| Distinct roles for JNK1 and JNK2 in regulating JNK activity and c-Jun-dependent cell proliferation K Sabapathy, K Hochedlinger, SY Nam, A Bauer, M Karin, EF Wagner Molecular cell 15 (5), 713-725, 2004 | 476 | 2004 |
| Defective neural tube morphogenesis and altered apoptosis in the absence of both JNK1 and JNK2 K Sabapathy, W Jochum, K Hochedlinger, L Chang, M Karin, EF Wagner Mechanisms of development 89 (1-2), 115-124, 1999 | 460 | 1999 |
| Therapeutic targeting of p53: all mutants are equal, but some mutants are more equal than others K Sabapathy, DP Lane Nature reviews Clinical oncology 15 (1), 13-30, 2018 | 414 | 2018 |
| JNK2 is required for efficient T-cell activation and apoptosis but not for normal lymphocyte development K Sabapathy, Y Hu, T Kallunki, M Schreiber, JP David, W Jochum, ... Current biology 9 (3), 116-125, 1999 | 398 | 1999 |
| JNK1 modulates osteoclastogenesis through both c-Jun phosphorylation-dependent and-independent mechanisms JP David, K Sabapathy, O Hoffmann, MH Idarraga, EF Wagner Journal of cell science 115 (22), 4317-4325, 2002 | 391 | 2002 |
| C-Jun Nh2-Terminal Kinase (Jnk)1 and Jnk2 Have Similar and Stage-Dependent Roles in Regulating T Cell Apoptosis and Proliferation K Sabapathy, T Kallunki, JP David, I Graef, M Karin, EF Wagner The Journal of experimental medicine 193 (3), 317-328, 2001 | 280 | 2001 |
| c-Jun promotes cellular survival by suppression of PTEN K Hettinger, F Vikhanskaya, MK Poh, MK Lee, I De Belle, JT Zhang, ... Cell Death & Differentiation 14 (2), 218-229, 2007 | 210 | 2007 |
| Functional crosstalk between type I and II interferon through the regulated expression of STAT1 DJ Gough, NL Messina, L Hii, JA Gould, K Sabapathy, APS Robertson, ... PLoS biology 8 (4), e1000361, 2010 | 195 | 2010 |
| An apoptotic signaling pathway in the interferon antiviral response mediated by RNase L and c-Jun NH2-terminal kinase G Li, Y Xiang, K Sabapathy, RH Silverman Journal of Biological Chemistry 279 (2), 1123-1131, 2004 | 190 | 2004 |
| Regulation of ES cell differentiation by functional and conformational modulation of p53 K Sabapathy, M Klemm, R Jaenisch, EF Wagner The EMBO journal, 1997 | 189 | 1997 |
| Role of the JNK pathway in human diseases K Sabapathy Progress in molecular biology and translational science 106, 145-169, 2012 | 181 | 2012 |
| Cancer-derived p53 mutants suppress p53-target gene expression—potential mechanism for gain of function of mutant p53 F Vikhanskaya, MK Lee, M Mazzoletti, M Broggini, K Sabapathy Nucleic acids research 35 (6), 2093-2104, 2007 | 176 | 2007 |
| Trp53-dependent DNA-repair is affected by the codon 72 polymorphism M Siddique, K Sabapathy Oncogene 25 (25), 3489-3500, 2006 | 169 | 2006 |
| Differential effects of JNK1 and JNK2 on signal specific induction of apoptosis K Hochedlinger, EF Wagner, K Sabapathy Oncogene 21 (15), 2441-2445, 2002 | 133 | 2002 |
| Genome-scale mutational signatures of aflatoxin in cells, mice, and human tumors MN Huang, W Yu, WW Teoh, M Ardin, A Jusakul, AWT Ng, A Boot, ... Genome research 27 (9), 1475-1486, 2017 | 111 | 2017 |
| JNK2: a negative regulator of cellular proliferation K Sabapathy, EF Wagner Cell Cycle 3 (12), 1520-1523, 2004 | 111 | 2004 |
| Jun N-terminal kinase 2 modulates thymocyte apoptosis and T cell activation through c-Jun and nuclear factor of activated T cell (NF-AT) A Behrens, K Sabapathy, I Graef, M Cleary, GR Crabtree, EF Wagner Proceedings of the National Academy of Sciences 98 (4), 1769-1774, 2001 | 110 | 2001 |
| Understanding p53 functions through p53 antibodies K Sabapathy, DP Lane Journal of molecular cell biology 11 (4), 317-329, 2019 | 103 | 2019 |
| c-Jun regulates the stability and activity of the p53 homologue, p73 WH Toh, MM Siddique, L Boominathan, KW Lin, K Sabapathy Journal of Biological Chemistry 279 (43), 44713-44722, 2004 | 99 | 2004 |
| Evidence for selective expression of the p53 codon 72 polymorphs: implications in cancer development MM Siddique, C Balram, L Fiszer-Maliszewska, A Aggarwal, A Tan, P Tan, ... Cancer Epidemiology Biomarkers & Prevention 14 (9), 2245-2252, 2005 | 96 | 2005 |
David M. VirshupDuke-NUS Medical School SingaporeAdresse e-mail validée de duke-nus.edu.sg
