Smith, B Novak, LA Lee, CC Kuhn, ...
bioRxiv, 2022.09. 05.506254, 2022
12022
CHRONIC TREATMENT WITH THE NOVEL SARCOMERE MODULATOR EDG-7500 IMPROVES LEFT VENTRICULAR DISTENSIBILITY AND CARDIAC OUTPUT RECRUITMENT UNDER STRESS IN A MINIPIG GENETIC MODEL OF …
M Evanchik, C Emter, CL del Rio, E Dinatale, M Henze, S Roof, S St Clair, ...
Journal of the American College of Cardiology 83 (13_Supplement), 365-365, 2024
2024
Functional Divergence of the Atypical Sarcomeric Myosin Myh7b Supports Specialized Biological Roles across Species
LA Lee
University of Colorado at Boulder, 2022
2022
Functional Differences in MYH7b That Contribute to Distinct Biological Roles across Species and in Health and Disease
LA Lee, A Karabina, LA Leinwand
Biophysical Journal 118 (3), 433a, 2020
2020
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