Suivre
George Sharbeen
George Sharbeen
Post-Doctoral Researcher, UNSW Australia
Adresse e-mail validée de unsw.edu.au
Titre
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Année
Role of pancreatic stellate cells in chemoresistance in pancreatic cancer
JA McCarroll, S Naim, G Sharbeen, J Lee, M Kavallaris, D Goldstein, ...
Frontiers in physiology 5, 141, 2014
1872014
Effective delivery of siRNA into cancer cells and tumors using well-defined biodegradable cationic star polymers
C Boyer, J Teo, P Phillips, RB Erlich, S Sagnella, G Sharbeen, T Dwarte, ...
Molecular pharmaceutics 10 (6), 2435-2444, 2013
1172013
A rationally optimized nanoparticle system for the delivery of RNA interference therapeutics into pancreatic tumors in vivo
J Teo, JA McCarroll, C Boyer, J Youkhana, SM Sagnella, HTT Duong, ...
Biomacromolecules 17 (7), 2337-2351, 2016
822016
βIII-tubulin: a novel mediator of chemoresistance and metastases in pancreatic cancer
JA McCarroll, G Sharbeen, J Liu, J Youkhana, D Goldstein, N McCarthy, ...
Oncotarget 6 (4), 2235, 2015
762015
A novel role of dipeptidyl peptidase 9 in epidermal growth factor signaling
TW Yao, WS Kim, DMT Yu, G Sharbeen, GW McCaughan, KY Choi, P Xia, ...
Molecular Cancer Research 9 (7), 948-959, 2011
702011
Cancer-associated fibroblasts in pancreatic ductal adenocarcinoma determine response to SLC7A11 inhibition
G Sharbeen, JA McCarroll, A Akerman, C Kopecky, J Youkhana, ...
Cancer research 81 (13), 3461-3479, 2021
672021
Ectopic restriction of DNA repair reveals that UNG2 excises AID-induced uracils predominantly or exclusively during G1 phase
G Sharbeen, CWY Yee, AL Smith, CJ Jolly
Journal of Experimental Medicine 209 (5), 965-974, 2012
642012
Targeting the undruggable in pancreatic cancer using nano-based gene silencing drugs
J Kokkinos, RMC Ignacio, G Sharbeen, C Boyer, E Gonzales-Aloy, ...
Biomaterials 240, 119742, 2020
572020
Ex vivo culture of intact human patient derived pancreatic tumour tissue
J Kokkinos, G Sharbeen, KS Haghighi, RMC Ignacio, C Kopecky, ...
Scientific reports 11 (1), 1944, 2021
392021
Exploiting base excision repair to improve therapeutic approaches for pancreatic cancer
G Sharbeen, J McCarroll, D Goldstein, PA Phillips
Frontiers in nutrition 2, 10, 2015
272015
Can the shape of nanoparticles enable the targeting to cancer cells over healthy cells?
VT Cong, W Wang, RD Tilley, G Sharbeen, PA Phillips, K Gaus, ...
Advanced Functional Materials 31 (32), 2007880, 2021
242021
Identification of novel medulloblastoma cell-targeting peptides for use in selective chemotherapy drug delivery
KC Tjandra, N McCarthy, L Yang, AJ Laos, G Sharbeen, PA Phillips, ...
Journal of medicinal chemistry 63 (5), 2181-2193, 2019
232019
Aerosol delivery of star polymer-siRNA nanoparticles as a therapeutic strategy to inhibit lung tumor growth
Z Ma, SW Wong, H Forgham, L Esser, M Lai, MN Leiske, K Kempe, ...
Biomaterials 285, 121539, 2022
192022
Delineating the role of βIV-tubulins in pancreatic cancer: βIVb-tubulin inhibition sensitizes pancreatic cancer cells to vinca alkaloids
G Sharbeen, J McCarroll, J Liu, J Youkhana, LF Limbri, AV Biankin, ...
Neoplasia 18 (12), 753-764, 2016
192016
Proximity to AGCT sequences dictates MMR-independent versus MMR-dependent mechanisms for AID-induced mutation via UNG2
ES Thientosapol, G Sharbeen, KKE Lau, D Bosnjak, T Durack, ...
Nucleic acids research 45 (6), 3146-3157, 2017
172017
MutY-Homolog (MYH) inhibition reduces pancreatic cancer cell growth and increases chemosensitivity
G Sharbeen, J Youkhana, A Mawson, J McCarroll, A Nunez, A Biankin, ...
Oncotarget 8 (6), 9216, 2017
162017
Biochemical Characterization of the Multidrug Regulator QacR Distinguishes Residues That Are Crucial to Multidrug Binding and Induction of qacA Transcription
KM Peters, G Sharbeen, T Theis, RA Skurray, MH Brown
Biochemistry 48 (41), 9794-9800, 2009
142009
A first-in-class pan-lysyl oxidase inhibitor impairs stromal remodeling and enhances gemcitabine response and survival in pancreatic cancer
JL Chitty, M Yam, L Perryman, AL Parker, JN Skhinas, YFI Setargew, ...
Nature Cancer 4 (9), 1326-1344, 2023
112023
Australian Pancreatic Cancer Genome Initiative A., McCarroll JA, Phillips PA Targeting the undruggable in pancreatic cancer using nano-based gene silencing drugs
J Kokkinos, RMC Ignacio, G Sharbeen, C Boyer, E Gonzales-Aloy, ...
Biomaterials 240 (119742), 10.1016, 2020
112020
Interfacial curvature in confined coculture directs stromal cell activity with spatial corralling of pancreatic cancer cells
S Nemec, J Lam, J Zhong, C Heu, P Timpson, Q Li, J Youkhana, ...
Advanced Biology 5 (6), 2000525, 2021
102021
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