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Paul RHJ Timmers
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Genome-wide association analyses of risk tolerance and risky behaviors in over 1 million individuals identify hundreds of loci and shared genetic influences
RK Linnér, P Biroli, E Kong, SFW Meddens, R Wedow, MA Fontana, ...
Nature genetics 51 (2), 245, 2019
5852019
The power of genetic diversity in genome-wide association studies of lipids
SE Graham, SL Clarke, KHH Wu, S Kanoni, GJM Zajac, S Ramdas, ...
Nature 600 (7890), 675-679, 2021
3792021
New genetic signals for lung function highlight pathways and chronic obstructive pulmonary disease associations across multiple ancestries
N Shrine, AL Guyatt, AM Erzurumluoglu, VE Jackson, BD Hobbs, ...
Nature genetics 51 (3), 481-493, 2019
3782019
The trans-ancestral genomic architecture of glycemic traits
J Chen, CN Spracklen, G Marenne, A Varshney, LJ Corbin, J Luan, ...
Nature genetics 53 (6), 840-860, 2021
3632021
Genetic landscape of chronic obstructive pulmonary disease identifies heterogeneous cell-type and phenotype associations
P Sakornsakolpat, D Prokopenko, M Lamontagne, NF Reeve, AL Guyatt, ...
Nature genetics 51 (3), 494-505, 2019
2862019
A saturated map of common genetic variants associated with human height
L Yengo, S Vedantam, E Marouli, J Sidorenko, E Bartell, S Sakaue, ...
Nature 610 (7933), 704-712, 2022
2722022
Whole-genome sequencing reveals host factors underlying critical COVID-19
A Kousathanas, E Pairo-Castineira, K Rawlik, A Stuckey, CA Odhams, ...
Nature 607 (7917), 97-103, 2022
2142022
Genetic insights into biological mechanisms governing human ovarian ageing
KS Ruth, FR Day, J Hussain, A Martínez-Marchal, CE Aiken, A Azad, ...
Nature 596 (7872), 393-397, 2021
2082021
Genomics of 1 million parent lifespans implicates novel pathways and common diseases and distinguishes survival chances
PRHJ Timmers, N Mounier, K Lall, K Fischer, Z Ning, X Feng, ...
eLife 8, e39856, 2019
2032019
Genome-wide meta-analysis associates HLA-DQA1/DRB1 and LPA and lifestyle factors with human longevity
PK Joshi, N Pirastu, KA Kentistou, K Fischer, E Hofer, KE Schraut, ...
Nature communications 8 (1), 910, 2017
1562017
Multivariate genomic scan implicates novel loci and haem metabolism in human ageing
PRHJ Timmers, JF Wilson, PK Joshi, J Deelen
Nature communications 11 (1), 3570, 2020
972020
A first update on mapping the human genetic architecture of COVID-19
Writing group lead Andrews Shea J. 6 Kanai Masahiro 3 Cordioli Mattia 7, ...
Nature 608 (7921), E1-E10, 2022
882022
Chronic obstructive pulmonary disease and related phenotypes: polygenic risk scores in population-based and case-control cohorts
M Moll, P Sakornsakolpat, N Shrine, BD Hobbs, DL DeMeo, C John, ...
The Lancet Respiratory Medicine 8 (7), 696-708, 2020
852020
Genomic analysis of male puberty timing highlights shared genetic basis with hair colour and lifespan
B Hollis, FR Day, AS Busch, DJ Thompson, ALG Soares, PRHJ Timmers, ...
Nature communications 11 (1), 1536, 2020
502020
Genome-Wide Association Study of NAFLD Using Electronic Health Records
CJ Fairfield, TM Drake, R Pius, AD Bretherick, A Campbell, DW Clark, ...
Hepatology Communications, 2021
382021
Low-frequency variation in TP53 has large effects on head circumference and intracranial volume
S Haworth, CY Shapland, C Hayward, BP Prins, JF Felix, ...
Nature communications 10 (1), 357, 2019
342019
An atlas of genetic scores to predict multi-omic traits
Y Xu, SC Ritchie, Y Liang, PRHJ Timmers, M Pietzner, L Lannelongue, ...
Nature 616 (7955), 123-131, 2023
282023
Implicating genes, pleiotropy, and sexual dimorphism at blood lipid loci through multi-ancestry meta-analysis
S Kanoni, SE Graham, Y Wang, I Surakka, S Ramdas, X Zhu, SL Clarke, ...
Genome biology 23 (1), 268, 2022
272022
SARS-CoV-2 susceptibility and COVID-19 disease severity are associated with genetic variants affecting gene expression in a variety of tissues
M D’Antonio, JP Nguyen, TD Arthur, H Matsui, BM Neale, M Daly, ...
Cell reports 37 (7), 2021
252021
A multi-layer functional genomic analysis to understand noncoding genetic variation in lipids
S Ramdas, J Judd, SE Graham, S Kanoni, Y Wang, I Surakka, B Wenz, ...
The American Journal of Human Genetics 109 (8), 1366-1387, 2022
212022
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